Search Results - "Levental, I."

Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape by Lorent, J. H., Levental, K. R., Ganesan, L., Rivera-Longsworth, G., Sezgin, E., Doktorova, M., Lyman, E., Levental, I.

“…A fundamental feature of cellular plasma membranes (PMs) is an asymmetric lipid distribution between the bilayer leaflets. However, neither the detailed,…”
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Isolation of giant plasma membrane vesicles for evaluation of plasma membrane structure and protein partitioning by Levental, K R, Levental, I

“…Although investigation into the structure of eukaryotic cell membranes has been an intense focus of cell biology for the past two decades, definitive insights…”
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Author Correction: Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape by Lorent, JH, Levental, KR, Ganesan, L, Rivera-Longsworth, G, Sezgin, E, Doktorova, M, Lyman, E, Levental, I

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Author Correction: Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape by Lorent, J. H., Levental, K. R., Ganesan, L., Rivera-Longsworth, G., Sezgin, E., Doktorova, M., Lyman, E., Levental, I.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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A simple indentation device for measuring micrometer-scale tissue stiffness by Levental, I, Levental, K R, Klein, E A, Assoian, R, Miller, R T, Wells, R G, Janmey, P A

“…Mechanical properties of cells and extracellular matrices are critical determinants of function in contexts including oncogenic transformation, neuronal…”
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Electrostatic Contribution to the Surface Pressure of Charged Monolayers Containing Polyphosphoinositides by Levental, I., Janmey, P.A., Cēbers, A.

“…Structural and functional studies of lateral heterogeneity in biological membranes have underlined the importance of membrane organization in biological…”
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HIV infection changes glomerular podocyte cytoskeletal composition and results in distinct cellular mechanical properties by Tandon, R, Levental, I, Huang, C, Byfield, F J, Ziembicki, J, Schelling, J R, Bruggeman, L A, Sedor, J R, Janmey, P A, Miller, R T

“…In addition to forming the selective filtration barrier for the renal glomerulus, podocytes maintain glomerular capillary architecture by opposing distending…”
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The mystery of membrane organization: composition, regulation and roles of lipid rafts by Sezgin, Erdinc, Levental, Ilya, Mayor, Satyajit, Eggeling, Christian

“…Key Points Cellular membranes are laterally heterogeneous and consist of transient and dynamic domains with varying properties, which prominently include…”
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Membranes in focus by Sezgin, Erdinc, Levental, Ilya

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Regulation of lipid saturation without sensing membrane fluidity by Ballweg, Stephanie, Sezgin, Erdinc, Doktorova, Milka, Covino, Roberto, Reinhard, John, Wunnicke, Dorith, Hänelt, Inga, Levental, Ilya, Hummer, Gerhard, Ernst, Robert

“…Cells maintain membrane fluidity by regulating lipid saturation, but the molecular mechanisms of this homeoviscous adaptation remain poorly understood. We have…”
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Elucidating membrane structure and protein behavior using giant plasma membrane vesicles by Sezgin, Erdinc, Kaiser, Hermann-Josef, Baumgart, Tobias, Schwille, Petra, Simons, Kai, Levental, Ilya

“…The observation of phase separation in intact plasma membranes isolated from live cells is a breakthrough for research into eukaryotic membrane lateral…”
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Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes by Sezgin, Erdinc, Levental, Ilya, Grzybek, Michal, Schwarzmann, Günter, Mueller, Veronika, Honigmann, Alf, Belov, Vladimir N., Eggeling, Christian, Coskun, Ünal, Simons, Kai, Schwille, Petra

“…Several simplified membrane models featuring coexisting liquid disordered (Ld) and ordered (Lo) lipid phases have been developed to mimic the heterogeneous…”
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Fibroblast Adaptation and Stiffness Matching to Soft Elastic Substrates by Solon, Jérôme, Levental, Ilya, Sengupta, Kheya, Georges, Penelope C., Janmey, Paul A.

“…Many cell types alter their morphology and gene expression profile when grown on chemically equivalent surfaces with different rigidities. One expectation of…”
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Adaptive lipid packing and bioactivity in membrane domains by Sezgin, Erdinc, Gutmann, Theresia, Buhl, Tomasz, Dirkx, Ron, Grzybek, Michal, Coskun, Ünal, Solimena, Michele, Simons, Kai, Levental, Ilya, Schwille, Petra

“…Lateral compositional and physicochemical heterogeneity is a ubiquitous feature of cellular membranes on various length scales, from molecular assemblies to…”
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Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis by Matias, Maria I., Yong, Carmen S., Foroushani, Amir, Goldsmith, Chloe, Mongellaz, Cédric, Sezgin, Erdinc, Levental, Kandice R., Talebi, Ali, Perrault, Julie, Rivière, Anais, Dehairs, Jonas, Delos, Océane, Bertand-Michel, Justine, Portais, Jean-Charles, Wong, Madeline, Marie, Julien C., Kelekar, Ameeta, Kinet, Sandrina, Zimmermann, Valérie S., Levental, Ilya, Yvan-Charvet, Laurent, Swinnen, Johannes V., Muljo, Stefan A., Hernandez-Vargas, Hector, Tardito, Saverio, Taylor, Naomi, Dardalhon, Valérie

“…Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic signaling pathways and intracellular metabolites. Here we show…”
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Author Correction: Hitchhiking into the cell by Kell, Douglas B.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Bile Acids Modulate Signaling by Functional Perturbation of Plasma Membrane Domains by Zhou, Yong, Maxwell, Kelsey N., Sezgin, Erdinc, Lu, Maryia, Liang, Hong, Hancock, John F., Dial, Elizabeth J., Lichtenberger, Lenard M., Levental, Ilya

“…Eukaryotic cell membranes are organized into functional lipid and protein domains, the most widely studied being membrane rafts. Although rafts have been…”
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Immunotherapy: SIGNALING DOMAINS, 41BB AND CD28, MEDIATE DISTINCT MOLECULAR DYNAMICS AT THE IMMUNE SYNAPSE THAT INFLUENCE CAR T CELL KILLING BEHAVIOR by Gad, A.Z., Morris, J.S., Godret-Miertschin, L., Montalvo, M.J., Fousek, K., Saeedi, A., Levental, K., Mamonkin, M., Carisey, A., Joseph, S., Hegde, M., Varadarajan, N., Levental, I., Mukherjee, M., Ahmed, N.

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334 The desmosome is a mesoscale lipid raft-like membrane domain by Caldara, A.L., Lewis, J.D., Zimmer, S.E., Seybold, A., Strong, N.L., Stahley, S.N., Frangakis, A.S., Levental, I., Wahl, J.K., Mattheyses, A.L., Sasaki, T., Nakabayashi, K., Hata, K., Matsubara, Y., Ishida-Yamamoto, A., Amagai, M., Kubo, A., Kowalczyk, A.P.

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Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains by Beck-García, Katharina, Beck-García, Esmeralda, Bohler, Sheila, Zorzin, Carina, Sezgin, Erdinc, Levental, Ilya, Alarcón, Balbino, Schamel, Wolfgang W.A.

“…In the last decade an increasing number of plasma membrane (PM) proteins have been shown to be non-randomly distributed but instead forming submicron-sized…”
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