Search Results - "Levacher, Béatrice"

Bone Marrow Mesenchymal Stem Cells Suppress Lymphocyte Proliferation In Vitro but Fail to Prevent Graft-versus-Host Disease in Mice by Sudres, Muriel, Norol, Francoise, Trenado, Aurelie, Gregoire, Sylvie, Charlotte, Frederic, Levacher, Beatrice, Lataillade, Jean-Jacques, Bourin, Philippe, Holy, Xavier, Vernant, Jean-Paul, Klatzmann, David, Cohen, Jose L

“…Several reports have suggested that mesenchymal stem cells (MSCs) could exert a potent immunosuppressive effect in vitro, and thus may have a therapeutic…”
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Induction of antigen-specific tolerance by intrathymic injection of lentiviral vectors by Marodon, Gilles, Fisson, Sylvain, Levacher, Béatrice, Fabre, Monique, Salomon, Benoît L., Klatzmann, David

“…Immune tolerance to self-antigens is established during lymphocyte differentiation in the thymus, but a simple means to induce antigen-specific tolerance in…”
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Noradrenergic neuronal development is impaired by mutation of the proneural HASH-1 gene in congenital central hypoventilation syndrome (Ondine's curse) by de Pontual, Loïc, Népote, Virginie, Attié-Bitach, Tania, Al Halabiah, Hassan, Trang, Ha, Elghouzzi, Vincent, Levacher, Béatrice, Benihoud, Karim, Augé, Joëlle, Faure, Christophe, Laudier, Béatrice, Vekemans, Michel, Munnich, Arnold, Perricaudet, Michel, Guillemot, François, Gaultier, Claude, Lyonnet, Stanislas, Simonneau, Michel, Amiel, Jeanne

“…Congenital central hypoventilation syndrome (CCHS, Ondine's curse) is a rare disorder of the chemical control of breathing. It is frequently associated with a…”
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Low-Dose IL-2 Induces Regulatory T Cell-Mediated Control of Experimental Food Allergy by Bonnet, Benjamin, Vigneron, James, Levacher, Béatrice, Vazquez, Thomas, Pitoiset, Fabien, Brimaud, Faustine, Churlaud, Guillaume, Klatzmann, David, Bellier, Bertrand

“…Regulatory T cells (Tregs) are pivotal for maintenance of immune self-tolerance and also regulate immune responses to exogenous Ags, including allergens. Both…”
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Particulate antigens administrated by intranasal and intravaginal routes in a prime-boost strategy improve HIV-specific TFH generation, high-quality antibodies and long-lasting mucosal immunity by Vazquez, Thomas, Torrieri-Damard, Léa, Pitoiset, Fabien, Levacher, Béatrice, Vigneron, James, Mayr, Luzia, Brimaud, Faustine, Bonnet, Benjamin, Moog, Christiane, Klatzmann, David, Bellier, Bertrand

“…[Display omitted] Mucosal surfaces serve as the primary entry points for pathogens such as SARS- CoV-2 coronavirus or HIV in the human body. Mucosal…”
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TGF- β and VEGF cooperatively control the immunotolerant tumor environment and the efficacy of cancer immunotherapies by Courau, Tristan, Nehar-Belaid, Djamel, Florez, Laura, Levacher, Béatrice, Vazquez, Thomas, Brimaud, Faustine, Bellier, Bertrand, Klatzmann, David

“…Tregs imprint an early immunotolerant tumor environment that prevents effective antitumor immune responses. Using transcriptomics of tumor tissues, we…”
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Retrovirus-Based Virus-Like Particle Immunogenicity and Its Modulation by Toll-Like Receptor Activation by Pitoiset, Fabien, Vazquez, Thomas, Levacher, Beatrice, Nehar-Belaid, Djamel, Dérian, Nicolas, Vigneron, James, Klatzmann, David, Bellier, Bertrand

“…Retrovirus-derived virus-like particles (VLPs) are particularly interesting vaccine platforms, as they trigger efficient humoral and cellular immune responses…”
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Treatment of Uveitis by In Situ Administration of Ex Vivo-Activated Polyclonal Regulatory T Cells by Grégoire, Sylvie, Terrada, Céline, Martin, Gaelle H, Fourcade, Gwladys, Baeyens, Audrey, Marodon, Gilles, Fisson, Sylvain, Billiard, Fabienne, Lucas, Bruno, Tadayoni, Ramin, Béhar-Cohen, Francine, Levacher, Béatrice, Galy, Anne, LeHoang, Phuc, Klatzmann, David, Bodaghi, Bahram, Salomon, Benoît L

“…CD4(+)CD25(+)Foxp3(+) regulatory T (Treg) cell therapy is a promising approach for the treatment of autoimmune diseases. To be effective, Treg cells should be…”
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Murine peripherin gene sequences direct Cre recombinase expression to peripheral neurons in transgenic mice by Zhou, Li, Népote, Virginie, Rowley, Daniel L, Levacher, Béatrice, Zvara, Agnes, Santha, Miklos, Mi, Qing-Sheng, Simonneau, Michel, Donovan, David M

“…Spatially and temporally regulated somatic mutations can be achieved by using the Cre/loxP recombination system of bacteriophage P1. To develop a cell…”
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Recombinant retrovirus-derived virus-like particle-based vaccines induce hepatitis C virus-specific cellular and neutralizing immune responses in mice by Huret, Christophe, Desjardins, Delphine, Miyalou, Mathilde, Levacher, Béatrice, Amadoudji Zin, Martin, Bonduelle, Olivia, Combadière, Béhazine, Dalba, Charlotte, Klatzmann, David, Bellier, Bertrand

“…Highlights ► We developed retrovirus-based VLPs as HCV-specific vaccine platform. ► Both ex vivo produced VLPs or plasmid DNA encoding VLPs can be used as…”
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Targeting both viral and host determinants of human immunodeficiency virus entry, using a new lentiviral vector coexpressing the T20 fusion inhibitor and a selective CCL5 intrakine by Petit, Nicolas, Dorgham, Karim, Levacher, Béatrice, Burlion, Aude, Gorochov, Guy, Marodon, Gilles

“…Numerous strategies targeting early and late steps of the HIV life cycle have been proposed for gene therapy. However, targeting viral and host determinants of…”
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Glial cell line derived neurotrophic factor is expressed by epithelia of human renal dysplasia by El-Ghoneimi, Alaa, Berrebi, Dominique, Levacher, Beatrice, Nepote, Virginie, Infante, MurielL, Paris, Regine, Simonneau, Michel, Aigrain, Yves, Peuchmaur, Michel

“…Differentiation of the metanephros is abnormal in cases of renal dysplasia, resulting in abnormal kidney organization. In vitro and in vivo studies indicate…”
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MASH-1/RET pathway involvement in development of brain stem control of respiratory frequency in newborn mice by DAUGER, STEPHANE, GUIMIOT, FABIEN, RENOLLEAU, SYLVAIN, LEVACHER, BEATRICE, BODA, BERNADETTE, MAS, CHRISTOPHE, NEPOTE, VIRGINIE, SIMONNEAU, MICHEL, GAULTIER, CLAUDE, GALLEGO, JORGE

“…1 Laboratoire de Neurologie et Physiologie du Développement, Institut National de la Santé et de la Recherche Médicale E9935 2 Service de Pédiatrie…”
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Survival motor neuron SMN1 and SMN2 gene promoters: identical sequences and differential expression in neurons and non-neuronal cells by BODA, Bernadett, MAS, Christophe, GIUDICELLI, Catherine, NEPOTE, Virginie, GUIMIOT, Fabien, LEVACHER, Béatrice, ZVARA, Agnes, SANTHA, Miklos, LEGALL, Isabelle, SIMONNEAU, Michel

“…Spinal muscular atrophy (SMA) is a recessive disorder involving the loss of motor neurons from the spinal cord. Homozygous absence of the survival of motor…”
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Developmental regulation of replication fork pausing in Xenopus laevis ribosomal RNA genes by Maric, Chrystelle, Levacher, Béatrice, Hyrien, Olivier

“…In early Xenopus embryos, replication forks move along the rRNA genes (rDNA) at a uniform rate and terminate at multiple, apparently random sites. In contrast,…”
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Impaired ventilatory responses to hypoxia in mice deficient in endothelin-converting-enzyme-1 by RENOLLEAU, Sylvain, DAUGER, Stéphane, VARDON, Guy, LEVACHER, Béatrice, SIMONNEAU, Michel, YANAGISAWA, Masashi, GAULTIER, Claude, GALLEGO, Jorge

“…Endothelin-converting-enzyme (ECE-1) catalyzes the proteolytic activation of big endothelin-1 to mature endothelin-1. Most homozygous ECE-1-/- embryos die in…”
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Ventilatory responses to hypercapnia and hypoxia in heterozygous c-ret newborn mice by Aizenfisz, Sophie, Dauger, Stéphane, Durand, Estelle, Vardon, Guy, Levacher, Béatrice, Simonneau, Michel, Pachnis, Vassilis, Gaultier, Claude, Gallego, Jorge

“…The c-ret proto-oncogene encodes a tyrosine-kinase receptor involved in survival and differentiation of neural crest cell lineages. Previous studies have shown…”
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Molecular cloning and expression pattern of the Fkbp25 gene during cerebral cortical neurogenesis by Mas, Christophe, Guimiot-Maloum, Ismahane, Guimiot, Fabien, Khelfaoui, Malik, Nepote, Virginie, Bourgeois, Francine, Boda, Bernadett, Levacher, Béatrice, Galat, Andrzej, Moalic, Jean-Marie, Simonneau, Michel

“…Neocortical neurons are generated predominantly from the cells that proliferate in the ventricular zone of the telencephalon. In order to understand the nature…”
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Cloning and Expression Analysis of a Novel Gene, RP42, Mapping to an Autism Susceptibility Locus on 6q16 by Mas, Christophe, Bourgeois, Francine, Bulfone, Alessandro, Levacher, Béatrice, Mugnier, Claude, Simonneau, Michel

“…We isolated a novel mouse gene, RP42, in a systematic search for genes expressed in proliferating neuroblasts whose human orthologs map to suspectibility loci…”
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