Search Results - "Levi, Laura I"
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Dicer-2-Dependent Generation of Viral DNA from Defective Genomes of RNA Viruses Modulates Antiviral Immunity in Insects
Published in Cell host & microbe (14-03-2018)“…The RNAi pathway confers antiviral immunity in insects. Virus-specific siRNA responses are amplified via the reverse transcription of viral RNA to viral DNA…”
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Arthritogenic Alphaviruses: A Worldwide Emerging Threat?
Published in Microorganisms (Basel) (14-05-2019)“…Arthritogenic alphaviruses are responsible for a dengue-like syndrome associated with severe debilitating polyarthralgia that can persist for months or years…”
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Host nutritional status affects alphavirus virulence, transmission, and evolution
Published in PLoS pathogens (11-11-2019)“…Malnourishment, specifically overweight/obesity and undernourishment, affects more than 2.5 billion people worldwide, with the number affected ever-increasing…”
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Defective viral genomes from chikungunya virus are broad-spectrum antivirals and prevent virus dissemination in mosquitoes
Published in PLoS pathogens (01-02-2021)“…Defective viral genomes (DVGs) are truncated and/or rearranged viral genomes produced during virus replication. Described in many RNA virus families, some of…”
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Chikungunya Virus RNA Secondary Structures Impact Defective Viral Genome Production
Published in Microorganisms (Basel) (29-08-2024)“…Chikungunya virus (CHIKV) is a mosquito-borne RNA virus that poses an emerging threat to humans. In a manner similar to other RNA viruses, CHIKV encodes an…”
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Cutaneous diphtheria: three case-reports to discuss determinants of re-emergence in resource-rich settings
Published in Emerging microbes & infections (01-01-2021)“…Diphtheria is a re-emerging disease in resource-rich settings. We here report three cases of cutaneous diphtheria diagnosed and managed in our infectious…”
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Vocal fold bamboo nodes in undifferentiated connective tissue disease
Published in Rheumatology (Oxford, England) (01-11-2014)Get full text
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Introduction of Objective Structured Clinical Examinations (OSCEs) in France: A paradigm shift in Medical Education
Published in Bulletin du cancer (01-11-2024)Get full text
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Cytomegalovirus (CMV) Viremia in People With Human Immunodeficiency Virus (HIV): Should We Treat the CMV? or the HIV? or Both?
Published in Clinical infectious diseases (21-03-2023)“…Abstract Cytomegalovirus (CMV) viremia in persons with human immunodeficiency virus (HIV) reflects the level of immunodeficiency. In the absence of CMV…”
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The defective component of viral populations
Published in Current opinion in virology (01-12-2018)“…•Defective interfering particles are particles containing degenerate forms of the virus genomes that are non-replicative per se, but remain infectious by…”
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Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds
Published in PLoS pathogens (01-10-2010)“…In a screen for RNA mutagen resistance, we isolated a high fidelity RNA dependent RNA polymerase (RdRp) variant of Coxsackie virus B3 (CVB3). Curiously, this…”
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Convalescent plasma improves overall survival in patients with B-cell lymphoid malignancy and COVID-19: a longitudinal cohort and propensity score analysis
Published in Leukemia (01-04-2022)“…Patients with hematological malignancy and COVID-19 display a high mortality rate. In such patients, immunosuppression due to underlying disease and previous…”
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Investigation of a Mycobacterium fortuitum catheter-related bloodstream infection in an oncology unit
Published in Infection control and hospital epidemiology (01-08-2023)“…We describe a case of healthcare-associated bloodstream infection due to Mycobacterium fortuitum. Whole-genome sequencing showed that the same strain was…”
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Cytomegalovirus viremia and risk of disease progression and death in HIV-positive patients starting antiretroviral therapy
Published in AIDS (London) (15-07-2022)“…The aim of this study was to assess the prevalence of cytomegalovirus (CMV) viremia in HIV-positive patients starting antiretroviral therapy (ART) and to…”
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Chikungunya Virus Vaccine Candidates with Decreased Mutational Robustness Are Attenuated In Vivo and Have Compromised Transmissibility
Published in Journal of virology (15-09-2019)“…Chikungunya virus (CHIKV) is a reemerged arbovirus, a member of the family. It circulates through mosquito vectors mainly of the family and a mammalian host…”
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Defective viral genomes as therapeutic interfering particles against flavivirus infection in mammalian and mosquito hosts
Published in Nature communications (16-04-2021)“…Arthropod-borne viruses pose a major threat to global public health. Thus, innovative strategies for their control and prevention are urgently needed. Here, we…”
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Convalescent Plasma Therapy in Immunocompromised Patients Infected With the BA.1 or BA.2 Omicron SARS‐CoV‐2
Published in Influenza and other respiratory viruses (01-03-2024)“…ABSTRACT The emergence of SARS‐CoV‐2 Omicron variant has led to a complete reconfiguration of the therapeutic landscape, with all monoclonal antibodies having…”
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Cytomegalovirus viremia and risk of disease progression and death in HIV-positive patients starting antiretroviral therapy
Published in AIDS (London) (20-04-2022)Get full text
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[Letter] Cutaneous diphtheria: 3 case-reports to discuss determinants of re-emergence in resource-rich settings
Published in Emerging microbes & infections (18-11-2021)“…Diphtheria is a re-emerging disease in resource-rich settings. We here report three cases of cutaneous diphtheria diagnosed and managed in our infectious…”
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