Search Results - "Levesque, M.P."

3349 Hedgehog pathway inhibitors promote adaptive immune responses in basal cell carcinoma by Otsuka, A, Dreier, J, Cheng, P, Nägeli, M, Levesque, M.P, Dummer, R

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Inhibition of oncogenic MAPK signaling in melanoma triggers SOX2-dependent adaptive drug resistance programs by Flueckiger, S, Aloia, A, Frischknecht, L, Tuozzo, A, Croci, D, Shakhova, O, Britschgi, C, Levesque, M.P, Dummer, R, Krek, W

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869P PAK4 as a potential marker for poor response to immunotherapy in melanoma patients by Levesque, M.P., Martinez, J., Kuo, J., Nunns, H., Treiber, T., Kakalacheva-Beeler, K., Vowinckel, J., Juncker-Jensen, A.

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1339P - Integrative RNAseq and target panel sequencing reveals common and distinct innate and adaptive resistance mechanisms to BRAF inhibitors by Cheng, P.F., Freiberger, S.N., Panetti, C., Irmisch, A., Dummer, R., Levesque, M.P.

“…Targeted therapy in melanoma has been a great success in extending progression free survival and overall survival for melanoma patients. These include BRAF…”
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Integrative RNAseq and target panel sequencing reveals common and distinct innate and adaptive resistance mechanisms to BRAF inhibitors by Cheng, P.F., Freiberger, S.N., Panetti, C., Irmisch, A., Dummer, R., Levesque, M.P.

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1169P Tumour transcriptional and spatial protein profiling in Mexican patients reveals that acral lentiginous melanoma is characterized by an immunosuppressive microenvironment by Vázquez-Cruz, M.E., Molina-Aguilar, C., Basurto-Lozada, P., Martinez Said, H., Álvarez Cano, A., Garcia-Ortega, D.Y., Tavares-de la Paz, L.A., Hinojosa-Ugarte, D., Hidalgo Miranda, A., Abrao Possik, P., Ferreira, I., Martinez, J.M., Levesque, M.P., Adams, D., Robles-Espinoza, C.D.

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PO-1571: Radiomics for prediction of metastatic melanoma patient survival after immunotherapy by Gabrys, H., Basler, L., Hogan, S., Pavic, M., Bogowicz, M., Vuong, D., Tanadini-Lang, S., Förster, R., Huellner, M., Dummer, R., Guckenberger, M., Levesque, M.P.

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243P Skin biopsies for pharmacodynamic studies of tebentafusp: A novel bispecific molecule against the melanocytic antigen gp100 by Stäger, R., Tastanova, A., Ramelyte, E., Levesque, M.P., Dummer, R., Meier-Schiesser, B.

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Sox2 is dispensable for primary melanoma and metastasis formation by Schaefer, S M, Segalada, C, Cheng, P F, Bonalli, M, Parfejevs, V, Levesque, M P, Dummer, R, Nicolis, S K, Sommer, L

“…Tumor initiation and metastasis formation in many cancers have been associated with emergence of a gene expression program normally active in embryonic or…”
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Bimodular Auxin Response Controls Organogenesis in Arabidopsis by De Smet, Ive, Lau, Steffen, Voß, Ute, Vanneste, Steffen, Benjamins, René, Rademacher, Eike H., Schlereth, Alexandra, De Rybel, Bert, Vassileva, Valya, Grunewald, Wim, Naudts, Mirande, Levesque, Mitchell P., Ehrismann, Jasmin S., Inzé, Dirk, Luschnig, Christian, Benfey, Philip N., Weijers, Dolf, Van Montagu, Marc C. E., Bennett, Malcolm J., Jürgens, Gerd, Beeckman, Tom

“…Like animals, the mature plant body develops via successive sets of instructions that determine cell fate, patterning, and organogenesis. In the coordination…”
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Increased tumour cell PD‐L1 expression, macrophage and dendritic cell infiltration characterise the tumour microenvironment of ulcerated primary melanomas by Koelblinger, P., Emberger, M., Drach, M., Cheng, P.F., Lang, R., Levesque, M.P., Bauer, J.W., Dummer, R.

“…Background Primary melanoma ulceration is an unfavourable prognostic factor included in current staging systems. Yet, the immunological and molecular…”
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Naevus spilus-type congenital melanocytic naevus associated with a novel NRAS codon 61 mutation by Krengel, S., Widmer, D.S., Kerl, K., Levesque, M.P., Schiestl, C., Weibel, L.

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887 - Inhibition of oncogenic MAPK signaling in melanoma triggers SOX2-dependent adaptive drug resistance programs by Flueckiger, S., Aloia, A., Frischknecht, L., Tuozzo, A., Croci, D., Shakhova, O., Britschgi, C., Levesque, M.P., Dummer, R., Krek, W.

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Systemic treatment influences on immune accessibility of melanoma: A retrospective histopathological investigation by Krähenbühl, L., Goldinger, S.M., Kerl, K., Kempf, W., Chevolet, I., Brochez, L., Cheng, P., Mangana, J., Levesque, M.P., Dummer, R.

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Basal cell carcinomas in a tertiary referral centre: a systematic analysis by Dreier, J., Cheng, P.F., Bogdan Alleman, I., Gugger, A., Hafner, J., Tschopp, A., Goldinger, S.M., Levesque, M.P., Dummer, R.

“…Summary Background Basal cell carcinoma (BCC) is the most frequent skin cancer with increasing incidence and generally high cure rates. BCC can be quite…”
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An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel by Thurneysen, S., Cheng, P.F., Nagel, H.W., Kunz, M., Jaberg-Bentele, N., Nägeli, M., Ziegler, M., Guenova, E., Goldinger, S.M., Mangana, J., Levesque, M.P., Dummer, R.

“…Summary Background There is a medical need for new drugs in patients with BRAF wild‐type metastatic melanoma. Pazopanib is a multitarget tyrosine kinase…”
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19P Effects of CTLA-4 single nucleotide polymorphisms (SNPs) on toxicity of ipilimumab-containing regimens in patients with advanced stage melanoma by Joode, K.D., Rojas Mora, A., Van Schaik, R., Zippelius, A., Van der Veldt, A.A.M., Gerard, C.L., Läubli, H., Michielin, O.A., von Moos, R.A.F., Joerger, M., Levesque, M.P., Aeppli, S., Mangana, J., Mangas, C., Meyer, S., Leoni-Parvex, S., Mathijssen, R.H., Metaxas, Y.

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Integrated transcriptomics reveals cellular and molecular interactions in pruritic cutaneous T-cell lymphoma by Roggo, A., Ghosh, A., Turko, P., Nägeli, M., Ramelyte, E., Levesque, M.P., Tastanova, A., Dummer, R.

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A-113 - Integrated transcriptomics reveals cellular and molecular interactions in pruritic cutaneous T-cell lymphoma by Roggo, A., Ghosh, A., Turko, P., Nägeli, M., Ramelyte, E., Levesque, M.P., Tastanova, A., Dummer, R.

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Real-world outcomes for advanced melanoma in the adjuvant and unresectable setting: Single-center registry analysis by Staeger, R., Martínez-Gómez, J.M., Ramelyte, E., Kraehenbuehl, L., Levesque, M.P., Dummer, R., Mangana, J.

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