Search Results - "Leung, W.Y."

SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease by Perera, Ranawaka A P M, Tso, Eugene, Tsang, Owen T Y, Tsang, Dominic N C, Fung, Kitty, Leung, Yonna W Y, Chin, Alex W H, Chu, Daniel K W, Cheng, Samuel M S, Poon, Leo L M, Chuang, Vivien W M, Peiris, Malik

“…We investigated 68 respiratory specimens from 35 coronavirus disease patients in Hong Kong, of whom 32 had mild disease. We found that severe acute respiratory…”
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Equilibria of bilateral taxi–customer searching and meeting on networks by Yang, Hai, Leung, Cowina W.Y., Wong, S.C., Bell, Michael G.H.

“…This paper proposes an equilibrium model to characterize the bilateral searching and meeting between customers and taxis on road networks. A taxi driver…”
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Hepatitis B Virus Reactivation in Lymphoma Patients With Prior Resolved Hepatitis B Undergoing Anticancer Therapy With or Without Rituximab by YEO, Winnie, CHAN, Tung C, CHAN, Paul K. S, LEUNG, Nancy W. Y, LAM, Wai Y, MO, Frankie K. F, MIU TING CHU, CHAN, Henry L. Y, HUI, Edwin P, LEI, Kenny I. K, MOK, Tony S. K

“…Reactivation of hepatitis B virus (HBV) infection is a well-recognized complication in cancer patients with chronic HBV (hepatitis B surface antigen [HBsAg]…”
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A One-Year Trial of Lamivudine for Chronic Hepatitis B by Lai, Ching-Lung, Chien, Rong-Nan, Leung, Nancy W.Y, Chang, Ting-Tsung, Guan, Richard, Tai, Dar-In, Ng, Keng-Yeen, Wu, Pui-Chee, Dent, Julie C, Barber, Judy, Stephenson, Sally L, Gray, D. Fraser

“…Throughout the world, over 300 million people have chronic infection with hepatitis B virus (HBV), and more than 75 percent of those affected are of Asian…”
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Sulfonation, an underexploited area: from skeletal development to infectious diseases and cancer by Leung, Ada W. Y., Backstrom, Ian, Bally, Marcel B

“…Sulfonation is one of the most abundant cellular reactions modifying a wide range of xenobiotics as well as endogenous molecules which regulate important…”
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Liposomal Formulations to Modulate the Tumour Microenvironment and Antitumour Immune Response by Gilabert-Oriol, Roger, Ryan, Gemma M, Leung, Ada W Y, Firmino, Natalie S, Bennewith, Kevin L, Bally, Marcel B

“…Tumours are complex systems of genetically diverse malignant cells that proliferate in the presence of a heterogeneous microenvironment consisting of host…”
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Decay-Accelerating Factor Suppresses Complement C3 Activation and Retards Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice by Leung, Viola W.Y, Yun, Sheng, Botto, Marina, Mason, Justin C, Malik, Talat H, Song, Wenchao, Paixao-Cavalcante, Danielle, Pickering, Matthew C, Boyle, Joseph J, Haskard, Dorian O

“…Decay-accelerating factor (DAF; CD55) is a membrane protein that regulates complement pathway activity at the level of C3. To test the hypothesis that DAF…”
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Brief Report: Accelerated Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice Lacking the Membrane-Bound Complement Regulator CD59 by Yun, Sheng, Leung, Viola W.Y, Botto, Marina, Boyle, Joseph J, Haskard, Dorian O

“…OBJECTIVE—Whereas studies in humans and animal models have suggested a role for complement activation in atherosclerosis, there has been little analysis of the…”
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H-type recto-urethral fistula presenting with recurrent epididymo-orchitis by Cheung, Stephanie L.H., Hung, Judy W.S., Chung, Kenneth L.Y., Leung, Michael W.Y.

“…Anorectal malformation (ARM) is a congenital malformation that has an incidence of 1 in 5000. Krickenbeck classification separate different types of ARM…”
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What Drives Innovation: The Canadian Touch on Liposomal Therapeutics by Leung, Ada W Y, Amador, Carolyn, Wang, Lin Chuan, Mody, Urmi V, Bally, Marcel B

“…Liposomes are considered one of the most successful drug delivery systems (DDS) given their established utility and success in the clinic. In the past 40⁻50…”
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A simple passive equilibration method for loading carboplatin into pre-formed liposomes incubated with ethanol as a temperature dependent permeability enhancer by Wehbe, Moe, Malhotra, Armaan, Anantha, Malathi, Roosendaal, Jeroen, Leung, Ada W.Y., Plackett, David, Edwards, Katarina, Gilabert-Oriol, Roger, Bally, Marcel B.

“…A passive equilibration method which relies on addition of candidate drugs to pre-formed liposomes is described as an alternative method for preparing liposome…”
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Copper-CX-5461: A novel liposomal formulation for a small molecule rRNA synthesis inhibitor by Leung, Ada W.Y., Anantha, Malathi, Dragowska, Wieslawa H., Wehbe, Mohamed, Bally, Marcel B.

“…CX-5461 is currently in Phase I/II clinical trials for advanced hematologic malignancies and triple negative or BRCA-deficient breast cancer. The compound is…”
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Intra-vesical knot of bladder catheter in an extremely low birthweight neonate: A case report by Tang, Paula M.Y, Chung, Kenneth L.Y, Leung, Yvonne C.L, Hung, Judy W.S, Liu, Clarence C.W, Chao, Nicholas S.Y, Leung, Michael W.Y, Liu, Kelvin K.W

“…Abstract Premature and extremely low birth weight (ELBW) neonates are at high risk of developing multiple co-morbidities and often require urinary…”
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Jejunal web masquerading as intestinal malrotation in a neonate with bilious vomiting: A case report by Tang, Paula M.Y, Leung, Yvonne C.L, Hung, Judy W.S, Liu, Clarence C.W, Chung, Kenneth L.Y, Chao, Nicholas S.Y, Leung, Michael W.Y, Liu, Kelvin K.W

“…Abstract Neonatal bilious vomiting is considered as a pathological sign and warrant urgent medical attention. Upper gastro-intestinal contrast study can be…”
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Transition Metal Ions Promote the Bioavailability of Hydrophobic Therapeutics: Cu and Zn Interactions with RNA Polymerase I Inhibitor CX5461 by Prosser, Kathleen E., Leung, Ada W. Y., Harrypersad, Shane, Lewis, Andrew R., Bally, Marcel B., Walsby, Charles J.

“…Low aqueous solubility is a major barrier to the clinical application of otherwise promising drug candidates. We demonstrate that this issue can be resolved in…”
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Tri6 is a global transcription regulator in the phytopathogen Fusarium graminearum by Nasmith, Charles G, Walkowiak, Sean, Wang, Li, Leung, Winnie W Y, Gong, Yunchen, Johnston, Anne, Harris, Linda J, Guttman, David S, Subramaniam, Rajagopal

“…In F. graminearum, the transcriptional regulator Tri6 is encoded within the trichothecene gene cluster and regulates genes involved in the biosynthesis of the…”
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AN AUTOMATED ELECTRONIC RATING SYSTEM FOR THE OVERLAPPED PENTAGONS IN DEMENTIA SCREENING TESTS by Tsoi, Kelvin K.F, Leung, Nelson W.Y, Lam, Max W.Y

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Population-based evaluation of the effectiveness of two regimens for emergency contraception by Leung, Vivian W.Y, Soon, Judith A, Lynd, Larry D, Marra, Carlo A, Levine, Marc

“…Abstract Objective To estimate and compare the effectiveness of the levonorgestrel and Yuzpe regimens for hormonal emergency contraception in routine clinical…”
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CN18 Promoting acceptance and execution of advanced directives: A retrospective review in a regional hospice center in Hong Kong by Leung, W.M., Cheung, K.M., Chow, J., Chuk, E.Y.H., Leung, W.Y., Leung, C.W.L., Wong, K.H.

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Combination Therapy Showed Limited Superiority Over Monotherapy for Alzheimer Disease: A Meta-analysis of 14 Randomized Trials by Tsoi, Kelvin K.F., PhD, Chan, Joyce Y.C., MPH, Leung, Nelson W.Y, Hirai, Hoyee W., MSc, Wong, Samuel Y.S., MD, Kwok, Timothy C.Y., MD, PhD

“…Abstract Background Acetylcholinesterase inhibitor (AChEI) and memantine are recognized drug treatments with limited clinical efficacy. Combination therapy for…”
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