Search Results - "Levin, M C"

The utility of MRI in suspected MS: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology by FROHMAN, E. M, GOODIN, D. S, KACHUCK, N. J, LEVIN, M. C, PHILLIPS, J. T, RACKE, M. K, RIVERA, V. M, STUART, W. H, CALABRESI, P. A, CORBOY, J. R, COYLE, P. K, FILIPPI, M, FRANK, J. A, GALETTA, S. L, GROSSMAN, R. I, HAWKER, K

“…Advancements in imaging technologies and newly evolving treatments offer the promise of more effective management strategies for MS. Until recently,…”
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Evaluation of macrophage-specific promoters using lentiviral delivery in mice by Levin, M C, Lidberg, U, Jirholt, P, Adiels, M, Wramstedt, A, Gustafsson, K, Greaves, D R, Li, S, Fazio, S, Linton, M F, Olofsson, S-O, Borén, J, Gjertsson, I

“…In gene therapy, tissue-specific promoters are useful tools to direct transgene expression and improve efficiency and safety. Macrophage-specific promoters…”
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Molecular mimicry in neurological disease: what is the evidence by Lee, S, Levin, M. C

“…Autoimmune diseases are a leading cause of disability and are increasing in incidence in industrialized countries. How people develop autoimmune diseases is…”
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Phase 1 trial of transforming growth factor beta 2 in chronic progressive MS by CALABRESI, P. A, FIELDS, N. S, MCFARLAND, H. F, RACKE, M. K, MALONI, H. W, HANHAM, A, CARLINO, J, MOORE, J, LEVIN, M. C, DHIB-JALBUT, S, TRANQUILL, L. R, AUSTIN, H

“…Transforming growth factor (TGF)-beta2 is a pleiotropic cytokine associated with remissions in multiple sclerosis (MS) and amelioration of allergic…”
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Autoimmunity due to molecular mimicry as a cause of neurological disease by Levin, Michael C, Lee, Sang Min, Kalume, Franck, Morcos, Yvette, Dohan, F. Curtis, Hasty, Karen A, Callaway, Joseph C, Zunt, Joseph, Desiderio, Dominic M, Stuart, John M

“…One hypothesis that couples infection with autoimmune disease is molecular mimicry. Molecular mimicry is characterized by an immune response to an…”
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IgG in brain correlates with clinicopathological damage in HTLV-1 associated neurologic disease by JERNIGAN, M, MORCOS, Y, LEE, S. M, DOHAN, F. C, RAINE, C, LEVIN, M. C

“…To test the authors' hypothesis that antibody deposition in autopsy specimens from patients with human T-lymphotropic virus type 1-associated…”
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HTLV-1 induced molecular mimicry in neurological disease by Lee, S M, Morcos, Y, Jang, H, Stuart, J M, Levin, M C

“…As a model for molecular mimicry, we study patients infected with human T-lymphotropic virus type 1 (HTLV-1) who develop a neurological disease called…”
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Detection of human T-lymphotropic virus type I (HTLV-I) tax RNA in the central nervous system of HTLV-I-associated myelopathy/tropical spastic paraparesis patients by in situ hybridization by Lehky, T J, Fox, C H, Koenig, S, Levin, M C, Flerlage, N, Izumo, S, Sato, E, Raine, C S, Osame, M, Jacobson, S

“…Autopsy specimens from 3 patients with human T-lymphotropic virus (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) were examined for the…”
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Neuronal molecular mimicry in immune-mediated neurologic disease by Levin, M C, Krichavsky, M, Berk, J, Foley, S, Rosenfeld, M, Dalmau, J, Chang, G, Posner, J B, Jacobson, S

“…Molecular mimicry is implicated in the pathogenesis of autoimmune diseases such as diabetes mellitus, rheumatoid arthritis, and multiple sclerosis (MS)…”
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Reduction in HTLV-I proviral load and spontaneous lymphoproliferation in HTLV-I-associated myelopathy/tropical spastic paraparesis patients treated with humanized anti-Tac by Lehky, T J, Levin, M C, Kubota, R, Bamford, R N, Flerlage, A N, Soldan, S S, Leist, T P, Xavier, A, White, J D, Brown, M, Fleisher, T A, Top, L E, Light, S, McFarland, H F, Waldmann, T A, Jacobson, S

“…Human T-lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neurological disease that results from an…”
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Organization of galanin-immunoreactive inputs to the paraventricular nucleus with special reference to their relationship to catecholaminergic afferents by Levin, M C, Sawchenko, P E, Howe, P R, Bloom, S R, Polak, J M

“…Immunohistochemical and axonal transport techniques were used to characterize the origin and distribution of galanin-immunoreactive inputs to the…”
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Immunologic Analysis of a Spinal Cord–Biopsy Specimen from a Patient with Human T-Cell Lymphotropic Virus Type I–Associated Neurologic Disease by Levin, Michael C, Lehky, Tanya J, Flerlage, Alfred N, Katz, David, Kingma, Douglas W, Jaffe, Elaine S, Heiss, John D, Patronas, Nicholas, McFarland, Henry F, Jacobson, Steven

“…Human T-cell lymphotropic virus type I (HTLV-I) is associated with adult T-cell leukemia and a chronic progressive neurologic disease, HTLV-I–associated…”
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Pearls & Oy-sters: "Not multiple sclerosis" and the changing face of HTLV-1: A case report of downbeat nystagmus by Beeravolu, L R, Frohman, E M, Frohman, T C, Remington, G M, Lee, S, Levin, M C

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HTLV-1 and Its Neurological Complications by Khan, Raja B., Bertorini, Tulio E., Levin, Michael C.

“…BACKGROUND—Since its discovery in 1980, human T-cell lymphotropic virus type-1 (HTLV-1) has been associated with a number of neurological diseases. The…”
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Localization of retrovirus in the central nervous system of a patient co-infected with HTLV-1 and HIV with HAM/TSP and HIV-associated dementia by Michael C Levin, Marc K Rosenblum, Cecil H Fox, Steven Jacobson

“…Persons co-infected with HTLV-1 and HIV are at increased risk for neurologic disease. These patients may develop HAM/TSP and/or HIV-associated dementia. In…”
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HTLV-I/II Seroindeterminate Western Blot Reactivity in a Cohort of Patients with Neurological Disease by Soldan, Samantha S., Graf, Michael D., Waziri, Allen, Flerlage, Alfred N., Robinson, Susan M., Kawanishi, Taketo, Leist, Thomas P., Lehky, Tanya J., Levin, Michael C., Jacobson, Steven

“…The human T-cell lymphotropic virus type I (HTLV-I) is associated with a chronic, progressive neurological disease known as HTLV-I—associated…”
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PCR-in situ hybridization detection of human T-cell lymphotropic virus type 1 (HTLV-1) tax proviral DNA in peripheral blood lymphocytes of patients with HTLV-1-associated neurologic disease by Levin, M C, Fox, R J, Lehky, T, Walter, M, Fox, C H, Flerlage, N, Bamford, R, Jacobson, S

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Extensive latent retroviral infection in bone marrow of patients with HTLV-I-associated neurologic disease by Levin, M C, Krichavsky, M, Fox, R J, Lehky, T, Jacobson, S, Fox, C, Kleghorn, F, White, J, Young, N, Edwards, R J, Jack, N E, Bartholomew, C

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Neuropeptide co-expression in the magnocellular neurosecretory system of the female rat: evidence for differential modulation by estrogen by Levin, M C, Sawchenko, P E

“…Single- and double-immunohistochemical staining methods were used to assay the effect of estrogen on the expression of co-existing peptides in the…”
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Cross-Reactivity between Immunodominant Human T Lymphotropic Virus Type I tax and Neurons: Implications for Molecular Mimicry by Levin, Michael C., Lee, Sang Min, Morcos, Yvette, Brady, John, Stuart, John

“…Human T lymphotropic virus type I (HTLV-I)–associated myelopathy/tropical spastic paraparesis (HAM/TSP) is associated with immunoreactivity to HTLV-I tax…”
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