Search Results - "Levisetti, Matteo G."

Weak Proinsulin Peptide–Major Histocompatibility Complexes Are Targeted in Autoimmune Diabetes in Mice by Levisetti, Matteo G, Lewis, Danna M, Suri, Anish, Unanue, Emil R

“…Weak Proinsulin Peptide–Major Histocompatibility Complexes Are Targeted in Autoimmune Diabetes in Mice Matteo G. Levisetti 1 2 , Danna M. Lewis 1 , Anish Suri…”
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Absence of Lymph Nodes in NOD Mice Treated With Lymphotoxin-β Receptor Immunoglobulin Protects From Diabetes by LEVISETTI, Matteo G, SURI, Anish, FREDERICK, Katherine, UNANUE, Emil R

“…Absence of Lymph Nodes in NOD Mice Treated With Lymphotoxin-β Receptor Immunoglobulin Protects From Diabetes Matteo G. Levisetti 1 2 , Anish Suri 2 , Katherine…”
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Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes by Unanue, Emil R, Mohan, James F, Calderon, Boris, Herzog, Jeremy W, Levisetti, Matteo G, Petzold, Shirley J

“…The immunological mechanisms of diabetes onset in NOD mice are poorly characterized. Unanue and co-workers find that insulin peptide–reactive (but not insulin…”
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The Insulin-Specific T Cells of Nonobese Diabetic Mice Recognize a Weak MHC-Binding Segment in More Than One Form by Levisetti, Matteo G, Suri, Anish, Petzold, Shirley J, Unanue, Emil R

“…Several naturally occurring anti-insulin CD4 T cells were isolated from islet infiltrates of NOD mice. In accordance with the results of others, these T cells…”
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Identification of naturally processed peptides bound to the class I MHC molecule H‐2Kd of normal and TAP‐deficient cells by Suri, Anish, Walters, James J., Levisetti, Matteo G., Gross, Michael L., Unanue, Emil R.

“…This report details the biochemical features of natural peptides selected by the H‐2Kd class I MHC molecule. In normal cell lines, the length of the naturally…”
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Autoantibodies and CD4 T cells target a β cell retroviral envelope protein in non‐obese diabetic mice by Levisetti, Matteo G., Suri, Anish, Vidavsky, Ilan, Gross, Michael L., Kanagawa, Osami, Unanue, Emil R.

“…We determined that, over a biologic time interval, from 4 to 8 weeks of age, female non‐obese diabetic (NOD) mice develop antibodies against pancreatic…”
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Do the peptide-binding properties of diabetogenic class II molecules explain autoreactivity? by Suri, Anish, Levisetti, Matteo G, Unanue, Emil R

“…One seminal aspect in autoimmune diabetes is antigen presentation of beta cell antigens by the diabetes-propensity class II histocompatibility molecules. The…”
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Non-Obese Diabetic Mice Rapidly Develop Dramatic Sympathetic Neuritic Dystrophy: A New Experimental Model of Diabetic Autonomic Neuropathy by Schmidt, Robert E, Dorsey, Denise A, Beaudet, Lucie N, Frederick, Kathy E, Parvin, Curtis A, Plurad, Santiago B, Levisetti, Matteo G

“…To address the pathogenesis of diabetic autonomic neuropathy, we have examined the sympathetic nervous system in non-obese diabetic (NOD) and streptozotocin…”
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Diabetic pancreatic β cells ARNT all they should be by Levisetti, Matteo G., Polonsky, Kenneth S.

“…A complex network of interacting transcription factors plays a critical role in normal pancreatic β cell function, with mutations in certain transcription…”
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Non-Obese Diabetic Mice Rapidly Develop Dramatic Sympathetic Neuritic Dystrophy by Schmidt, Robert E., Dorsey, Denise A., Beaudet, Lucie N., Frederick, Kathy E., Parvin, Curtis A., Plurad, Santiago B., Levisetti, Matteo G.

“…To address the pathogenesis of diabetic autonomic neuropathy, we have examined the sympathetic nervous system in non-obese diabetic (NOD) and streptozotocin…”
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INDUCTION, MAINTENANCE, AND REVERSAL OF STREPTOZOTOCIN-INDUCED INSULIN-DEPENDENT DIABETES MELLITUS IN THE JUVENILE CYNOMOLGUS MONKEY (Macaca fascilularis)1 by Theriault, Betty R., Thistlethwaite, J. R., Levisetti, Matteo G., Wardrip, Craig L., Szot, Gregory, Bruce, David S., Rilo, Horatio, Li, Xiantang, Gray, Gary S., Bluestone, Jeffrey A., Padrid, Philip A.

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In Autoimmune Diabetes Unique Autoreactive T Cells Recognize Insulin Peptides Generated in the Islets of Langerhans by Mohan, James F., Levisetti, Matteo G., Calderon, Boris, Herzog, Jeremy W., Petzold, Shirley J., Unanue, Emil R.

“…Besides the genetic framework, there are two critical requirements for the development of tissue-specific autoimmune diseases. First, autoreactive T cells need…”
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Immunosuppressive effects of human CTLA4Ig in a non-human primate model of allogeneic pancreatic islet transplantation by Levisetti, MG, Padrid, PA, Szot, GL, Mittal, N, Meehan, SM, Wardrip, CL, Gray, GS, Bruce, DS, Thistlethwaite, JR, Jr, Bluestone, JA

“…Ag-specific T cell activation requires a CD28-mediated costimulatory interaction. This observation has suggested novel approaches to suppress donor-specific…”
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Weak Proinsulin Peptide-Major Histocompatibility Complexes Are Targeted in Autoimmune Diabetes in Mice. Commentary by JAMES, Eddie A, KWOK, William W, LEVISETTI, Matteo G, LEWIS, Danna M, SURI, Anish, UNANUE, Emil R

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Absence of lymph nodes in NOD mice treated with Lymphotoxin-[beta] receptor immunoglobulin protects from diabetes by Levisetti, Matteo G, Suri, Anish, Frederick, Katherine, Unanue, Emil R

“…Pregnant nonobese diabetic (NOD) mice were treated with lymphotoxin-[beta] receptor immunoglobulin fusion protein (LT[beta]R-Ig) or control human…”
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Identification of naturally processed peptides bound to the class I MHC molecule H‐2K d of normal and TAP‐deficient cells by Suri, Anish, Walters, James J., Levisetti, Matteo G., Gross, Michael L., Unanue, Emil R.

“…Abstract This report details the biochemical features of natural peptides selected by the H‐2K d class I MHC molecule. In normal cell lines, the length of the…”
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Identification of naturally processed peptides bound to the class I MHC molecule H-2K super(d) of normal and TAP-deficient cells by Suri, Anish, Walters, James J, Levisetti, Matteo G, Gross, Michael L, Unanue, Emil R

“…This report details the biochemical features of natural peptides selected by the H-2Kd class I MHC molecule. In normal cell lines, the length of the naturally…”
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Autoantibodies and CD4 T cells target a   cell retroviral envelope protein in non-obese diabetic mice by Levisetti, M. G.

“…We determined that, over a biologic time interval, from 4 to 8 weeks of age, female non-obese diabetic (NOD) mice develop antibodies against pancreatic…”
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Induction, maintenance, and reversal of streptozotocin-induced insulin-dependent diabetes mellitus in the juvenile cynomolgus monkey (Macaca fascilularis) by THERIAULT, B. R, THISTLETHWAITE, J. R, PADRID, P. A, LEVISETTI, M. G, WARDRIP, C. L, SZOT, G, BRUCE, D. S, RILO, H, XIANTANGLI, GRAY, G. S, BLUESTONE, J. A

“…Insulin-dependent diabetes mellitus (IDDM) is the second most prevalent chronic illness of children. Investigation of the treatment of IDDM is hindered by the…”
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