Search Results - "Lewén, Anders"

Emergency neurosurgery for traumatic brain injury by general surgeons at local hospitals in Sweden: a viable option when time is brain by Leal-Méndez, Francisco, Holmberg, Lina, Enblad, Per, Lewén, Anders, Linder, Fredrik, Wettervik, Teodor Svedung

“…Abstract Background Timing of surgical evacuation of mass lesions in traumatic brain injury (TBI) is crucial. However, due to geographical variations,…”
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Fine tuning of neurointensive care in aneurysmal subarachnoid hemorrhage: From one-size-fits-all towards individualized care by Svedung Wettervik, Teodor, Lewén, Anders, Enblad, Per

“…Aneurysmal subarachnoid hemorrhage (aSAH) is a severe type of acute brain injury with high mortality and burden of neurological sequelae. General management…”
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Cerebral Microdialysis Monitoring of Energy Metabolism: Relation to Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage by Svedung Wettervik, Teodor, Engquist, Henrik, Hånell, Anders, Howells, Timothy, Rostami, Elham, Ronne-Engström, Elisabeth, Lewén, Anders, Enblad, Per

“…In this study, we investigated the roles of cerebral blood flow (CBF) and cerebral oxygen delivery (CDO2) in relation to cerebral energy metabolism after…”
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Overexpression of Copper/Zinc Superoxide Dismutase in Transgenic Rats Protects Vulnerable Neurons against Ischemic Damage by Blocking the Mitochondrial Pathway of Caspase Activation by Sugawara, Taku, Noshita, Nobuo, Lewen, Anders, Gasche, Yvan, Ferrand-Drake, Michel, Fujimura, Miki, Morita-Fujimura, Yuiko, Chan, Pak H

“…Mitochondria are known to be involved in the early stage of apoptosis by releasing cytochrome c, caspase-9, and the second mitochondria-derived activator of…”
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Evaluation and external validation of machine learning models predicting full spectrum GOSE outcome following traumatic brain injury by Bark, David, Boman, Magnus, Depreitere, Bart, Wright, David W., Lewén, Anders, Enblad, Per, Hånell, Anders, Rostami, Elham

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The Correlation between Cerebral Blood Flow Measured by Bedside Xenon-CT and Brain Chemistry Monitored by Microdialysis in the Acute Phase following Subarachnoid Hemorrhage by Rostami, Elham, Engquist, Henrik, Howells, Timothy, Ronne-Engström, Elisabeth, Nilsson, Pelle, Hillered, Lars Tomas, Lewén, Anders, Enblad, Per

“…Cerebral microdialysis (MD) may be used in patients suffering from subarachnoid hemorrhage (SAH) to detect focal cerebral ischemia. The cerebral MD catheter is…”
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Neurointensive care of traumatic brain injury in the elderly—age-specific secondary insult levels and optimal physiological levels to target need to be defined by Lenell, Samuel, Lewén, Anders, Howells, Timothy, Enblad, Per

“…Background Elderly patients with traumatic brain injury increase. Current targets and secondary insult definitions during neurointensive care (NIC) are mostly…”
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Pre-injury chronic alcohol abuse predicts intracranial hemorrhagic progression, unfavorable clinical outcome, and mortality in severe traumatic brain injury by Svedung Wettervik, Teodor, Enblad, Per, Lewén, Anders

“…We aimed to determine the incidence of pre-injury alcohol abuse in TBI at our neurointensive care unit (NICU), the relation to intracranial hemorrhage…”
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Cerebral Pressure Autoregulation in Brain Injury and Disorders–A Review on Monitoring, Management, and Future Directions by Svedung Wettervik, Teodor, Fahlström, Markus, Enblad, Per, Lewén, Anders

“…The role of cerebral pressure autoregulation (CPA) in brain injury and disorders has gained increased interest. The CPA is often disturbed as a consequence of…”
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Clinical outcome and prognostic factors in elderly traumatic brain injury patients receiving neurointensive care by Lenell, Samuel, Nyholm, Lena, Lewén, Anders, Enblad, Per

“…Background The probability of favorable outcome after traumatic brain injury (TBI) decreases with age. Elderly, ≥ 60 years, are an increasing part of our…”
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Temporal Dynamics of ICP, CPP, PRx, and CPPopt in High-Grade Aneurysmal Subarachnoid Hemorrhage and the Relation to Clinical Outcome by Svedung Wettervik, Teodor, Howells, Timothy, Lewén, Anders, Ronne-Engström, Elisabeth, Enblad, Per

“…Background High intracranial pressure (ICP) and low cerebral perfusion pressure (CPP) may induce secondary brain injury following aneurysmal subarachnoid…”
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Cerebral pressure autoregulation and optimal cerebral perfusion pressure during neurocritical care of children with traumatic brain injury by Velle, Fartein, Lewén, Anders, Howells, Timothy, Hånell, Anders, Nilsson, Pelle, Enblad, Per

“…The management of cerebral perfusion pressure (CPP) is a challenge in children with traumatic brain injury (TBI) because the normal blood pressure is age…”
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Arterial lactate in traumatic brain injury – Relation to intracranial pressure dynamics, cerebral energy metabolism and clinical outcome by Svedung Wettervik, Teodor, Engquist, Henrik, Howells, Timothy, Rostami, Elham, Hillered, Lars, Enblad, Per, Lewén, Anders

“…High arterial lactate is associated with disturbed systemic physiology. Lactate can also be used as alternative cerebral fuel and it is involved in regulating…”
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ICP, CPP, and PRx in traumatic brain injury and aneurysmal subarachnoid hemorrhage: association of insult intensity and duration with clinical outcome by Svedung Wettervik, Teodor, Hånell, Anders, Howells, Timothy, Ronne Engström, Elisabeth, Lewén, Anders, Enblad, Per

“…The primary aim of this study was to determine the combined effect of insult intensity and duration of intracranial pressure (ICP), cerebral perfusion pressure…”
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The effects of cerebral pressure autoregulation status and CPP levels on cerebral metabolism in pediatric traumatic brain injury by Velle, Fartein, Lewén, Anders, Howells, Tim, Hånell, Anders, Nilsson, Pelle, Enblad, Per

“…Background Cerebral perfusion pressure (CPP) management in the developing child with traumatic brain injury (TBI) is challenging. The pressure reactivity index…”
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Blood Pressure Variability and Optimal Cerebral Perfusion Pressure—New Therapeutic Targets in Traumatic Brain Injury by Svedung Wettervik, Teodor, Howells, Timothy, Lewén, Anders, Enblad, Per

“…Abstract BACKGROUND Optimal cerebral perfusion pressure (CPPopt) is an autoregulatory-oriented target in the neurointensive care (NIC) of patients with…”
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Temporal effects of barbiturate coma on intracranial pressure and compensatory reserve in children with traumatic brain injury by Velle, Fartein, Lewén, Anders, Howells, Timothy, Nilsson, Pelle, Enblad, Per

“…Background The aim was to study the effects of barbiturate coma treatment (BCT) on intracranial pressure (ICP) and intracranial compensatory reserve (RAP…”
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Should Patients with Traumatic Brain Injury with Significant Contusions be Treated with Different Neurointensive Care Targets? by Svedung Wettervik, Teodor, Hånell, Anders, Lewén, Anders, Enblad, Per

“…Background Patients with traumatic brain injury (TBI) with large contusions make up a specific TBI subtype. Because of the risk of brain edema worsening,…”
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Monitoring of Cerebral Blood Flow and Metabolism Bedside in Patients with Subarachnoid Hemorrhage - A Xenon-CT and Microdialysis Study by Rostami, Elham, Engquist, Henrik, Johnson, Ulf, Howells, Timothy, Ronne-Engström, Elisabeth, Nilsson, Pelle, Hillered, Lars, Lewén, Anders, Enblad, Per

“…Cerebral ischemia is the leading cause of morbidity and mortality following aneurysmal subarachnoid hemorrhage (SAH). Although 70% of the patients show…”
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Pre-injury antithrombotic agents predict intracranial hemorrhagic progression, but not worse clinical outcome in severe traumatic brain injury by Svedung Wettervik, Teodor, Lenell, Samuel, Enblad, Per, Lewén, Anders

“…Background The incidence of traumatic brain injury (TBI) patients of older age with comorbidities, who are pre-injury treated with antithrombotic agents…”
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