Search Results - "Levy, E"

Advancements in Next-Generation Sequencing by Levy, Shawn E, Myers, Richard M

“…The term next-generation sequencing is almost a decade old, but it remains the colloquial way to describe highly parallel or high-output sequencing methods…”
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Fast and sensitive taxonomic assignment to metagenomic contigs by Mirdita, M, Steinegger, M, Breitwieser, F, Söding, J, Levy Karin, E

“…MMseqs2 taxonomy is a new tool to assign taxonomic labels to metagenomic contigs. It extracts all possible protein fragments from each contig, quickly retains…”
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Constitutive Type I Interferon Modulates Homeostatic Balance through Tonic Signaling by Gough, Daniel J., Messina, Nicole L., Clarke, Christopher J.P., Johnstone, Ricky W., Levy, David E.

“…Interferons (IFNs) were discovered as cytokines induced during and protecting from viral infection. They have been documented to play essential roles in…”
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Accuracy of Autism Screening in a Large Pediatric Network by Guthrie, Whitney, Wallis, Kate, Bennett, Amanda, Brooks, Elizabeth, Dudley, Jesse, Gerdes, Marsha, Pandey, Juhi, Levy, Susan E, Schultz, Robert T, Miller, Judith S

“…Universal screening is recommended to reduce the age of diagnosis for autism spectrum disorder (ASD). However, there are insufficient data on children who…”
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Mapping soil moisture across the UK: assimilating cosmic-ray neutron sensors, remotely sensed indices, rainfall radar and catchment water balance data in a Bayesian hierarchical model by Levy, Peter E

“…Soil moisture is important in many hydrological and ecological processes. However, data sets which are currently available have issues with accuracy and…”
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The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformation by Gough, Daniel J, Koetz, Lisa, Levy, David E

“…Activating mutations in the RasGTPases are the most common oncogenic lesions in human cancer. Similarly, elevated STAT3 expression and/or phosphorylation are…”
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International retrospective study of the pipeline embolization device: a multicenter aneurysm treatment study by Kallmes, D F, Hanel, R, Lopes, D, Boccardi, E, Bonafé, A, Cekirge, S, Fiorella, D, Jabbour, P, Levy, E, McDougall, C, Siddiqui, A, Szikora, I, Woo, H, Albuquerque, F, Bozorgchami, H, Dashti, S R, Delgado Almandoz, J E, Kelly, M E, Turner, 4th, R, Woodward, B K, Brinjikji, W, Lanzino, G, Lylyk, P

“…Flow diverters are increasingly used in the endovascular treatment of intracranial aneurysms. Our aim was to determine neurologic complication rates following…”
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A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells by Littman, Dan R, Manel, Nicolas, Hogstad, Brandon, Wang, Yaming, Levy, David E, Unutmaz, Derya

“…Dendritic cells serve a key function in host defence, linking innate detection of microbes to activation of pathogen-specific adaptive immune responses…”
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The Development and Validation of a New Machiavellianism Scale by Dahling, Jason J., Whitaker, Brian G., Levy, Paul E.

“…A new measure of Machiavellianism, the Machiavellian Personality Scale (MPS), was developed and validated over two studies. Machiavellianism is conceptualized…”
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Knockout of a difficult‐to‐remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations by Chiu, Josephine, Valente, Kristin N., Levy, Nicholas E., Min, Lie, Lenhoff, Abraham M., Lee, Kelvin H.

“…ABSTRACT While the majority of host cell protein (HCP) impurities are effectively removed in typical downstream purification processes, a small population of…”
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Mitochondrial STAT3 Supports Ras-Dependent Oncogenic Transformation by Gough, Daniel J, Corlett, Alicia, Schlessinger, Karni, Wegrzyn, Joanna, Larner, Andrew C, Levy, David E

“…Signal transducer and activator of transcription 3 (STAT3) is a latent cytoplasmic transcription factor responsive to cytokine signaling and tyrosine kinase…”
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Cancer risks among BRCA1 and BRCA2 mutation carriers by LEVY-LAHAD, E, FRIEDMAN, E

“…BRCA1 and BRCA2 mutations increase breast and ovarian cancer risks substantially enough to warrant risk reduction surgery, despite variable risk estimates…”
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Risk reduction and screening of cancer in hereditary breast-ovarian cancer syndromes: ESMO Clinical Practice Guideline by Sessa, C., Balmaña, J., Bober, S.L., Cardoso, M.J., Colombo, N., Curigliano, G., Domchek, S.M., Evans, D.G., Fischerova, D., Harbeck, N., Kuhl, C., Lemley, B., Levy-Lahad, E., Lambertini, M., Ledermann, J.A., Loibl, S., Phillips, K.-A., Paluch-Shimon, S.

“…•It provides recommendations for risk reduction and screening in hereditary breast and ovarian cancer syndrome.•It focuses on risk reduction and screening…”
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Corporate social responsibility: perspectives of hotel frontline employees by Park, Sun-Young, E. Levy, Stuart

“…Purpose – The aim of this paper is to examine hotel frontline employees' perceptions of corporate social responsibility (CSR) activities at the hotel they…”
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The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor by Powell, Anne E., Wang, Yang, Li, Yina, Poulin, Emily J., Means, Anna L., Washington, Mary K., Higginbotham, James N., Juchheim, Alwin, Prasad, Nripesh, Levy, Shawn E., Guo, Yan, Shyr, Yu, Aronow, Bruce J., Haigis, Kevin M., Franklin, Jeffrey L., Coffey, Robert J.

“…Lineage mapping has identified both proliferative and quiescent intestinal stem cells, but the molecular circuitry controlling stem cell quiescence is…”
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Evidence for a weakening relationship between interannual temperature variability and northern vegetation activity by Piao, Shilong, Nan, Huijuan, Huntingford, Chris, Ciais, Philippe, Friedlingstein, Pierre, Sitch, Stephen, Peng, Shushi, Ahlström, Anders, Canadell, Josep G., Cong, Nan, Levis, Sam, Levy, Peter E., Liu, Lingli, Lomas, Mark R., Mao, Jiafu, Myneni, Ranga B., Peylin, Philippe, Poulter, Ben, Shi, Xiaoying, Yin, Guodong, Viovy, Nicolas, Wang, Tao, Wang, Xuhui, Zaehle, Soenke, Zeng, Ning, Zeng, Zhenzhong, Chen, Anping

“…Satellite-derived Normalized Difference Vegetation Index (NDVI), a proxy of vegetation productivity, is known to be correlated with temperature in northern…”
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Autism by Levy, Susan E, Prof, Mandell, David S, ScD, Schultz, Robert T, Prof

“…Summary Autism spectrum disorders are characterised by severe deficits in socialisation, communication, and repetitive or unusual behaviours. Increases over…”
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The Relationship between Perceptions of Organizational Politics and Employee Attitudes, Strain, and Behavior: A Meta-Analytic Examination by Chang, Chu-hsiang, Rosen, Christopher C., Levy, Paul E.

“…The current study tested a model that links perceptions of organizational politics to job performance and "turnover intentions" (intentions to quit)…”
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STAT3 Plays a Critical Role in KRAS-Induced Pancreatic Tumorigenesis by CORCORAN, Ryan B, CONTINO, Gianmarco, DESHPANDE, Vikram, TZATSOS, Alexandros, CONRAD, Claudius, BENES, Cyril H, LEVY, David E, SETTLEMAN, Jeffrey, ENGELMAN, Jeffrey A, BARDEESY, Nabeel

“…The STAT3 transcription factor is an important regulator of stem cell self-renewal, cancer cell survival, and inflammation. In the pancreas, STAT3 is…”
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Applications of proteomic methods for CHO host cell protein characterization in biopharmaceutical manufacturing by Valente, Kristin N, Levy, Nicholas E, Lee, Kelvin H, Lenhoff, Abraham M

“…Chinese hamster ovary (CHO) cells are the most prevalent host organism for production of recombinant therapeutic proteins, including monoclonal antibodies…”
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