Search Results - "Levine, Orin"
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Systematic evaluation of serotypes causing invasive pneumococcal disease among children under five: the pneumococcal global serotype project
Published in PLoS medicine (01-10-2010)“…Approximately 800,000 children die each year due to pneumococcal disease and >90% of these deaths occur in developing countries where few children have access…”
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Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates
Published in The Lancet (British edition) (12-09-2009)“…Summary Background Streptococcus pneumoniae is a leading cause of bacterial pneumonia, meningitis, and sepsis in children worldwide. However, many countries…”
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Serotype-specific changes in invasive pneumococcal disease after pneumococcal conjugate vaccine introduction: a pooled analysis of multiple surveillance sites
Published in PLoS medicine (01-09-2013)“…Vaccine-serotype (VT) invasive pneumococcal disease (IPD) rates declined substantially following introduction of 7-valent pneumococcal conjugate vaccine (PCV7)…”
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Effect of the introduction of pneumococcal conjugate vaccination on invasive pneumococcal disease in The Gambia: a population-based surveillance study
Published in The Lancet infectious diseases (01-06-2016)“…Summary Background Little information is available about the effect of pneumococcal conjugate vaccines (PCVs) in low-income countries. We measured the effect…”
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Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimates
Published in The Lancet (British edition) (12-09-2009)“…Summary Background Haemophilus influenzae type b (Hib) is a leading cause of childhood bacterial meningitis, pneumonia, and other serious infections. Hib…”
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What drivers will influence global immunizations in the era of grand convergence in global health?
Published in Vaccine (20-01-2017)“…Abstract Recent projections suggest that by 2035 global health will look dramatically different than it does today. In what’s called a ‘grand convergence’ the…”
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Cost-effectiveness and economic benefits of vaccines in low- and middle-income countries: A systematic review
Published in Vaccine (17-12-2012)“…Highlights ► Reviews the economic benefits of adult and childhood vaccines in developing countries. ► Identified 108 articles from 51 countries covering 23…”
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Mobile phone-delivered reminders and incentives to improve childhood immunisation coverage and timeliness in Kenya (M-SIMU): a cluster randomised controlled trial
Published in The Lancet global health (01-04-2017)“…Summary Background As mobile phone access continues to expand globally, opportunities exist to leverage these technologies to support demand for immunisation…”
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Computerized lung sound analysis as diagnostic aid for the detection of abnormal lung sounds: A systematic review and meta-analysis
Published in Respiratory medicine (01-09-2011)“…Summary Rationale The standardized use of a stethoscope for chest auscultation in clinical research is limited by its inherent inter-listener variability…”
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Effect of ten-valent pneumococcal conjugate vaccine on invasive pneumococcal disease and nasopharyngeal carriage in Kenya: a longitudinal surveillance study
Published in The Lancet (British edition) (25-05-2019)“…Ten-valent pneumococcal conjugate vaccine (PCV10), delivered at 6, 10, and 14 weeks of age was introduced in Kenya in January, 2011, accompanied by a catch-up…”
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Sequelae due to bacterial meningitis among African children: a systematic literature review
Published in BMC medicine (14-09-2009)“…African children have some of the highest rates of bacterial meningitis in the world. Bacterial meningitis in Africa is associated with high case fatality and…”
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Addressing the persistent inequities in immunization coverage
Published in Bulletin of the World Health Organization (01-02-2020)“…A key focus of the health-related sustainable development goal (SDG) 3 is universal health coverage (UHC), including access to safe, effective, quality, and…”
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The Definition of Pneumonia, the Assessment of Severity, and Clinical Standardization in the Pneumonia Etiology Research for Child Health Study
Published in Clinical infectious diseases (01-04-2012)“…To develop a case definition for the Pneumonia Etiology Research for Child Health (PERCH) project, we sought a widely acceptable classification that was linked…”
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Association of C-Reactive Protein With Bacterial and Respiratory Syncytial Virus–Associated Pneumonia Among Children Aged <5 Years in the PERCH Study
Published in Clinical infectious diseases (15-06-2017)“…Background. Lack of a gold standard for identifying bacterial and viral etiologies of pneumonia has limited evaluation of C-reactive protein (CRP) for…”
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Impact of the introduction of pneumococcal conjugate vaccination on pneumonia in The Gambia: population-based surveillance and case-control studies
Published in The Lancet infectious diseases (01-09-2017)“…Summary Background Pneumococcal conjugate vaccines (PCVs) are used in many low-income countries but their impact on the incidence of pneumonia is unclear. The…”
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Factors predicting mortality in hospitalised HIV-negative children with lower-chest-wall indrawing pneumonia and implications for management
Published in PloS one (11-03-2024)“…In 2012, the World Health Organization revised treatment guidelines for childhood pneumonia with lower chest wall indrawing (LCWI) but no 'danger signs', to…”
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Density of Upper Respiratory Colonization With Streptococcus pneumoniae and Its Role in the Diagnosis of Pneumococcal Pneumonia Among Children Aged <5 Years in the PERCH Study
Published in Clinical infectious diseases (15-06-2017)“…Background. Previous studies suggested an association between upper airway pneumococcal colonization density and pneumococcal pneumonia, but data in children…”
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The Effect of Antibiotic Exposure and Specimen Volume on the Detection of Bacterial Pathogens in Children With Pneumonia
Published in Clinical infectious diseases (15-06-2017)“…Background. Antibiotic exposure and specimen volume are known to affect pathogen detection by culture. Here we assess their effects on bacterial pathogen…”
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Impact of the introduction of pneumococcal conjugate vaccination on invasive pneumococcal disease and pneumonia in The Gambia: 10 years of population-based surveillance
Published in The Lancet infectious diseases (01-09-2021)“…The Gambia introduced seven-valent pneumococcal conjugate vaccine (PCV7) in August 2009, followed by PCV13 in May, 2011, using a schedule of three primary…”
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Is Higher Viral Load in the Upper Respiratory Tract Associated With Severe Pneumonia? Findings From the PERCH Study
Published in Clinical infectious diseases (15-06-2017)“…Background. The etiologic inference of identifying a pathogen in the upper respiratory tract (URT) of children with pneumonia is unclear. To determine if viral…”
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