Search Results - "Lewalle, J M"

Down-regulation of vascular endothelial growth factor by tissue inhibitor of metalloproteinase-2 : Effect on in vivo mammary tumor growth and angiogenesis by HAJITOU, Amin, SOUNNI, Nor-Eddine, FRANKENNE, Francis, MARON, Anne, YEH, Patrice, PERRICAUDET, Michel, YAWEN CHANG, SORIA, Claudine, CALBERG-BACQ, Claire-Michelle, FOIDART, Jean-Michel, NOËL, Agnès, DEVY, Laetitia, GRIGNET-DEBRUS, Christine, LEWALLE, Jean-Marc, HONG LI, DEROANNE, Christophe F, HE LU, COLIGE, Alain, NUSGENS, Betty V

“…The tissue inhibitor of metalloproteinases-2 (TIMP-2) has at least two independent functions, i.e., regulation of matrix metalloproteinases and growth…”
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Induction of Endothelial Cell Apoptosis by Solid Tumor Cells by Kebers, Florence, Lewalle, Jean-Marc, Desreux, Joëlle, Munaut, Carine, Devy, Laetitia, Foidart, Jean-Michel, Noël, Agnès

“…The mechanisms by which tumor cells extravasate to form metastasis remain controversial. Previous studies performedin vivoandin vitrodemonstrate that the…”
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Induction of SPARC by VEGF in Human Vascular Endothelial Cells by Kato, Yasumasa, Lewalle, Jean-Marc, Baba, Yuh, Tsukuda, Mamoru, Sakai, Naoki, Baba, Masaya, Kobayashi, Kazuki, Koshika, Shinri, Nagashima, Yoji, Frankenne, Francis, Noël, Agnés, Foidart, Jean-Michel, Hata, Ryu-Ichiro

“…SPARC/osteonectin/BM-40 is a matricellular protein that is thought to be involved in angiogenesis and endothelial barrier function. Previously, we have…”
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Plasma membrane-dependent activation of gelatinase A in human vascular endothelial cells by Lewalle, J M, Munaut, C, Pichot, B, Cataldo, D, Baramova, E, Foidart, J M

“…The initiation of the angiogenic process requires a locally confined and time-limited proteolysis of the basement membrane (BM) components at the site of new…”
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Alteration of interendothelial adherens junctions following tumor cell-endothelial cell interaction in vitro by Lewalle, J M, Bajou, K, Desreux, J, Mareel, M, Dejana, E, Noël, A, Foidart, J M

“…The integrity of the vascular endothelium is mainly dependent upon the organization of interendothelial adherens junctions (AJ). These junctions are formed by…”
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Thrombospondin modulates human breast adenocarcinoma cell adhesion to human vascular endothelial cells by INCARDONA, F, LEWALLE, J. M, MORANDI, V, LAMBERT, S, LEGRAND, Y, FOIDART, J. M, LEGRAND, C

“…Thrombospondin (TSP), a M(r) 450,000 cytoadhesive glycoprotein, has been shown to potentiate tumor cell metastasis in mice by a mechanism that involves the…”
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Endothelial cell intracellular Ca2+ concentration is increased upon breast tumor cell contact and mediates tumor cell transendothelial migration by Lewalle, J M, Cataldo, D, Bajou, K, Lambert, C A, Foidart, J M

“…Tumor cell extravasation is a determinant step in the process of hematogenous metastasis. The signal transduction pathways involved in the interactions between…”
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Emerging roles for proteinases in cancer by Noël, A, Gilles, C, Bajou, K, Devy, L, Kebers, F, Lewalle, J M, Maquoi, E, Munaut, C, Remacle, A, Foidart, J M

“…Metalloproteinases and serine proteinases have been associated with tumor invasion and formation of metastasis which represent the major obstacles to cancer…”
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Inhibition of stromal matrix metalloproteases: Effects on breast‐tumor promotion by fibroblasts by Noël, Agnès, Hajitou, Amin, L'Hoir, Cécile, Maquoi, Erik, Baramova, Eugénia, Lewalle, Jean‐Marc, Remacle, Albert, Kebers, Florence, Brown, Peter, Calberg‐Bacq, Claire‐Michelle, Foidart, Jean‐Michel

“…Co‐injection of fibroblasts with human epithelial breast‐tumor MCF7 cells in the presence of Matrigel enhances tumor growth in nude mice. While most of the…”
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Rat chromosome 5 (q22-23) contains elements that control cell morphology and interactions with the extracellular matrix: a study of normal fibroblast x malignant hepatoma cell hybrids by Lewalle, J M, Szpirer, C, Szpirer, J, Munaut, C, Foidart, J M

“…Cell interactions with the extracellular matrix are consistently modified in neoplasia. Malignant transformation has been correlated with modifications in the…”
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Malignant cell attachment to endothelium of ex vivo perfused human umbilical vein. Modulation by platelets, plasma and fibronectin by Lewalle, J M, Castronovo, V, Goffinet, G, Foidart, J M

“…The success of blood-born metastatic spread depends upon a key event: the tumor cell arrest and attachment to the host organ vasculature. In the present study,…”
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Human breast adenocarcinoma cell lines promote angiogenesis by providing cells with uPA‐PAI‐1 and by enhancing their expression by Bajou, Khalid, Lewalle, Jean‐Marc, Martinez, Christian Rodriguez, Soria, Claudine, Lu, He, Noël, Agnès, Foidart, Jean‐Michel

“…During angiogenesis, endothelial cells use uPA and PAI‐1 to migrate and degrade the basement membrane surrounding capillary blood vessels. Invasive tumor cells…”
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Coordinate enhancement of gelatinase A mRNA and activity levels in human fibroblasts in response to breast-adenocarcinoma cells by Noël, A C, Polette, M, Lewalle, J M, Munaut, C, Emonard, H P, Birembaut, P, Foidart, J M

“…Gelatinases/type-IV collagenases are metalloproteinases involved in some carcinoma invasion and metastatic processes. The exact cellular source of the 72-kDa…”
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Experimental Cell Research by Lewalle, J. M, Bajou, Khalid, Desreux, Joëlle, Mareel, M, Dejana, E, Noël, Agnès, Foidart, Jean-Michel

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