Search Results - "Levy, Orlie"
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1
Post-transcriptional Regulation of the Sodium/Iodide Symporter by Thyrotropin
Published in The Journal of biological chemistry (15-06-2001)“…The Na+/I−symporter (NIS) is a key plasma membrane glycoprotein that mediates active I− transport in the thyroid gland (Dai, G., Levy, O., and Carrasco, N…”
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2
Cloning and characterization of the thyroid iodide transporter
Published in Nature (London) (01-02-1996)“…Iodide (I-) is an essential constituent of the thyroid hormones T3 and T4, and is accumulated by the thyroid. The transport of iodide, the first step in…”
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Journal Article -
3
Molecular Analysis of the Sodium/Iodide Symporter: Impact on Thyroid and Extrathyroid Pathophysiology
Published in Physiological reviews (01-07-2000)“…Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York De la Vieja, Antonio, Orsolya Dohan, Orlie Levy, and Nancy Carrasco…”
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4
The mammary gland iodide transporter is expressed during lactation and in breast cancer
Published in Nature medicine (01-08-2000)“…The sodium/iodide symporter mediates active iodide transport in both healthy and cancerous thyroid tissue. By exploiting this activity, radioiodide has been…”
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5
The Paired-Domain Transcription Factor Pax8 Binds to the Upstream Enhancer of the Rat Sodium/Iodide Symporter Gene and Participates in Both Thyroid-Specific and Cyclic-AMP-Dependent Transcription
Published in Molecular and Cellular Biology (01-03-1999)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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6
Characterization of the Thyroid Na+/I- Symporter with an Anti-COOH Terminus Antibody
Published in Proceedings of the National Academy of Sciences - PNAS (27-05-1997)“…The Na+/I- symporter (NIS) is the plasma membrane protein that catalyzes active I- transport in the thyroid, the first step in thyroid hormone biogenesis. The…”
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Journal Article -
7
Thyroid Na+/I- symporter. Mechanism, stoichiometry, and specificity
Published in The Journal of biological chemistry (24-10-1997)“…The rat thyroid Na+/I- symporter (NIS) was expressed in Xenopus laevis oocytes and characterized using electrophysiological, tracer uptake, and electron…”
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Journal Article -
8
N-linked glycosylation of the thyroid Na+/I- symporter (NIS). Implications for its secondary structure model
Published in The Journal of biological chemistry (28-08-1998)“…The Na+/I- symporter (NIS), a 618-amino acid membrane glycoprotein that catalyzes the active accumulation of I- into thyroid cells, was identified and…”
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Journal Article -
9
The Na+/I- symporter (NIS): recent advances
Published in Journal of bioenergetics and biomembranes (01-04-1998)“…The Na+/I- symporter (NIS) catalyzes the accumulation of iodide into thyroid cells, an essential step in the biosynthesis of thyroid hormones. As a result of…”
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10
Crystal Structure of the Oligomerization Domain of NSP4 from Rotavirus Reveals a Core Metal-binding Site
Published in Journal of molecular biology (15-12-2000)“…During the maturation of rotaviral particles, non-structural protein 4 (NSP4) plays a critical role in the translocation of the immature capsid into the lumen…”
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11
Identification of a structural requirement for thyroid Na +/I − symporter (NIS) function from analysis of a mutation that causes human congenital hypothyroidism
Published in FEBS letters (05-06-1998)“…Patients with congenital lack of I − transport do not accumulate I − in their thyroids, often resulting in severe hypothyroidism. A single amino acid…”
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12
Na+-I-Symport Activity is Present in Membrane Vesicles from Thyrotropin-Deprived Non-I--Transporting Cultured Thyroid Cells
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-1994)“…The active accumulation of I-in the thyroid gland is mediated by the Na+-I-symporter and driven by the Na+gradient generated by the Na+/K+-ATPase. Thyrotropin…”
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13
N-linked Glycosylation of the Thyroid Na+/I− Symporter (NIS)
Published in The Journal of biological chemistry (28-08-1998)“…The Na+/I−symporter (NIS), a 618-amino acid membrane glycoprotein that catalyzes the active accumulation of I− into thyroid cells, was identified and…”
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Journal Article -
14
N-linked Glycosylation of the Thyroid Na+/Iâ Symporter (NIS)
Published in The Journal of biological chemistry (28-08-1998)“…The Na + /I â symporter (NIS), a 618-amino acid membrane glycoprotein that catalyzes the active accumulation of I â into thyroid cells, was identified and…”
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15
Thyroid Na+/Iâ Symporter
Published in The Journal of biological chemistry (24-10-1997)“…The rat thyroid Na + /I â symporter (NIS) was expressed in Xenopus laevis oocytes and characterized using electrophysiological, tracer uptake, and electron…”
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Journal Article -
16
Thyroid Na+/I− Symporter
Published in The Journal of biological chemistry (24-10-1997)“…The rat thyroid Na+/I− symporter (NIS) was expressed inXenopus laevis oocytes and characterized using electrophysiological, tracer uptake, and electron…”
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Journal Article -
17
Characterization of the iodide transport system of the thyroid gland and its hormonal regulation
Published 01-01-1995“…The thyroid is an endocrine gland that synthesizes the hormones tri-iodothyronine (T$\sb3$) and thyroxine (T$\sb4$). Production and release of these hormones…”
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Dissertation -
18
Inhibition of the Na + /I ‐ symporter by harmaline and 3‐amino‐1‐methyl‐5 H ‐pyrido(4,3‐b)indole acetate in thyroid cells and membrane vesicles
Published in European journal of biochemistry (01-08-1991)“…Novel inhibitors of the Na + /I − symporter were identified using rat‐thyroid‐derived FRTL‐5 cells and sealed vesicles from calf thyroid as model systems. Na +…”
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19
Inhibition of the Na+/I‐ symporter by harmaline and 3‐amino‐1‐methyl‐5H‐pyrido(4,3‐b)indole acetate in thyroid cells and membrane vesicles
Published in European journal of biochemistry (15-08-1991)“…Novel inhibitors of the Na+/I− symporter were identified using rat‐thyroid‐derived FRTL‐5 cells and sealed vesicles from calf thyroid as model systems…”
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