Search Results - "Leung, Marilyn K."

Impaired tumor necrosis factor‐α secretion by CD4 T cells during respiratory syncytial virus bronchiolitis associated with recurrent wheeze by Kitcharoensakkul, Maleewan, Bacharier, Leonard B., Yin‐Declue, Huiqing, Boomer, Jonathan S., Sajol, Geneline, Leung, Marilyn K., Wilson, Brad, Schechtman, Kenneth B., Atkinson, John P., Green, Jonathan M., Castro, Mario

“…Background Infants with severe respiratory syncytial virus (RSV) bronchiolitis have an increased risk of recurrent wheezing and asthma. We aimed to evaluate…”
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Smallpox Inhibitor of Complement Enzymes (SPICE): Dissecting Functional Sites and Abrogating Activity by Liszewski, M. Kathryn, Leung, Marilyn K, Hauhart, Richard, Fang, Celia J, Bertram, Paula, Atkinson, John P

“…Although smallpox was eradicated as a global illness more than 30 years ago, variola virus and other related pathogenic poxviruses, such as monkeypox, remain…”
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Structure and Regulatory Profile of the Monkeypox Inhibitor of Complement: Comparison to Homologs in Vaccinia and Variola and Evidence for Dimer Formation by Liszewski, M. Kathryn, Leung, Marilyn K, Hauhart, Richard, Buller, R. Mark L, Bertram, Paula, Wang, Xuefeng, Rosengard, Ariella M, Kotwal, Girish J, Atkinson, John P

“…The outbreak of monkeypox in the Unites States in the summer of 2003 was the first occurrence of this smallpox-like disease outside of Africa. This limited…”
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Smallpox Inhibitor of Complement Enzymes (SPICE): Regulation of Complement Activation on Cells and Mechanism of Its Cellular Attachment by Liszewski, M. Kathryn, Bertram, Paula, Leung, Marilyn K, Hauhart, Richard, Zhang, Lijuan, Atkinson, John P

“…Despite eradication of smallpox three decades ago, public health concerns remain due to its potential use as a bioterrorist weapon. Smallpox and other…”
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Cleavage of intracellular C3 into C3a and C3b by cathepsin L is required for human TH1 induction by Liszewski, Kathy M, Kolev, Martin, Bertram, Paula, Yamamoto, Hidekazu, Leung, Marilyn K, Atkinson, John P, Kemper, Claudia

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Modeling how CD46 deficiency predisposes to atypical hemolytic uremic syndrome by Liszewski, M. Kathryn, Leung, Marilyn K., Schraml, Barbara, Goodship, Timothy H.J., Atkinson, John P.

“…Mutations in complement regulatory proteins predispose to the development of aHUS. Approximately 50% of patients bear a mutation in one of three complement…”
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Membrane Cofactor Protein: Importance of N- and O-Glycosylation for Complement Regulatory Function by Liszewski, M. Kathryn, Leung, Marilyn K, Atkinson, John P

“…Membrane cofactor protein (MCP; CD46) is a type 1 membrane glycoprotein that inhibits complement activation on host cells. It also is a measles virus (MV)…”
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Smallpox Inhibitor of Complement Enzymes (SPICE): Dissecting Functional Sites and Abrogating Activity1 by Liszewski, M. Kathryn, Leung, Marilyn K., Hauhart, Richard, Fang, Celia J., Bertram, Paula, Atkinson, John P.

“…Although smallpox was eradicated as a global illness more than 30 years ago, variola virus and other related pathogenic poxviruses, such as monkeypox, remain…”
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Dissecting complement regulatory sites of the smallpox inhibitor of complement and abrogating function with a monoclonal antibody (44.37) by Liszewski, M. Kathryn, Leung, Marilyn K., Bertram, Paula, Atkinson, John P.

“…Abstract Public health concerns have emerged regarding use of smallpox as a bioterrorist weapon and the possibility of natural emerging infection with…”
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