Search Results - "Levey, Daniel L."

Heat Shock Protein-Mediated Cross-Presentation of Exogenous HIV Antigen on HLA Class I and Class II by SenGupta, Devi, Norris, Philip J, Suscovich, Todd J, Hassan-Zahraee, Mina, Moffett, Howell F, Trocha, Alicja, Draenert, Rika, Goulder, Philip J. R, Binder, Robert J, Levey, Daniel L, Walker, Bruce D, Srivastava, Pramod K, Brander, Christian

“…Strong CD4(+) and CD8(+) T cell responses are considered important immune components for controlling HIV infection, and their priming may be central to an…”
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Cellular Requirements for Tumor-Specific Immunity Elicited by Heat Shock Proteins: Tumor Rejection Antigen gp96 Primes CD8+T Cells in vivo by UDONO, H, LEVEY, D. L, SRIVASTAVA, P. K

“…Purified preparations of 96-kDa heat shock proteins (gp96) have been previously shown to elicit tumor-specific immunity to the tumor from which gp96 is…”
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Safety and immunogenicity of long HSV-2 peptides complexed with rhHsc70 in HSV-2 seropositive persons by Wald, Anna, Koelle, David M, Fife, Kenneth, Warren, Terri, LeClair, Kenneth, Chicz, Roman M, Monks, Stephen, Levey, Daniel L, Musselli, Cristina, Srivastava, Pramod K

“…Highlights ► T-cell immunity is required to contain HSV infection. ► HSV vaccines tested thus far elicited predominantly antibody response. ► A candidate…”
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A heat shock protein based polyvalent vaccine targeting HSV-2: CD4+ and CD8+ cellular immunity and protective efficacy by Mo, Annie, Musselli, Cristina, Chen, Hong, Pappas, John, LeClair, Kenneth, Liu, Aston, Chicz, Roman M, Truneh, Alemseged, Monks, Stephen, Levey, Daniel L, Srivastava, Pramod K

“…Abstract Efforts to develop a subunit vaccine against genital herpes have been hampered by lack of knowledge of the protective antigens of HSV-2, the causative…”
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Vaccination with heat shock protein-peptide complexes: from basic science to clinical applications by Hoos, Axel, Levey, Daniel L

“…There are currently over 150 medical centers worldwide enrolling patients in randomized, controlled Phase III clinical trials testing autologous cancer-derived…”
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High-Affinity Interactions between Peptides and Heat Shock Protein 70 Augment CD8+ T Lymphocyte Immune Responses by Flechtner, Jessica B, Cohane, Kenya Prince, Mehta, Sunil, Slusarewicz, Paul, Leonard, Alexis Kays, Barber, Brian H, Levey, Daniel L, Andjelic, Sofija

“…Exogenously delivered antigenic peptides complexed to heat shock proteins (HSPs) are able to enter the endogenous Ag-processing pathway and prime CD8+ CTL. It…”
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Autologous renal cell cancer vaccines using heat shock protein-peptide complexes by Aalamian, Maryam, Fuchs, Ephraim, Gupta, Renu, Levey, Daniel L.

“…Investigations into the role of heat shock proteins (HSPs) in immune response have progressed well into a third decade, and indications of their use for the…”
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The potential of heat shock protein-peptide complexes as a therapeutic HIV vaccine by Levey, Daniel L, Brander, Christian, Srivastava, Pramod K

“…HIV evades host immune responses through multiple mechanisms including high mutation rate, downregulation of host-cell, HLA class I molecules and depletion of…”
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Abstract 4609: Agenus’ next generation cancer vaccine platforms by Uduman, Mohamed, Khattar, Mithun, Joshi, Bishnu, Tanne, Antoine, Morin, Benjamin, Karapetyan, Armen, Drouin, Elise, Craig, Sandra, Myers, Paisley, Jeffery, Erin, Wilson, Nicholas, Yang, Amy, Engelhard, Victor H., Cobbold, Mark, Hunt, Donald F., Underwood, Dennis, Lin, Shiwen, Findeis, Mark, Raizer, Jeffrey, Goldberg, John, Buell, Jennifer S., Stein, Robert, Levey, Daniel L., Castle, John

“…Most cancer cells carry mutations unique to the patient’s individual tumor and shared biochemical signatures that are not present in healthy cells. Agenus has…”
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A heat shock protein based polyvalent vaccine targeting HSV-2: CD4 super(+ and CD8) super(+) cellular immunity and protective efficacy by Mo, Annie, Musselli, Cristina, Chen, Hong, Pappas, John, LeClair, Kenneth, Liu, Aston, Chicz, Roman M, Truneh, Alemseged, Monks, Stephen, Levey, Daniel L, ivastava, Pramod K

“…Efforts to develop a subunit vaccine against genital herpes have been hampered by lack of knowledge of the protective antigens of HSV-2, the causative agent of…”
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Autologous renal cell cancer vaccines using heat shock protein-peptide complexes : The status of cancer vaccine therapies in urology by AALAMIAN, Maryam, FUCHS, Ephraim, GUPTA, Renu, LEVEY, Daniel L

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High-Affinity Interactions between Peptides and Heat Shock Protein 70 Augment CD8 super(+) T Lymphocyte Immune Responses by Flechtner, Jessica B, Cohane, Kenya Prince, Mehta, Sunil, Slusarewicz, Paul, Leonard, Alexis Kays, Barber, Brian H, Levey, Daniel L, Andjelic, Sofija

“…Exogenously delivered antigenic peptides complexed to heat shock proteins (HSPs) are able to enter the endogenous Ag-processing pathway and prime CD8 super(+)…”
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Alterations in T cells of cancer-bearers: whence specificity? by Levey, Daniel L., Srivastava, Pramod K.

“…T cells of tumor-bearing mice and cancer patients have been reported to have altered signal-transduction machinery. These alterations have been implicated in…”
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