Search Results - "Levenston, M E"

Fact versus artifact: avoiding erroneous estimates of sulfated glycosaminoglycan content using the dimethylmethylene blue colorimetric assay for tissue-engineered constructs by Zheng, C H, Levenston, M E

“…The 1,9-dimethylmethylene blue (DMMB) assay is widely used to quantify sulfated glycosaminoglycan (sGAG) contents of engineered tissues, culture media, tissue…”
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Discrimination of meniscal cell phenotypes using gene expression profiles by Son, M, Levenston, M E

“…The lack of quantitative and objective metrics to assess cartilage and meniscus cell phenotypes contributes to the challenges in fibrocartilage tissue…”
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Fibronectin- and collagen-mimetic ligands regulate bone marrow stromal cell chondrogenesis in three-dimensional hydrogels by Connelly, J T, Petrie, T A, García, A J, Levenston, M E

“…Modification of tissue engineering scaffolds with bioactive molecules is a potential strategy for modulating cell behavior and guiding tissue regeneration…”
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Ion-channel regulation of chondrocyte matrix synthesis in 3D culture under static and dynamic compression by Mouw, J K, Imler, S M, Levenston, M E

“…Inhibition of various ion channels alters chondrocyte mechanotransduction in monolayer, but the mechanisms involved in chondrocyte mechanotransduction in…”
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Chondrocyte phenotypes on different extracellular matrix monolayers by Brodkin, K.R., Garcı́a, A.J., Levenston, M.E.

“…Chondrocytes undergo a process of dedifferentiation in monolayer culture that is characterized by a transition to a fibroblast-like phenotype. This behavioral…”
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Non-ionic CT contrast solutions rapidly alter bovine cartilage and meniscus mechanics by Baylon, E.G., Crowder, H.A., Gold, G.E., Levenston, M.E.

“…To evaluate effects of a common CT contrast agent (iohexol) on the mechanical behaviors of cartilage and meniscus. Indentation responses of juvenile bovine…”
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Meniscus is more susceptible than cartilage to catabolic and anti-anabolic effects of adipokines by Nishimuta, J.F, Levenston, M.E

“…Summary Objective This study compared the effects on cartilage and meniscus matrix catabolism and biosynthesis of several adipokines implicated in…”
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Rapid and durable photochemical bonding of cartilage using the porphyrin photosensitizer verteporfin by Arvayo, A.L., Imbrie-Moore, A., Levenston, M.E.

“…To evaluate the effectiveness of verteporfin as a photosensitizer to photochemically bond articular cartilage tissues and determine bond durability in vitro…”
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Meniscus and cartilage exhibit distinct intra-tissue strain distributions under unconfined compression by Lai, J.H, Levenston, M.E

“…Summary Objective To examine the functional behavior of the surface layer of the meniscus by investigating depth-varying compressive strains during unconfined…”
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Regional variation in T1ρ and T2 times in osteoarthritic human menisci: correlation with mechanical properties and matrix composition by Son, M, Goodman, S.B, Chen, W, Hargreaves, B.A, Gold, G.E, Levenston, M.E

“…Summary Objective Changes in T1ρ and T2 magnetic resonance relaxation times have been associated with articular cartilage degeneration, but similar…”
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Response of cartilage and meniscus tissue explants to in vitro compressive overload by Nishimuta, J.F, Levenston, M.E

“…Summary Objective To examine the relative susceptibility of cartilage and meniscus tissues to mechanical injury by applying a single, controlled overload and…”
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Central and peripheral region tibial plateau chondrocytes respond differently to in vitro dynamic compression by Bevill, S.L, Briant, P.L, Levenston, M.E, Andriacchi, T.P

“…Summary Objective The objective of this study was to test the hypotheses that chondrocytes from distinct regions of the porcine tibial plateau: (1) display…”
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Bite-force estimation for Tyrannosaurus rex from tooth-marked bones by Erickson, Gregory M, Kirk, Samuel D. Van, Su, Jinntung, Levenston, Marc E, Caler, William E, Carter, Dennis R

“…Paleontologists have turned to the study of dental morphology to address the question of whether tyrannosaurs occupied predatory or scavenging niches. So far,…”
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Articular chondrocytes derived from distinct tissue zones differentially respond to in vitro oscillatory tensile loading by Vanderploeg, E.J., Ph.D, Wilson, C.G., Ph.D, Levenston, M.E., Ph.D

“…Summary Objective The cell morphology, gene expression, and matrix synthesis of articular chondrocytes are known to vary with depth from the tissue surface…”
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Variationally derived 3-field finite element formulations for quasistatic poroelastic analysis of hydrated biological tissues by Levenston, M.E., Frank, E.H., Grodzinsky, A.J.

“…Hydrated biological tissues are often modeled mechanically as poroelastic media with intrinsically incompressible solid and fluid constituents. Unlike many…”
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Characterization of proteoglycan production and processing by chondrocytes and BMSCs in tissue engineered constructs by Connelly, J.T., Ph.D, Wilson, C.G., Ph.D, Levenston, M.E., Ph.D

“…Summary Objective The goal of this study was to characterize the proteoglycan (PG) production and processing by bone marrow stromal cells (BMSCs) within a…”
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Composition-function relationships during IL-1-induced cartilage degradation and recovery by Palmer, A.W, Wilson, C.G, Baum, E.J, Levenston, M.E

“…Summary Objective To examine the relationships between biochemical composition and mechanical properties of articular cartilage explants during interleukin-1…”
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Photochemical approaches for bonding of cartilage tissues by Sitterle, V.B, Nishimuta, J.F, Levenston, M.E

“…Summary Objective The objective of this study was to evaluate photochemical bonding as an approach for adhering live cartilage tissues across a repair…”
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CARTILAGE TISSUE REMODELING IN RESPONSE TO MECHANICAL FORCES by Grodzinsky, Alan J, Levenston, Marc E, Jin, Moonsoo, Frank, Eliot H

“…Recent studies suggest that there are multiple regulatory pathways by which chondrocytes in articular cartilage sense and respond to mechanical stimuli,…”
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Variations in matrix composition and GAG fine structure among scaffolds for cartilage tissue engineering by Mouw, J.K., Case, N.D., Guldberg, R.E., Plaas, A.H.K., Levenston, M.E.

“…To compare matrix composition and glycosaminoglycan (GAG) fine structure among five scaffolds commonly used for in vitro chondrocyte culture and cartilage…”
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