Search Results - "Levin, Brooke"

WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation by Xu, Mingang, Horrell, Jeremy, Snitow, Melinda, Cui, Jiawei, Gochnauer, Heather, Syrett, Camille M., Kallish, Staci, Seykora, John T., Liu, Fei, Gaillard, Dany, Katz, Jonathan P., Kaestner, Klaus H., Levin, Brooke, Mansfield, Corinne, Douglas, Jennifer E., Cowart, Beverly J., Tordoff, Michael, Liu, Fang, Zhu, Xuming, Barlow, Linda A., Rubin, Adam I., McGrath, John A., Morrisey, Edward E., Chu, Emily Y., Millar, Sarah E.

“…Human WNT10A mutations are associated with developmental tooth abnormalities and adolescent onset of a broad range of ectodermal defects. Here we show that…”
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A multicenter study of clinical impact of variant of uncertain significance reclassification in breast, ovarian and colorectal cancer susceptibility genes by Makhnoon, Sukh, Levin, Brooke, Ensinger, Megan, Mattie, Kristin, Volk, Robert J., Zhao, Zhongming, Mendoza, Tito, Shete, Sanjay, Samiian, Laila, Grana, Generosa, Grainger, Andrew, Arun, Banu, Shirts, Brian H., Peterson, Susan K.

“…Background Clinical interpretation of genetic test results is complicated by variants of uncertain significance (VUS) that have an unknown impact on health but…”
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A case of ovarian endometrioid adenocarcinoma with yolk sac differentiation and Lynch syndrome by Sookram, Janhvi, Levin, Brooke, Barroeta, Julieta, Kenley, Kathy, Mehta, Pallav, Krill, Lauren S.

“…Ovarian endometrioid adenocarcinoma with yolk sac component has been reported in fewer than twenty cases in the literature. A majority of the diagnoses are…”
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MTHFR: Addressing Genetic Counseling Dilemmas Using Evidence-Based Literature by Levin, Brooke Levenseller, Varga, Elizabeth

“…The 5, 10 methylenetetrahydrofolate reductase (MTHFR) enzyme is a catalyst in the folate metabolism pathway, the byproducts of which are involved in the…”
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Single-center comparison of cancer genetics referral rates for patients with pancreatic cancer following implementation of a best practice advisory: A quality improvement project by Rivera Morales, Stephanie, Dale, Ian, Mattie, Kristin, Levin, Brooke, Morrison, Jamin C., Jenab-Wolcott, Jenia

“…311 Background: Despite guidelines recommending germline genetic testing (GT) and genetic counseling for individuals with pancreatic ductal adenocarcinoma…”
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Use of breast surveillance between women with pathogenic variants and variants of uncertain significance in breast cancer susceptibility genes by Makhnoon, Sukh, Chen, Minxing, Levin, Brooke, Ensinger, Megan, Mattie, Kristin D., Grana, Generosa, Shete, Sanjay, Arun, Banu K., Peterson, Susan K.

“…Background Use of surveillance mammography and magnetic resonance imaging (MRI) has been understudied among women with variant of uncertain significance (VUS)…”
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Uptake of cancer risk management strategies among women who undergo cascade genetic testing for breast cancer susceptibility genes by Makhnoon, Sukh, Tran, Grace, Levin, Brooke, Mattie, Kristin D., Dreyer, Brian, Volk, Robert J., Grana, Generosa, Arun, Banu K., Peterson, Susan K.

“…Background Uptake of cancer risk management based on inherited predispositions, which encompasses bilateral mastectomy (BLM), bilateral salpingo‐oophorectomy…”
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A multicenter study of clinical impact of variant of uncertain significance reclassification in breast, ovarian, and colorectal cancer susceptibility genes by Makhnoon, Sukh, Levin, Brooke, Ensinger, Megan, Mattie, Kristin, Volk, Robert Joseph, Zhao, Zhongming, Mendoza, Tito R., Shete, Sanjay, Samiian, Laila, Grana, Generosa, Grainger, Andrew V., Arun, Banu, Shirts, Brian, Peterson, Susan K.

“…10512 Background: Up to 10% of all cancers are attributable to germline mutations and identifying mutation carriers is critical for cancer prevention. Clinical…”
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A Rare TP53 Mutation Predominant in Ashkenazi Jews Confers Risk of Multiple Cancers by Powers, Jacquelyn, Pinto, Emilia M, Barnoud, Thibaut, Leung, Jessica C, Martynyuk, Tetyana, Kossenkov, Andrew V, Philips, Aaron H, Desai, Heena, Hausler, Ryan, Kelly, Gregory, Le, Anh N, Li, Marilyn M, MacFarland, Suzanne P, Pyle, Louise C, Zelley, Kristin, Nathanson, Katherine L, Domchek, Susan M, Slavin, Thomas P, Weitzel, Jeffrey N, Stopfer, Jill E, Garber, Judy E, Joseph, Vijai, Offit, Kenneth, Dolinsky, Jill S, Gutierrez, Stephanie, McGoldrick, Kelly, Couch, Fergus J, Levin, Brooke, Edelman, Morris C, Levy, Carolyn Fein, Spunt, Sheri L, Kriwacki, Richard W, Zambetti, Gerard P, Ribeiro, Raul C, Murphy, Maureen E, Maxwell, Kara N

“…Germline mutations in cause a rare high penetrance cancer syndrome, Li-Fraumeni syndrome (LFS). Here, we identified a rare tetramerization domain missense…”
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Abstract P6-02-04: Use of breast surveillance between women with pathogenic variants and variants of uncertain significance in breast cancer susceptibility genes by Makhnoon, Sukh, Chen, Minxing, Levin, Brooke, Ensinger, Megan, Mattie, Kristin, Grana, Generosa, Shete, Sanjay, Arun, Banu K., Peterson, Susan K.

“…Abstract Background: Surveillance is a fundamental tool in the early detection and secondary prevention of many cancers. For women at increased genetic risk of…”
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Outcomes of the "BRCA Quality Improvement Dissemination Program": An initiative to improve patient receipt of cancer genetics services at five health systems by Bednar, Erica M., Chen, Minxing, Walsh, Michael T., Eppolito, Amanda L., Klein, Molly H., Teed, Kelly, Hodge, Brittany, Hunter, Jordan, Chao, Han Gill, Davis, Dillon, Serchion, Wilshauna, Yobbi, Cara, Krukenberg, Rebekah, Jenkinson, Sandra B., Moore, Jennifer J., Garcia, Cassandra, Gonzalez, Fatimaeliza, Murray, Towanna, Nielsen, Linda D., Ho, Brenda, Haas, Megan, Greenzweig, Sarah B., Anderson, Abby, Johnson, Christina, Morman, Nichole A., Bowdish, Elizabeth, Wise, Emaline, Cooper, Julia N., Russ, Pauline Kefalas, Tondo-Steele, Katelyn, de Gracia, Buonarotti F., Levin, Brooke, Mattie, Kristin, Zarnawski, Kathryn, Kalasinski, Molly, Stone, Jennifer, O'Brien, Caitlin, Bream, Alexa, Kennedy, Aidan M., Paul, Rachel A., Bilbao, Michelle, Romero, Maureen, Carr, Rebecca L., Siettmann, Jennifer M., Vercruyssen, Anna K., Leon, Kaycee, Arun, Banu K., Grainger, Andrew V., Warshal, David P., Bowman, Erin, Goedde, Timothy A., Halaharvi, Deepa, Rath, Kellie, Grana, Generosa, Mina, Lida, Lu, Karen H.

“…A quality improvement initiative (QII) was conducted with five community-based health systems' oncology care centers (sites A–E). The QII aimed to increase…”
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Implementation and outcome evaluations of a multi‐site improvement program in cancer genetics by Bednar, Erica M., Harper, Blake, Walsh, Michael T., Rechis, Ruth, Bilbao, Michelle, Carr, Rebecca L., Eppolito, Amanda L., Goedde, Timothy, Levin, Brooke, Mattie, Kristin, Morman, Nichole A., Rath, Kellie, Russ, Pauline, Siettmann, Jennifer M., Warshal, David, Wise, Emaline, Yobbi, Cara, Lu, Karen H.

“…Program evaluation can identify the successes and challenges of implementing clinical programs, which can inform future dissemination efforts. A cancer…”
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eP291 - Expanding the genotypic and phenotypic spectrum in a diverse cohort of 104 individuals with Wiedemann-Steiner Syndrome by Campbell, Ian, Harr, Margaret, Gold, Nina, Li, Dong, Bjornsson, Hans, Cohen, Julie, Fahrner, Jill, Fatemi, Ali, Harris, Jacqueline, Nowak, Catherine, Stevens, Cathy, Grand, Katheryn, Au, Margaret, Graham, John, Sanchez-Lara, Pedro, Del Campo, Miguel, Jones, Marilyn, Abdul-Rahman, Omar, Alkuraya, Fowzan, Bassetti, Jennifer, Bergstrom, Katherine, Bhoj, Elizabeth, Dugan, Sarah, Kaplan, Julie, Derar, Nada, Gripp, Karen W., Hauser, Natalie, Innes, Micheil, Keena, Beth, Kodra, Neslida, Miller, Rebecca, Nelson, Beverly, Nowaczyk, Malgorzata, Rahbeeni, Zuhair, Ben-Shachar, Shay, Shieh, Joseph, Slavotinek, Anne, Sobering, Andrew, Abbott, Mary-Alice, Allain, Dawn, Amlie-Wolf, Louise, Billie Au, Ping Yee, Bedoukian, Emma, Beek, Geoffrey, Barry, James, Berg, Janet, Bernstein, Jonathan, Cytrynbaum, Cheryl, Chung, Brian Hon-Yin, Donoghue, Sarah, Dorrani, Naghmeh, Eaton, Alison, Flores-Daboub, Josue, Dubbs, Holly, Felix, Carolyn, Fong, Chin-To, Fung, Jasmine Lee-Fong, Gangaram, Balram, Goldstein, Amy, Greenberg, Rotem, Ha, Thoa, Hersh, Joseph, Izumi, Kosuke, Kallish, Staci, Kwok, Pui-Yan, Jobling, Rebekah, Knight-Johnson, Amy, Kushner, Jessica, Lee, Bo Hoon, Levin, Brooke, Lindstrom, Kristin, Manickam, Kandamurugu, Mardach, Rebecca, McCormick, Elizabeth, McLeod, D. Ross, Mentch, Frank, Minks, Kelly, Muraresku, Colleen, Nelson, Stanley, Porazzi, Patrizia, Pichurin, Pavel, Powell-Hamilton, Nina, Powis, Zoe, Ritter, Alyssa, Rohena, Luis, Ronspies, Carey, Schroeder, Audrey, Stark, Zornitza, Starr, Lois, Stoler, Joan, Suwannarat, Pim, Velinov, Milen, Weksberg, Rosanna, Wilnai, Yael, Zadeh, Neda, Zand, Dina, Falk, Marni, Hakonarson, Hakon, Zackai, Elaine, Quintero-Rivera, Fabiola

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Expanding the genotypic and phenotypic spectrum in a diverse cohort of 104 individuals with Wiedemann-Steiner Syndrome by Sheppard, Sarah, Campbell, Ian, Harr, Margaret, Gold, Nina, Li, Dong, Bjornsson, Hans, Cohen, Julie, Fahrner, Jill, Fatemi, Ali, Harris, Jacqueline, Nowak, Catherine, Stevens, Cathy, Grand, Katheryn, Au, Margaret, Graham, John, Sanchez-Lara, Pedro, Del Campo, Miguel, Jones, Marilyn, Abdul-Rahman, Omar, Alkuraya, Fowzan, Bassetti, Jennifer, Bergstrom, Katherine, Bhoj, Elizabeth, Dugan, Sarah, Kaplan, Julie, Derar, Nada, Gripp, Karen W., Hauser, Natalie, Innes, Micheil, Keena, Beth, Kodra, Neslida, Miller, Rebecca, Nelson, Beverly, Nowaczyk, Malgorzata, Rahbeeni, Zuhair, Ben-Shachar, Shay, Shieh, Joseph, Slavotinek, Anne, Sobering, Andrew, Abbott, Mary-Alice, Allain, Dawn, Amlie-Wolf, Louise, Billie Au, Ping Yee, Bedoukian, Emma, Beek, Geoffrey, Barry, James, Berg, Janet, Bernstein, Jonathan, Cytrynbaum, Cheryl, Chung, Brian Hon-Yin, Donoghue, Sarah, Dorrani, Naghmeh, Eaton, Alison, Flores-Daboub, Josue, Dubbs, Holly, Felix, Carolyn, Fong, Chin-To, Fung, Jasmine Lee-Fong, Gangaram, Balram, Goldstein, Amy, Greenberg, Rotem, Ha, Thoa, Hersh, Joseph, Izumi, Kosuke, Kallish, Staci, Kravets, Elijah, Kwok, Pui-Yan, Jobling, Rebekah, Knight-Johnson, Amy, Kushner, Jessica, Lee, Bo Hoon, Levin, Brooke, Lindstrom, Kristin, Manickam, Kandamurugu, Mardach, Rebecca, McCormick, Elizabeth, McLeod, D. Ross, Mentch, Frank, Minks, Kelly, Muraresku, Colleen, Nelson, Stanley, Porazzi, Patrizia, Pichurin, Pavel, Powell-Hamilton, Nina, Powis, Zoe, Ritter, Alyssa, Rogers, Caleb, Rohena, Luis, Ronspies, Carey, Schroeder, Audrey, Stark, Zornitza, Starr, Lois, Stoler, Joan, Suwannarat, Pim, Velinov, Milen, Weksberg, Rosanna, Wilnai, Yael, Zadeh, Neda, Zand, Dina, Falk, Marni

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Success of referral to genetic counseling after positive lynch syndrome screening test by Irons, Robin F., Contino, Krysta M., Horte, Janice J., Levin, Brooke, Mattie, Kristin D., Wight, Margaret, Kwiatt, Michael E., Behling, Kathryn C., Edmonston, Tina B., McClane, Steven J.

“…Purpose Lynch syndrome (LS) is a hereditary condition that increases one’s risk of developing colorectal, endometrial, and other extracolonic cancers. MD…”
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A case of ovarian endometrioid adenocarcinoma with yolk sac differentiation and Lynch syndrome by Sookram, Janhvi, Levin, Brooke, Barroeta, Julieta, Kenley, Kathy, Mehta, Pallav, Krill, Lauren S

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