Search Results - "Levy, Yinon"

A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes by Noy-Porat, Tal, Makdasi, Efi, Alcalay, Ron, Mechaly, Adva, Levy, Yinon, Bercovich-Kinori, Adi, Zauberman, Ayelet, Tamir, Hadas, Yahalom-Ronen, Yfat, Israeli, Ma’ayan, Epstein, Eyal, Achdout, Hagit, Melamed, Sharon, Chitlaru, Theodor, Weiss, Shay, Peretz, Eldar, Rosen, Osnat, Paran, Nir, Yitzhaki, Shmuel, Shapira, Shmuel C., Israely, Tomer, Mazor, Ohad, Rosenfeld, Ronit

“…The novel highly transmissible human coronavirus SARS-CoV-2 is the causative agent of the COVID-19 pandemic. Thus far, there is no approved therapeutic drug…”
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Post-exposure protection of SARS-CoV-2 lethal infected K18-hACE2 transgenic mice by neutralizing human monoclonal antibody by Rosenfeld, Ronit, Noy-Porat, Tal, Mechaly, Adva, Makdasi, Efi, Levy, Yinon, Alcalay, Ron, Falach, Reut, Aftalion, Moshe, Epstein, Eyal, Gur, David, Chitlaru, Theodor, Vitner, Einat B., Melamed, Sharon, Politi, Boaz, Zauberman, Ayelet, Lazar, Shirley, Beth-Din, Adi, Evgy, Yentl, Yitzhaki, Shmuel, Shapira, Shmuel C., Israely, Tomer, Mazor, Ohad

“…The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), exhibits high levels of mortality…”
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Circumventing Y. pestis Virulence by Early Recruitment of Neutrophils to the Lungs during Pneumonic Plague by Vagima, Yaron, Zauberman, Ayelet, Levy, Yinon, Gur, David, Tidhar, Avital, Aftalion, Moshe, Shafferman, Avigdor, Mamroud, Emanuelle

“…Pneumonic plague is a fatal disease caused by Yersinia pestis that is associated with a delayed immune response in the lungs. Because neutrophils are the first…”
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Neutralizing Monoclonal Anti-SARS-CoV-2 Antibodies Isolated from Immunized Rabbits Define Novel Vulnerable Spike-Protein Epitope by Makdasi, Efi, Levy, Yinon, Alcalay, Ron, Noy-Porat, Tal, Zahavy, Eran, Mechaly, Adva, Epstein, Eyal, Peretz, Eldar, Cohen, Hila, Bar-On, Liat, Chitlaru, Theodor, Cohen, Ofer, Glinert, Itai, Achdout, Hagit, Israely, Tomer, Rosenfeld, Ronit, Mazor, Ohad

“…Monoclonal antibodies represent an important avenue for COVID-19 therapy and are routinely used for rapid and accessible diagnosis of SARS-CoV-2 infection. The…”
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Phage Therapy Potentiates Second-Line Antibiotic Treatment against Pneumonic Plague by Vagima, Yaron, Gur, David, Aftalion, Moshe, Moses, Sarit, Levy, Yinon, Makovitzki, Arik, Holtzman, Tzvi, Oren, Ziv, Segula, Yaniv, Fatelevich, Ella, Tidhar, Avital, Zauberman, Ayelet, Rotem, Shahar, Mamroud, Emanuelle, Steinberger-Levy, Ida

“…Plague pandemics and outbreaks have killed millions of people during the history of humankind. The disease, caused by the bacteria , is currently treated…”
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Influenza virus infection augments susceptibility to respiratory Yersinia pestis exposure and impacts the efficacy of antiplague antibiotic treatments by Vagima, Yaron, Gur, David, Erez, Noam, Achdout, Hagit, Aftalion, Moshe, Levy, Yinon, Zauberman, Ayelet, Tidhar, Avital, Gutman, Hila, Lazar, Shlomi, Israely, Tomer, Paran, Nir, Melamed, Sharon, Brosh-Nissimov, Tal, Chitlaru, Theodor, Sagi, Irit, Mamroud, Emanuelle

“…Various respiratory viral infections in general and seasonal influenza in particular may increase the susceptibility to bacterial infections. Plague caused by…”
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Rapid Induction of Protective Immunity against Pneumonic Plague by Yersinia pestis Polymeric F1 and LcrV Antigens by Aftalion, Moshe, Tidhar, Avital, Vagima, Yaron, Gur, David, Zauberman, Ayelet, Holtzman, Tzvi, Makovitzki, Arik, Chitlaru, Theodor, Mamroud, Emanuelle, Levy, Yinon

“…In a recent study, we demonstrated that vaccination with the polymeric F1 capsule antigen of the plague pathogen led to the rapid induction of a protective…”
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Disruption of the NlpD lipoprotein of the plague pathogen Yersinia pestis affects iron acquisition and the activity of the twin-arginine translocation system by Tidhar, Avital, Levy, Yinon, Zauberman, Ayelet, Vagima, Yaron, Gur, David, Aftalion, Moshe, Israeli, Ofir, Chitlaru, Theodor, Ariel, Naomi, Flashner, Yehuda, Zvi, Anat, Mamroud, Emanuelle

“…We have previously shown that the cell morphogenesis NlpD lipoprotein is essential for virulence of the plague bacteria, Yersinia pestis. To elucidate the role…”
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Host Iron Nutritional Immunity Induced by a Live Yersinia pestis Vaccine Strain Is Associated with Immediate Protection against Plague by Zauberman, Ayelet, Vagima, Yaron, Tidhar, Avital, Aftalion, Moshe, Gur, David, Rotem, Shahar, Chitlaru, Theodor, Levy, Yinon, Mamroud, Emanuelle

“…Prompt and effective elicitation of protective immunity is highly relevant for cases of rapidly deteriorating fatal diseases, such as plague, which is caused…”
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Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice by Noy-Porat, Tal, Mechaly, Adva, Levy, Yinon, Makdasi, Efi, Alcalay, Ron, Gur, David, Aftalion, Moshe, Falach, Reut, Leviatan Ben-Arye, Shani, Lazar, Shirley, Zauberman, Ayelet, Epstein, Eyal, Chitlaru, Theodor, Weiss, Shay, Achdout, Hagit, Edgeworth, Jonathan D., Kikkeri, Raghavendra, Yu, Hai, Chen, Xi, Yitzhaki, Shmuel, Shapira, Shmuel C., Padler-Karavani, Vered, Mazor, Ohad, Rosenfeld, Ronit

“…Neutralizing antibodies represent a valuable therapeutic approach to countermeasure the current COVID-19 pandemic. Emergence of SARS-CoV-2 variants emphasizes…”
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Inhalational Gentamicin Treatment Is Effective Against Pneumonic Plague in a Mouse Model by Gur, David, Glinert, Itai, Aftalion, Moshe, Vagima, Yaron, Levy, Yinon, Rotem, Shahar, Zauberman, Ayelet, Tidhar, Avital, Tal, Arnon, Maoz, Sharon, Ber, Raphael, Pass, Avi, Mamroud, Emanuelle

“…Pneumonic plague is an infectious disease characterized by rapid and fulminant development of acute pneumonia and septicemia that results in death within days…”
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Targeting of the Yersinia pestis F1 capsular antigen by innate-like B1b cells mediates a rapid protective response against bubonic plague by Levy, Yinon, Vagima, Yaron, Tidhar, Avital, Aftalion, Moshe, Gur, David, Nili, Uri, Chitlaru, Theodore, Zauberman, Ayelet, Mamroud, Emanuelle

“…The generation of adaptive immunity by vaccination is usually a prolonged process that requires multiple dosing over several months. Hence, vaccines are…”
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Immunodominant Linear B-Cell Epitopes of SARS-CoV-2 Spike, Identified by Sera from K18-hACE2 Mice Infected with the WT or Variant Viruses by Levy, Yinon, Alcalay, Ron, Zvi, Anat, Makdasi, Efi, Peretz, Eldar, Noy-Porat, Tal, Chitlaru, Theodor, Mandelboim, Michal, Mazor, Ohad, Rosenfeld, Ronit

“…SARS-CoV-2 surface spike protein mediates the viral entry into the host cell and represents the primary immunological target of COVID-19 vaccines as well as…”
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Fc-Independent Protection from SARS-CoV-2 Infection by Recombinant Human Monoclonal Antibodies by Noy-Porat, Tal, Edri, Avishay, Alcalay, Ron, Makdasi, Efi, Gur, David, Aftalion, Moshe, Evgy, Yentl, Beth-Din, Adi, Levy, Yinon, Epstein, Eyal, Radinsky, Olga, Zauberman, Ayelet, Lazar, Shirley, Yitzhaki, Shmuel, Marcus, Hadar, Porgador, Angel, Rosenfeld, Ronit, Mazor, Ohad

“…The use of passively-administered neutralizing antibodies is a promising approach for the prevention and treatment of SARS-CoV-2 infection. Antibody-mediated…”
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Yersinia pestis endowed with increased cytotoxicity is avirulent in a bubonic plague model and induces rapid protection against pneumonic plague by Zauberman, Ayelet, Tidhar, Avital, Levy, Yinon, Bar-Haim, Erez, Halperin, Gideon, Flashner, Yehuda, Cohen, Sara, Shafferman, Avigdor, Mamroud, Emanuelle

“…An important virulence strategy evolved by bacterial pathogens to overcome host defenses is the modulation of host cell death. Previous observations have…”
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Novel RNA Extraction Method for Dual RNA-seq Analysis of Pathogen and Host in the Early Stages of Yersinia pestis Pulmonary Infection by Israeli, Ofir, Cohen-Gihon, Inbar, Aftalion, Moshe, Gur, David, Vagima, Yaron, Zauberman, Ayelet, Levy, Yinon, Zvi, Anat, Chitlaru, Theodor, Mamroud, Emanuelle, Tidhar, Avital

“…Pneumonic plague, caused by Yersinia pestis, is a rapidly progressing lethal infection. The various phases of pneumonic plague are yet to be fully understood…”
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Epitope Binning of Novel Monoclonal Anti F1 and Anti LcrV Antibodies and Their Application in a Simple, Short, HTRF Test for Clinical Plague Detection by Mechaly, Adva, Vitner, Einat B, Levy, Yinon, Gur, David, Barlev-Gross, Moria, Sittner, Assa, Koren, Michal, Levy, Haim, Mamroud, Emanuelle, Fisher, Morly

“…Mouse monoclonal antibodies were raised against plague disease biomarkers: the bacterial capsular protein fraction 1 (F1) and the low-calcium response-LcrV…”
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YopP-expressing variant of Y. pestis activates a potent innate immune response affording cross-protection against yersiniosis and tularemia [corrected] by Zauberman, Ayelet, Flashner, Yehuda, Levy, Yinon, Vagima, Yaron, Tidhar, Avital, Cohen, Ofer, Bar-Haim, Erez, Gur, David, Aftalion, Moshe, Halperin, Gideon, Shafferman, Avigdor, Mamroud, Emanuelle

“…Plague, initiated by Yersinia pestis infection, is a rapidly progressing disease with a high mortality rate if not quickly treated. The existence of…”
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Leptin Induces Angiopoietin-2 Expression in Adipose Tissues by Cohen, Batya, Barkan, Dalit, Levy, Yinon, Goldberg, Iris, Fridman, Eduard, Kopolovic, Juri, Rubinstein, Menachem

“…Adipose tissues consisting of adipocytes, microvasculature, and stroma are completely ablated upon over-expression of leptin in rats. This tissue regression is…”
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Monitoring of Neutrophil Recruitment to Mice Lungs During Pneumonic Plague by Vagima, Yaron, Levy, Yinon, Mamroud, Emanuelle

“…Early sensing of bacterial infection and the immediate recruitment of neutrophils to the lung is a major and decisive stage of the innate immune response to…”
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