Search Results - "Leung, L. H."

Transmissibility and transmission of respiratory viruses by Leung, Nancy H. L.

“…Human respiratory virus infections lead to a spectrum of respiratory symptoms and disease severity, contributing to substantial morbidity, mortality and…”
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Neutrophil activation and NETosis are the major drivers of thrombosis in heparin-induced thrombocytopenia by Perdomo, José, Leung, Halina H. L., Ahmadi, Zohra, Yan, Feng, Chong, James J. H., Passam, Freda H., Chong, Beng H.

“…Heparin-induced thrombocytopenia/thrombosis (HIT) is a serious immune reaction to heparins, characterized by thrombocytopenia and often severe thrombosis with…”
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Respiratory virus shedding in exhaled breath and efficacy of face masks by Leung, Nancy H. L., Chu, Daniel K. W., Shiu, Eunice Y. C., Chan, Kwok-Hung, McDevitt, James J., Hau, Benien J. P., Yen, Hui-Ling, Li, Yuguo, Ip, Dennis K. M., Peiris, J. S. Malik, Seto, Wing-Hong, Leung, Gabriel M., Milton, Donald K., Cowling, Benjamin J.

“…We identified seasonal human coronaviruses, influenza viruses and rhinoviruses in exhaled breath and coughs of children and adults with acute respiratory…”
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NETosis and thrombosis in vaccine-induced immune thrombotic thrombocytopenia by Leung, Halina H. L., Perdomo, Jose, Ahmadi, Zohra, Zheng, Shiying S., Rashid, Fairooj N., Enjeti, Anoop, Ting, Stephen B., Chong, James J. H., Chong, Beng H.

“…Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare yet serious adverse effect of the adenoviral vector vaccines ChAdOx1 nCoV-19 (AstraZeneca)…”
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Author Correction: Influenza antibody breadth and effector functions are immune correlates from acquisition of pandemic infection of children by Jia, Janice Z., Cohen, Carolyn A., Gu, Haogao, McLean, Milla R., Varadarajan, Raghavan, Bhandari, Nisha, Peiris, Malik, Leung, Gabriel M., Poon, Leo L. M., Tsang, Tim, Chung, Amy W., Cowling, Benjamin J., Leung, Nancy H. L., Valkenburg, Sophie A.

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Immune Thrombosis: Exploring the Significance of Immune Complexes and NETosis by Perdomo, José, Leung, Halina H. L

“…Neutrophil extracellular traps (NETs) are major contributors to inflammation and autoimmunity, playing a key role in the development of thrombotic disorders…”
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Incorporating temporal distribution of population-level viral load enables real-time estimation of COVID-19 transmission by Lin, Yun, Yang, Bingyi, Cobey, Sarah, Lau, Eric H. Y., Adam, Dillon C., Wong, Jessica Y., Bond, Helen S., Cheung, Justin K., Ho, Faith, Gao, Huizhi, Ali, Sheikh Taslim, Leung, Nancy H. L., Tsang, Tim K., Wu, Peng, Leung, Gabriel M., Cowling, Benjamin J.

“…Many locations around the world have used real-time estimates of the time-varying effective reproductive number ( R t ) of COVID-19 to provide evidence of…”
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Investigation of CD4 and CD8 T cell-mediated protection against influenza A virus in a cohort study by Tsang, Tim K, Lam, Kwok-Tai, Liu, Yinping, Fang, Vicky J, Mu, Xiaofeng, Leung, Nancy H. L, Peiris, J. S. Malik, Leung, Gabriel M, Cowling, Benjamin J, Tu, Wenwei

“…Abstract Background The protective effect of T cell-mediated immunity against influenza virus infections in natural settings remains unclear, especially in…”
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Antibody Fc receptor binding and T cell responses to homologous and heterologous immunization with inactivated or mRNA vaccines against SARS-CoV-2 by Cohen, Carolyn A., Leung, Nancy H. L., Kaewpreedee, Prathanporn, Lee, Kelly W. K., Jia, Janice Zhirong, Cheung, Alan W. L., Cheng, Samuel M. S., Mori, Masashi, Ip, Dennis K. M., Poon, Leo L. M., Peiris, J. S. Malik, Cowling, Benjamin J., Valkenburg, Sophie A.

“…Whole virion inactivated vaccine CoronaVac (C) and Spike (S) mRNA BNT162b2 (B) vaccines differ greatly in their ability to elicit neutralizing antibodies but…”
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A(H2N2) and A(H3N2) influenza pandemics elicited durable cross-reactive and protective antibodies against avian N2 neuraminidases by Liang, Zaolan, Lin, Xia, Sun, Lihong, Edwards, Kimberly M., Song, Wenjun, Sun, Hailiang, Xie, Yanmin, Lin, Fangmei, Ling, Shiman, Liang, Tingting, Xiao, Biying, Wang, Jiaqi, Li, Min, Leung, Chin-Yu, Zhu, Huachen, Bhandari, Nisha, Varadarajan, Raghavan, Levine, Min Z., Peiris, Malik, Webster, Robert, Dhanasekaran, Vijaykrishna, Leung, Nancy H. L., Cowling, Benjamin J., Webby, Richard J., Ducatez, Mariette, Zanin, Mark, Wong, Sook-San

“…Human cases of avian influenza virus (AIV) infections are associated with an age-specific disease burden. As the influenza virus N2 neuraminidase (NA) gene was…”
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Influenza antibody breadth and effector functions are immune correlates from acquisition of pandemic infection of children by Jia, Janice Z., Cohen, Carolyn A., Gu, Haogao, McLean, Milla R., Varadarajan, Raghavan, Bhandari, Nisha, Peiris, Malik, Leung, Gabriel M., Poon, Leo L. M., Tsang, Tim, Chung, Amy W., Cowling, Benjamin J., Leung, Nancy H. L., Valkenburg, Sophie A.

“…Cross-reactive antibodies with Fc receptor (FcR) effector functions may mitigate pandemic virus impact in the absence of neutralizing antibodies. In this…”
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Priming conditions shape breadth of neutralizing antibody responses to sarbecoviruses by Jia, Janice Zhirong, Tan, Chee Wah, Cheng, Samuel M. S., Gu, Haogao, Yeoh, Aileen Ying Yan, Mok, Chris Ka Pun, Wang, Yanqun, Zhao, Jincun, Leung, Nancy H. L., Cowling, Benjamin J., Poon, Leo L. M., Hui, David S. C., Wang, Linfa, Peiris, Malik, Valkenburg, Sophie A.

“…Vaccines that are broadly cross-protective against current and future SARS-CoV-2 variants of concern (VoC) or across the sarbecoviruses subgenus remain a…”
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Quantification of Influenza Virus RNA in Aerosols in Patient Rooms by Leung, Nancy H L, Zhou, Jie, Chu, Daniel K W, Yu, Han, Lindsley, William G, Beezhold, Donald H, Yen, Hui-Ling, Li, Yuguo, Seto, Wing-Hong, Peiris, Joseph S M, Cowling, Benjamin J

“…The potential for human influenza viruses to spread through fine particle aerosols remains controversial. The objective of our study was to determine whether…”
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Identification of Epigallocatechin-3- Gallate as an Inhibitor of Phosphoglycerate Mutase 1 by Li, Xiaoguang, Tang, Shuai, Wang, Qian-Qian, Leung, Elaine L-H, Jin, Hongyue, Huang, Yongzhuo, Liu, Jia, Geng, Meiyu, Huang, Min, Yuan, Shengtao, Yao, Xiao-Jun, Ding, Jian

“…Targeting metabolic enzymes is believed to provide new therapeutic opportunities for cancer therapy. Phosphoglycerate mutase 1 (PGAM1) is a glycolytic enzyme…”
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Author Correction: Respiratory virus shedding in exhaled breath and efficacy of face masks by Leung, Nancy H. L., Chu, Daniel K. W., Shiu, Eunice Y. C., Chan, Kwok-Hung, McDevitt, James J., Hau, Benien J. P., Yen, Hui-Ling, Li, Yuguo, Ip, Dennis K. M., Peiris, J. S. Malik, Seto, Wing-Hong, Leung, Gabriel M., Milton, Donald K., Cowling, Benjamin J.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Comparison of alternative full and brief versions of functional status scales among older adults in China by Reich, Jeremy, Thompson, Mark G, Cowling, Benjamin J, Iuliano, A Danielle, Greene, Carolyn, Chen, Yuyun, Phadnis, Rachael, Leung, Nancy H L, Song, Ying, Fang, Vicky J, Xu, Cuiling, Dai, Qigang, Zhang, Jun, Zhang, Hongjun, Havers, Fiona

“…Brief assessments of functional status for community-dwelling older adults are needed given expanded interest in the measurement of functional decline. As part…”
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INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma by Yang, N, Leung, E L-H, Liu, C, Li, L, Eguether, T, Jun Yao, X-J, Jones, E C, Norris, D A, Liu, A, Clark, R A, Roop, D R, Pazour, G J, Shroyer, K R, Chen, J

“…Inturned (INTU), a cilia and planar polarity effector, performs prominent ciliogenic functions during morphogenesis, such as in the skin. INTU is expressed in…”
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Reply to the letter to the editor regarding: A prospective randomized trial evaluating the outcomes of transanal hemorrhoidal dearterialization versus tissue-selecting technique by Leung, L. H.

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New WHO proposed terminology for respiratory pathogen transmission by Leung, Nancy H. L., Milton, Donald K.

“…A WHO report suggests the terms ‘airborne transmission/inhalation’, ‘direct deposition’ and ‘infectious respiratory particles’ for describing transmission…”
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Honokiol Inhibits Proliferation, Invasion and Induces Apoptosis Through Targeting Lyn Kinase in Human Lung Adenocarcinoma Cells by Dai, Xi, Li, Run-Ze, Jiang, Ze-Bo, Wei, Chun-Li, Luo, Lian-Xiang, Yao, Xiao-Jun, Li, Guo-Ping, Leung, Elaine L-H

“…Honokiol is a natural compound with small molecular structure and extracted from bark of magnolia trees. The biological activities of honokiol include…”
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