Search Results - "Levy, Estrella"

Avelumab, an IgG1 anti-PD-L1 Immune Checkpoint Inhibitor, Triggers NK Cell-Mediated Cytotoxicity and Cytokine Production Against Triple Negative Breast Cancer Cells by Juliá, Estefanía Paula, Amante, Analía, Pampena, María Betina, Mordoh, José, Levy, Estrella Mariel

“…The standard treatment for Triple Negative Breast Cancer (TNBC) patients is cytotoxic chemotherapy, but it is restricted since the duration of response is…”
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Targeting ADCC: A different approach to HER2 breast cancer in the immunotherapy era by Mandó, Pablo, Rivero, Sergio G., Rizzo, Manglio M., Pinkasz, Marina, Levy, Estrella M.

“…The clinical outcome of patients with human epidermal growth factor receptor 2 (HER2) amplified breast carcinoma (BC) has improved with the development of…”
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Natural Killer Cells in Human Cancer : From Biological Functions to Clinical Applications by Levy, Estrella Mariel, Roberti, María Paula, Mordoh, José

“…Natural killer (NK) cells are central components of the innate immunity. In murine models, it has been shown that NK cells can control both local tumor growth…”
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Phenotypic and Functional Dysregulated Blood NK Cells in Colorectal Cancer Patients Can Be Activated by Cetuximab Plus IL-2 or IL-15 by Rocca, Yamila Sol, Roberti, María Paula, Juliá, Estefanía Paula, Pampena, María Betina, Bruno, Luisina, Rivero, Sergio, Huertas, Eduardo, Sánchez Loria, Fernando, Pairola, Alejandro, Caignard, Anne, Mordoh, José, Levy, Estrella Mariel

“…The clinical outcome of colorectal cancer (CRC) is associated with the immune response; thus, these tumors could be responsive to different immune therapy…”
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Peripheral changes in immune cell populations and soluble mediators after anti-PD-1 therapy in non-small cell lung cancer and renal cell carcinoma patients by Juliá, Estefanía Paula, Mandó, Pablo, Rizzo, Manglio Miguel, Cueto, Gerardo Rubén, Tsou, Florencia, Luca, Romina, Pupareli, Carmen, Bravo, Alicia Inés, Astorino, Walter, Mordoh, José, Martín, Claudio, Levy, Estrella Mariel

“…Patients with non-small cell lung cancer (NSCLC) and renal cell carcinoma (RCC) have shown benefit from anti-PD-1 therapies. However, not all patients…”
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Cetuximab and IL-15 Promote NK and Dendritic Cell Activation In Vitro in Triple Negative Breast Cancer by Juliá, Estefanía Paula, Mordoh, José, Levy, Estrella Mariel

“…Triple Negative Breast Cancer (TNBC) treatment is still challenging, and immunotherapy is a potential approach in this tumor subtype. Cetuximab is an IgG1…”
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Natural killer cells as helper cells in dendritic cell cancer vaccines by Pampena, María Betina, Levy, Estrella Mariel

“…Vaccine-based cancer immunotherapy has generated highly variable clinical results due to differing methods of vaccine preparation and variation in patient…”
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Phenotypic and functional analysis in HER2+ targeted therapy of human NK cell subpopulation according to the expression of FcεRIγ and NKG2C in breast cancer patients by Bordignon, María B., Pesce Viglietti, Ayelén I., Juliá, Estefanía P., Sanchez, María B., Rölle, Alexander, Mandó, Pablo, Sabatini, Luciana, Ostinelli, Alexis, Rizzo, Manglio M., Barrio, María M., Mordoh, José, Fainboim, Leonardo, Levy, Estrella M.

“…Adaptive NK cells constitute an NK cell subpopulation, which expands after human cytomegalovirus (HCMV) infection. This subpopulation has stronger production…”
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Metallothionein expression in colorectal cancer: relevance of different isoforms for tumor progression and patient survival by Arriaga, Juan Martín, MSc, Levy, Estrella Mariel, PhD, Bravo, Alicia Inés, MD, Bayo, Sergio Morales, MD, Amat, Mora, MD, Aris, Mariana, MSc, Hannois, Adrián, MD, Bruno, Luisina, MD, Roberti, María Paula, MSc, Loria, Fernando Sánchez, MD, Pairola, Alejandro, MD, Huertas, Eduardo, MD, Mordoh, José, MD, PhD, Bianchini, Michele, PhD

“…Summary Metallothioneins are a family of small, cysteine-rich proteins with many functions. Immunohistochemical evaluation of all metallothionein 1 + 2…”
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Syngeneic B16-F1 cells are more efficient than allogeneic Cloudman cells as antigen source in DC-based vaccination in the B16-F1 murine melanoma model by Mac Keon, Soledad, Bentivegna, Sofía, Levy, Estrella M., Marks, Michael S., Mantegazza, Adriana R., Wainstok, Rosa, Mordoh, José

“…A major obstacle to obtaining relevant results in cancer vaccination has been the lack of identification of immunogenic antigens. Dendritic cell (DC)-based…”
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Altered phenotype in peripheral blood and tumor-associated NK cells from colorectal cancer patients by Rocca, Yamila S, Roberti, María P, Arriaga, Juan M, Amat, Mora, Bruno, Luisina, Pampena, María B, Huertas, Eduardo, Loria, Fernando Sánchez, Pairola, Alejandro, Bianchini, Michele, Mordoh, José, Levy, Estrella M

“…Despite NK cells being originally identified because of their ability to kill tumor cells in vitro, only limited information is available on NK cells…”
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Dissecting the Immune Stimulation Promoted by CSF-470 Vaccine Plus Adjuvants in Cutaneous Melanoma Patients: Long Term Antitumor Immunity and Short Term Release of Acute Inflammatory Reactants by Pampena, María B, Cartar, Holliday C, Cueto, Gerardo Rubén, Levy, Estrella M, Blanco, Paula A, Barrio, María M, Mordoh, José

“…As cutaneous melanoma (CM) currently remains with a bleak prognosis, thorough investigation of new treatment options are of utmost relevance. In the phase…”
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Changes in the TCRβ Repertoire and Tumor Immune Signature From a Cutaneous Melanoma Patient Immunized With the CSF-470 Vaccine: A Case Report by Aris, Mariana, Bravo, Alicia Inés, Pampena, María Betina, Blanco, Paula Alejandra, Carri, Ibel, Koile, Daniel, Yankilevich, Patricio, Levy, Estrella Mariel, Barrio, María Marcela, Mordoh, José

“…The allogeneic therapeutic vaccine CSF-470 has demonstrated a significant benefit over medium-dose IFNα2b in the distant metastasis-free survival for stages…”
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Overexpression of CD85j in TNBC patients inhibits Cetuximab‐mediated NK‐cell ADCC but can be restored with CD85j functional blockade by Roberti, María P., Juliá, Estefanía P., Rocca, Yamila S., Amat, Mora, Bravo, Alicia I., Loza, José, Coló, Federico, Loza, Carlos M., Fabiano, Verónica, Maino, Mercedes, Podhorzer, Ariel, Fainboim, Leonardo, Barrio, María M., Mordoh, José, Levy, Estrella M.

“…Clinical studies suggest that triple negative breast cancer (TNBC) patients with epidermal growth factor receptor (EGFR)‐expressing tumors could benefit from…”
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Phase II Study of Adjuvant Immunotherapy with the CSF-470 Vaccine Plus Bacillus Calmette-Guerin Plus Recombinant Human Granulocyte Macrophage-Colony Stimulating Factor vs Medium-Dose Interferon Alpha 2B in Stages IIB, IIC, and III Cutaneous Melanoma Patients: A Single Institution, Randomized Study by Mordoh, José, Pampena, María Betina, Aris, Mariana, Blanco, Paula Alejandra, Lombardo, Mónica, von Euw, Erika María, Mac Keon, Soledad, Yépez Crow, Michelle, Bravo, Alicia Inés, O'Connor, Juan Manuel, Orlando, Ana Gabriela, Ramello, Franco, Levy, Estrella Mariel, Barrio, María Marcela

“…The irradiated, allogeneic, cellular CSF-470 vaccine plus Bacillus Calmette-Guerin (BCG) and recombinant human granulocyte macrophage-colony stimulating factor…”
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Biological role of NK cells and immunotherapeutic approaches in breast cancer by Roberti, María P, Mordoh, José, Levy, Estrella M

“…In recent decades, tumor surveillance by the immune system and its impact on disease outcomes in cancer patients in general and in breast cancer (BC) patients…”
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Protein expression changes during human triple negative breast cancer cell line progression to lymph node metastasis in a xenografted model in nude mice by Roberti, María Paula, Arriaga, Juan Martín, Bianchini, Michele, Quintá, Héctor Ramiro, Bravo, Alicia Inés, Levy, Estrella Mariel, Mordoh, José, Barrio, María Marcela

“…Triple negative breast cancers (TNBC) lacking hormone receptors and HER-2 amplification are very aggressive tumors. Since relevant differences between primary…”
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Lack of Prognostic Value of Pretreatment Neutrophil-to-Lymphocyte Ratio in Early Breast Cancer by Sifón, Maria del Rosario, Marcolini, Nicolas, Barber, Maria Julia, Mclean, Ignacio, Rizzo, Manglio, Rivero, Sergio, Costanzo, Maria Victoria, Nervo, Adrian, Crimi, Gabriel, Perazzo, Florencia, Levy, Estrella Mariel, Mandó, Pablo

“…Background: Breast cancer is a highly heterogeneous disease with large differences in the risk of recurrence. An elevated neutrophil-to-lymphocyte ratio (NLR)…”
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High neutrophil to lymphocyte ratio and decreased CD69 + NK cells represent a phenotype of high risk in early-stage breast cancer patients by Mandó, Pablo, Rizzo, Manglio, Roberti, María Paula, Juliá, Estefanía Paula, Pampena, María Betina, Pérez de la Puente, Constanza, Loza, Carlos Martín, Ponce, Carolina, Nadal, Jorge, Coló, Federico Andres, Mordoh, José, Levy, Estrella Mariel

“…Breast cancer (BC) is a highly heterogeneous disease presenting a broad range of clinical and molecular characteristics. In the past years, a growing body of…”
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Editorial: "Cancer Immunotherapy: Lights and Shadows" by Barrio, María Marcela, Levy, Estrella Mariel, Mordoh, José

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