Search Results - "Levengood, Jeffrey D."

Differential Binding between PatS C-Terminal Peptide Fragments and HetR from Anabaena sp. PCC 7120 by Feldmann, Erik A, Ni, Shuisong, Sahu, Indra D, Mishler, Clay H, Levengood, Jeffrey D, Kushnir, Yegor, McCarrick, Robert M, Lorigan, Gary A, Tolbert, Blanton S, Callahan, Sean M, Kennedy, Michael A

“…Heterocyst differentiation in the filamentous cyanobacterium Anabaena sp. strain PCC 7120 occurs at regular intervals under nitrogen starvation and is…”
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Idiosyncrasies of hnRNP A1-RNA recognition: Can binding mode influence function by Levengood, Jeffrey D., Tolbert, Blanton S.

“…The heterogeneous nuclear ribonucleoproteins (hnRNPs) are a diverse family of RNA binding proteins that function in most stages of RNA metabolism. The…”
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Thermodynamic stability of hnRNP A1 low complexity domain revealed by high‐pressure NMR by Levengood, Jeffrey D., Peterson, Jake, Tolbert, Blanton S., Roche, Julien

“…We have investigated the pressure‐ and temperature‐induced conformational changes associated with the low complexity domain of hnRNP A1, an RNA‐binding protein…”
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Nonorthologous Replacement of Lysyl-tRNA Synthetase Prevents Addition of Lysine Analogues to the Genetic Code by Jester, Brian C., Levengood, Jeffrey D., Roy, Hervé, Ibba, Michael, Devine, Kevin M.

“…Insertion of lysine during protein synthesis depends on the enzyme lysyl-tRNA synthetase (LysRS), which exists in two unrelated forms, LysRS1 and LysRS2…”
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The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein by Morgan, Christopher E, Meagher, Jennifer L, Levengood, Jeffrey D, Delproposto, James, Rollins, Carrie, Stuckey, Jeanne A, Tolbert, Blanton S

“…The heterogeneous nuclear ribonucleoprotein (hnRNP) A1 protein is a multifunctional RNA binding protein implicated in a wide range of biological functions…”
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High-affinity interaction of hnRNP A1 with conserved RNA structural elements is required for translation and replication of enterovirus 71 by Levengood, Jeffrey D., Tolbert, Michele, Li, Mei-Ling, Tolbert, Blanton S.

“…Human Enterovirus 71 (EV71) is an emerging pathogen of infectious disease and a serious threat to public health. Currently, there are no antivirals or vaccines…”
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Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions by Levengood, Jeffrey D, Potoyan, Davit, Penumutchu, Srinivasa, Kumar, Abhishek, Zhou, Qianzi, Wang, Yiqing, Hansen, Alexandar L, Kutluay, Sebla, Roche, Julien, Tolbert, Blanton S

“…The functional properties of RNA binding proteins (RBPs) require allosteric regulation through interdomain communication. Despite the importance of allostery…”
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Thermodynamic and Phylogenetic Insights into hnRNP A1 Recognition of the HIV‑1 Exon Splicing Silencer 3 Element by Rollins, Carrie, Levengood, Jeffrey D, Rife, Brittany D, Salemi, Marco, Tolbert, Blanton S

“…Complete expression of the HIV-1 genome requires balanced usage of suboptimal splice sites. The 3′ acceptor site A7 (ssA7) is negatively regulated in part by…”
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Solution Structure of the HIV-1 Exon Splicing Silencer 3 by Levengood, Jeffrey D., Rollins, Carrie, Mishler, Clay H.J., Johnson, Charles A., Miner, Grace, Rajan, Prashant, Znosko, Brent M., Tolbert, Blanton S.

“…Alternative splicing of the human immunodeficiency virus type 1 (HIV-1) genomic RNA is necessary to produce the complete viral protein complement, and…”
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Anticodon Recognition and Discrimination by the α-Helix Cage Domain of Class I Lysyl-tRNA Synthetase by Levengood, Jeffrey D, Roy, Hervé, Ishitani, Ryuichiro, Söll, Dieter, Nureki, Osamu, Ibba, Michael

“…Aminoacyl-tRNA synthetases are normally found in one of two mutually exclusive structural classes, the only known exception being lysyl-tRNA synthetase which…”
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Thermodynamic Stability of hnRNP A1 Low Complexity Domain Revealed by High-Pressure NMR by Levengood, Jeffrey D., Peterson, Jake, Tolbert, Blanton S., Roche, Julien

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The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein by Morgan, Christopher E., Meagher, Jennifer L., Levengood, Jeffrey D., Delproposto, James, Rollins, Carrie, Stuckey, Jeanne A., Tolbert, Blanton S.

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