Search Results - "Lew, A. M."

Control of IBMIR in Neonatal Porcine Islet Xenotransplantation in Baboons by Hawthorne, W. J., Salvaris, E. J., Phillips, P., Hawkes, J., Liuwantara, D., Burns, H., Barlow, H., Stewart, A. B., Peirce, S. B., Hu, M., Lew, A. M., Robson, S. C., Nottle, M. B., D'Apice, A. J. F., O'Connell, P. J., Cowan, P. J.

“…The instant blood‐mediated inflammatory reaction (IBMIR) is a major obstacle to the engraftment of intraportal pig islet xenografts in primates. Higher…”
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Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune induction by Lew, A. M, Boyle, J. S, Brady, J. L

“…Viral infection and vaccination with DNA both induce similar immune responses to encoded antigens that are produced by the host,. The availability of antigens…”
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Local effector failure in mesothelioma is not mediated by CD4+ CD25+ T-regulator cells by Jackaman, C, Cornwall, S, Lew, A. M, Zhan, Y, Robinson, B. W. S, Nelson, D. J

“…The aim of the present study was to define the point at which mesothelioma T-cell responses fail in order to design better immunotherapies. A murine model of…”
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Shutdown of immunological priming and presentation after in vivo administration of adenovirus by Sutherland, R M, Londrigan, S L, Brady, J L, Azher, H, Carrington, E M, Zhan, Y, Vega-Ramos, J, Villadangos, J A, Lew, A M

“…Adenoviral (Adv) vectors are widely used in both experimental and clinical trials for vaccination and gene therapy. Recombinant Adv can evoke potent innate…”
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The Development, Maturation, and Turnover Rate of Mouse Spleen Dendritic Cell Populations by Kamath, Arun T, Pooley, Joanne, O'Keeffe, Meredith A, Vremec, David, Zhan, Yifan, Lew, Andrew M, D'Amico, Angela, Wu, Li, Tough, David F, Shortman, Ken

“…Three distinct subtypes of dendritic cells (DC) are present in mouse spleen, separable as CD4(-)8alpha(-), CD4(+)8alpha(-), and CD4(-)8alpha(+) DC. We have…”
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The need for IgG2c specific antiserum when isotyping antibodies from C57BL/6 and NOD mice by Martin, Roland M., Brady, Jamie L., Lew, Andrew M.

“…Isotyping and quantitation of murine IgG2a antibodies are widely performed with commercial monoclonal and polyclonal antisera raised against BALB/c IgG2a…”
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Generic construction of single component particles that elicit humoural and cellular immune responses without the need for adjuvants by White, P.J, Anastasopoulos, F, Church, J.E, Kuo, C.-Y, Boyd, B.J, Hickey, P.L.C, Tu, L. Sze, Burns, P, Lew, A.M, Heath, W.R, Davey, G.M, Pouton, C.W

“…Abstract Insoluble, pure protein particles could be advantageous as single-entity vaccines or as carriers for small peptide epitopes. Dense gas anti-solvent…”
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Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice by French, M. B., Allison, J., Cram, D. S., Thomas, H. E., Dempsey-Collier, M., Silva, A., Georgiou, H. M., Kay, T. W., Harrison, L. C., Lew, A. M.

“…Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice. M B French , J Allison , D S Cram , H E Thomas , M Dempsey-Collier ,…”
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The comparative efficacy of CTLA-4 and L-selectin targeted DNA vaccines in mice and sheep by Drew, Damien R., Boyle, J.S., Lew, A.M., Lightowlers, M.W., Chaplin, P.J., Strugnell, R.A.

“…The access of antigens to antigen presenting cells (APCs) appears to be a rate-limiting step in the generation of immune responses to DNA vaccines. The…”
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Ciprofloxacin versus trimethoprim/sulfamethoxazole for prophylaxis of bacterial infections in bone marrow transplant recipients: a randomized, controlled trial by Lew, M A, Kehoe, K, Ritz, J, Antman, K H, Nadler, L, Kalish, L A, Finberg, R

“…To compare the efficacy and safety of ciprofloxacin (CIP) and trimethoprim/sulfamethoxazole (TMS) for the prevention of bacterial infections in patients who…”
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Targeting Improves the Efficacy of a DNA Vaccine against Corynebacterium pseudotuberculosis in Sheep by CHAPLIN, P. J, DE ROSE, R, BOYLE, J. S, MCWATERS, P, KELLY, J, TENNENT, J. M, LEW, A. M, SCHEERLINCK, J.-P. Y

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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An inexpensive alternative to glassmilk for DNA purification by Boyle, J.S., Lew, A.M.

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Molecular Cloning of F4/80-Like-Receptor, a Seven-Span Membrane Protein Expressed Differentially by Dendritic Cell and Monocyte-Macrophage Subpopulations by Caminschi, Irina, Lucas, Karen M, O'Keeffe, Meredith A, Hochrein, Hubertus, Laabi, Yacine, Kontgen, Frank, Lew, Andrew M, Shortman, Ken, Wright, Mark D

“…A novel dendritic cell (DC) surface molecule termed F4/80-like-receptor (FIRE) has been selected based on its differential expression between DC subsets. The…”
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CD4 Help-Independent Induction of Cytotoxic CD8 Cells to Allogeneic P815 Tumor Cells Is Absolutely Dependent on Costimulation by Zhan, Yifan, Corbett, Alexandra J, Brady, Jamie L, Sutherland, Robyn M, Lew, Andrew M

“…Mice made transgenic (Tg) for a rat anti-mouse CD4 Ab (GK mice) represent a novel CD4-deficient model. They not only lack canonical CD4 cells in the periphery,…”
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Innate Immune Surveillance of Spontaneous B Cell Lymphomas by Natural Killer Cells and gamma delta T Cells by Street, SEA, Hayakawa, Y, Zhan, Y, Lew, A M, MacGregor, D, Jamieson, A M, Diefenbach, A, Yagita, H, Godfrey, DI, Smyth, MJ

“…Few studies have demonstrated that innate lymphocytes play a major role in preventing spontaneous tumor formation. We evaluated the development of spontaneous…”
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Without CD4 Help, CD8 Rejection of Pig Xenografts Requires CD28 Costimulation But Not Perforin Killing by Zhan, Yifan, Brady, Jamie L, Sutherland, Robyn M, Lew, Andrew M

“…Although CD4 cells are major mediators in cellular rejection of fetal pig pancreas (FPP) in the mouse, rejection still occurs in the absence of CD4 cells,…”
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Inhibitory control of prolactin and Pit-1 gene promoters by dopamine. Dual signaling pathways required for D2 receptor-regulated expression of the prolactin gene by ELSHOLTZ, H. P, LEW, A. M, ALBERT, P. R, SUNDMARK, V. C

“…Transcription of the prolactin gene is suppressed by dopaminergic activation of D2 receptors in pituitary lactotrophs. The mechanism of signal transduction at…”
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Secretion of a Malarial Histidine-Rich Protein (Pf HRP II) from Plasmodium falciparum-Infected Erythrocytes by Howard, Russell J., Uni, Shigehiko, Aikawa, Masamichi, Aley, Stephen B., Leech, James H., Lew, Andrew M., Wellems, Thomas E., Rener, Joan, Taylor, Diane W.

“…Plasmodium falciparum-infected erythrocytes (IRBCs) synthesize several histidine-rich proteins (HRPs) that accumulate high levels of [3 H]histidine but very…”
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Protective effect of CTLA4Ig secreted by transgenic fetal pancreas allografts by SUTHERLAND, R. M, BRADY, J. L, GEORGIOU, H. M, THOMAS, H. E, LEW, A. M

“…Pancreas allotransplantation offers a cure for insulin-dependent diabetes mellitus. Systemic immunosuppression used to prevent immune destruction of the graft…”
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Thy-1+ Dendritic Epidermal Cells Express T3 Antigen and the T-Cell Receptor γ Chain by Stingl, Georg, Koning, Frits, Yamada, Hidekazu, Yokoyama, Wayne M., Tschachler, Erwin, Bluestone, Jeffrey A., Steiner, Georg, Samelson, Lawrence E., Lew, Andrew M., Coligan, John E., Shevach, Ethan M.

“…The murine epidermis is a heterogeneous epithelium composed of keratinocytes, melanocytes, Langerhans cells, and a recently described subpopulation (2-3%) of…”
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