Search Results - "Levin, EG"

Demonstration of Single Chain Urokinase-Type Plasminogen Activator on Human Platelet Membrane by Park, Seonyang, Harker, Laurence A., Marzec, Ulla M., Levin, Eugene G.

“…Fibrinolytic activity was found to be associated with sonicated platelet membranes after separation from cytosol by differential centrifugation. This…”
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Quantitation and Properties of the Active and Latent Plasminogen Activator Inhibitors in Cultures of Human Endothelial Cells by Levin, Eugene G.

“…Human endothelial cells release two forms of a plasminogen activator-specific inhibitor: an active form that readily binds to and inhibits plasminogen…”
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Conversion of the Active to Latent Plasminogen Activator Inhibitor From Human Endothelial Cells by Levin, Eugene G., Santell, Lydia

“…The plasminogen activator inhibitor from human endothelial cells (PAI-1) exists in two forms in the culture medium: an active form that binds to and…”
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Cancer therapy through control of cell migration by Levin, Eugene G

“…Cell migration plays a pivotal role in a many biological process that are essential for development, repair, and pathogenesis. Thus, inhibition of migration…”
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Heat shock protein 27 kDa expression and phosphorylation regulates endothelial cell migration by Piotrowicz, Randolph S., Hickey, Eileen, Levin, Eugene G.

“…The effects of enhanced HSP27 expression or expression of a nonphosphorylatable form of HSP27 on the migration of bovine arterial endothelial cells was…”
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Suppression of Tumor Growth and Angiogenesis in Vivo by a Truncated Form of 24-kd Fibroblast Growth Factor (FGF)-2 by Levin, Eugene G., Sikora, Lyudmila, Ding, Lan, Rao, Savita P., Sriramarao, P.

“…Efforts to treat tumors have routinely depended on disruption of cell proliferation by a variety of methods, many involving stimulation of apoptosis. We have…”
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The expression of endothelial tissue plasminogen activator in vivo: a function defined by vessel size and anatomic location by Levin, E G, Santell, L, Osborn, K G

“…Plasma tissue plasminogen activator (tPA) has long been considered to be the product of the endothelial cells that line the various parts of the vascular…”
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Basolateral Membrane-associated 27-kDa Heat Shock Protein and Microfilament Polymerization by Piotrowicz, Randolph S., Levin, Eugene G.

“…The in vivo activity of the 27-kDa heat shock protein, a barbed-end microfilament capping protein, may be localized to the plasma membrane. To investigate this…”
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A potential basis for the thrombotic risks associated with lipoprotein( a ) by Miles, Lindsey A, Fless, Gunther M, Levin, Eugene G, Scanu, Angelo M, Plow, Edward F

“…Lipoprotein(a) (Lp(a)) has been strongly linked with atherosclerosis and is an independent risk factor for myocardial infarction. Distinguishing Lp(a) from…”
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Stimulation of tissue plasminogen activator production by retinoic acid: synergistic effect on protein kinase C-mediated activation by Medh, RD, Santell, L, Levin, EG

“…Trans retinoic acid (t-RA) stimulated the production of tissue plasminogen activator (tPA) in HeLa-S3 and human umbilical vein endothelial cells (huvecs) in a…”
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NF1 regulatory element functions as a repressor of tissue plasminogen activator expression by PHAM, Nhat-Long, FRANZEN, Amy, LEVIN, Eugene G

“…Analysis of the distribution of endothelial cell tissue plasminogen activator (tPA) in the vasculature of rodents and primates demonstrated that tPA is…”
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Localization of tissue plasminogen activator in the endothelium of a limited number of vessels by Levin, EG, del Zoppo, GJ

“…The immunolocalization of tissue plasminogen activator (tPA) was assessed in vessels of various sizes from baboons. Femoral artery and vein, carotid artery,…”
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The 27-kDa Heat Shock Protein Facilitates Basic Fibroblast Growth Factor Release from Endothelial Cells by Piotrowicz, Randolph S., Martin, Jody L., Dillman, Wolfgang H., Levin, Eugene G.

“…Basic fibroblast growth factor is an important mitogenic and angiogenic factor that stimulates endothelial cell growth and migration. This hormone is not…”
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Inhibition of Cell Migration by 24-kDa Fibroblast Growth Factor-2 Is Dependent upon the Estrogen Receptor by Piotrowicz, Randolph S., Ding, Lan, Maher, Pamela, Levin, Eugene G.

“…The single-copy gene for fibroblast growth factor-2 (FGF-2) encodes for multiple forms of the protein with molecular masses of 24, 22.5, 22, and 18 kDa. We…”
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Local abnormalities in coagulation and fibrinolytic pathways predispose to alveolar fibrin deposition in the adult respiratory distress syndrome by IDELL, S, JAMES, K. K, LEVIN, E. G, SCHWARTZ, B. S, MANCHANDA, N, MAUNDER, R. J, MARTIN, T. R, MCLARTY, J, FAIR, D. S

“…To determine the possible mechanism(s) promoting alveolar fibrin deposition in the adult respiratory distress syndrome (ARDS), we investigated the initiation…”
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Quantitation and properties of the active and latent plasminogen activator inhibitors in cultures of human endothelial cells by Levin, EG

“…Human endothelial cells release two forms of a plasminogen activator- specific inhibitor: an active form that readily binds to and inhibits plasminogen…”
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Latent Tissue Plasminogen Activator Produced by Human Endothelial Cells in Culture: Evidence for an Enzyme-Inhibitor Complex by Levin, Eugene G.

“…Conditioned medium from cultures of human umbilical vein endothelial cells was analyzed for the presence of tissue plasminogen activator (tPA) and urokinase…”
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Cyclic AMP potentiates phorbol ester stimulation of tissue plasminogen activator release and inhibits secretion of plasminogen activator inhibitor-1 from human endothelial cells by Santell, L, Levin, E G

“…We have examined the effect of phorbol esters and cAMP elevating compounds on tissue plasminogen activator (tPA) and plasminogen activator inhibitor-1 (PAI-1)…”
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Dual activities of 22-24 kda basic fibroblast growth factor: Inhibition of migration and stimulation of proliferation by Piotrowicz, Randolph S., Maher, Pamela A., Levin, Eugene G.

“…Basic fibroblast growth factor (FGF2) is synthesized as four isoforms with molecular weights of 24, 22.5, 22, and 18 kDa, with each of the three higher…”
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Progressive and Transient Expression of Tissue Plasminogen Activator During Fetal Development by Levin, Eugene G, Banka, Carole L, Parry, Graham C. N

“…In previous studies of the role of tissue plasminogen activator (tPA) in the lung inflammatory response, we observed that tPA expression was present…”
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