Search Results - "Levy, Olivier"
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APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration
Published in The Journal of neuroscience (07-10-2015)“…Contrary to Alzheimer's disease (AD), the APOE2 allele increases and the APOE4 allele reduces the risk to develop age-related macular degeneration (AMD)…”
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CCR2+ monocytes infiltrate atrophic lesions in age‐related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice
Published in EMBO molecular medicine (01-11-2013)“…Atrophic age‐related macular degeneration (AMD) is associated with the subretinal accumulation of mononuclear phagocytes (MPs). Their role in promoting or…”
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Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age‐related macular degeneration
Published in EMBO molecular medicine (01-02-2015)“…Physiologically, the retinal pigment epithelium (RPE) expresses immunosuppressive signals such as FAS ligand (FASL), which prevents the accumulation of…”
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TOX is a critical regulator of tumour-specific T cell differentiation
Published in Nature (London) (01-07-2019)“…Tumour-specific CD8 T cell dysfunction is a differentiation state that is distinct from the functional effector or memory T cell states 1 – 6 . Here we…”
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Efficient 5-OP-RU-Induced Enrichment of Mucosa-Associated Invariant T Cells in the Murine Lung Does Not Enhance Control of Aerosol Mycobacterium tuberculosis Infection
Published in Infection and immunity (15-12-2020)“…Mucosa-associated invariant T (MAIT) cells are an innate-like T cell subset in mammals that recognize microbial vitamin B metabolites presented by the…”
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Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation
Published in Immunity (Cambridge, Mass.) (21-02-2017)“…Variants of the CFH gene, encoding complement factor H (CFH), show strong association with age-related macular degeneration (AMD), a major cause of blindness…”
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Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration
Published in The Journal of neuroscience (06-05-2015)“…Photoreceptor degeneration in age-related macular degeneration (AMD) is associated with an infiltration and chronic accumulation of mononuclear phagocytes…”
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Interleukin-1β Inhibition Prevents Choroidal Neovascularization and Does Not Exacerbate Photoreceptor Degeneration
Published in The American journal of pathology (01-05-2011)“…The pro-inflammatory cytokine IL-1β has been shown to promote angiogenesis. It can have a neurotoxic or neuroprotective effect. Here, we have studied the…”
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The role of thymocyte selection-associated HMG box protein (TOX) in CD8 T cell differentiation and dysfunction
Published in The Journal of immunology (1950) (01-05-2018)“…Abstract CD8 T cells are powerful adaptive immune cells that specifically recognize infected cells and eliminate them. However, in the context of tumors,…”
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Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages
Published in Angiogenesis (London) (01-12-2012)“…Inflammatory neovascularization, such as choroidal neovascularization (CNV), occur in the presence of Notch expressing macrophages. DLL4s anti-angiogenic…”
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Erratum to: Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages
Published in Angiogenesis (London) (01-06-2013)Get full text
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Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages: DLL4's opposing effects in choroidal neovascularization
Published in Angiogenesis (London) (01-12-2012)“…Inflammatory neovascularization, such as choroidal neovascularization (CNV), occur in the presence of Notch expressing macrophages. DLL4s anti-angiogenic…”
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CCR 2 + monocytes infiltrate atrophic lesions in age‐related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice
Published in EMBO molecular medicine (01-11-2013)“…Atrophic age‐related macular degeneration (AMD) is associated with the subretinal accumulation of mononuclear phagocytes (MPs). Their role in promoting or…”
Get full text
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Les « Écoles historiques » à l'épreuve de Gabriel Monod Un historien célébré et méconnu
Published in Revue historique (01-10-2012)“…À l'occasion du centenaire de la mort de Gabriel Monod, cet article s'attache à éclairer le paradoxe apparent de sa fortune. Pour tous les récits autorisés de…”
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Les « Écoles historiques » à l'épreuve de Gabriel Monod. Un historien célébré et méconnu
Published in Revue historique (2012)“…RésuméÀ l’occasion du centenaire de la mort de Gabriel Monod, cet article s’attache à éclairer le paradoxe apparent de sa fortune. Pour tous les récits…”
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Proton pump inhibitors in general medicine. Comparison of routine practices with marketing authorization indications
Published in Gastroentérologie clinique et biologique (2007)“…To determine whether inaugural prescriptions for proton pump inhibitors (PPI) written by general practitioners in the Grenoble region are in non-compliance…”
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