Search Results - "Leung, Cheuk H."
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Pathologic Processing of Lung Cancer Resection Specimens After Neoadjuvant Therapy
Published in Modern pathology (01-01-2024)“…Neoadjuvant treatment of non-small cell lung cancer challenges the traditional processing of pathology specimens. Induction therapy before resection allows…”
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Surgical outcomes after neoadjuvant nivolumab or nivolumab with ipilimumab in patients with non–small cell lung cancer
Published in The Journal of thoracic and cardiovascular surgery (01-11-2022)“…Surgical outcomes for non–small cell lung cancer after neoadjuvant immune checkpoint inhibitors continue to be debated. We assessed perioperative outcomes of…”
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Breast and Lung Effusion Survival Score Models: Improving Survival Prediction in Patients With Malignant Pleural Effusion and Metastasis
Published in Chest (01-09-2021)“…Evidence-based guidelines recommend management strategies for malignant pleural effusions (MPEs) based on life expectancy. Existent risk-prediction rules do…”
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Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer
Published in Nature communications (19-08-2021)“…Radiographic imaging is the standard approach for evaluating the disease involvement of lymph nodes in patients with operable NSCLC although the impact of…”
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Surgical outcomes after chemotherapy plus nivolumab and chemotherapy plus nivolumab and ipilimumab in patients with non–small cell lung cancer
Published in The Journal of thoracic and cardiovascular surgery (01-04-2024)“…Chemotherapy plus nivolumab is the standard of care neoadjuvant treatment for patients with resectable stage IB to IIIA non–small cell lung cancer. The…”
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Clinicopathological analysis of ATRX, DAXX and NOTCH receptor expression in angiosarcomas
Published in Histopathology (01-01-2018)“…Aims Multiple genetic alterations, including alternative lengthening of telomeres (ALT) and NOTCH mutations, have been described in angiosarcoma. Loss of…”
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Clinical Effectiveness and Safety of Anti-PD-(L)1 Therapy Among Older Adults With Advanced Non-Small Cell Lung Cancer
Published in Clinical lung cancer (01-05-2022)“…As a result of the approval of several immune checkpoint inhibitors (ICIs) for the treatment of non-small cell lung cancer (NSCLC), many older adults are being…”
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The immune landscape of undifferentiated pleomorphic sarcoma
Published in Frontiers in oncology (12-10-2022)“…Introduction Undifferentiated pleomorphic sarcoma (UPS) can be associated with a relatively dense immune infiltration. Immune checkpoint inhibitors (anti-PD1,…”
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The role of phosphorylated signal transducer and activator of transcription 3 (pSTAT3) in peripheral nerve sheath tumours
Published in Histopathology (01-05-2017)“…Aims STAT3 is a pro‐oncogenic transcription factor that requires phosphorylation for transcriptional activation. The aim of this study was to evaluate the role…”
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Impact of select actionable genomic alterations on efficacy of neoadjuvant immunotherapy in resectable non-small cell lung cancer
Published in Journal for immunotherapy of cancer (23-10-2024)“…Neoadjuvant immune checkpoint inhibitors (ICIs) have improved survival outcomes compared with chemotherapy in resectable non-small cell lung cancer (NSCLC)…”
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Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial
Published in Nature medicine (01-03-2021)“…Ipilimumab improves clinical outcomes when combined with nivolumab in metastatic non-small cell lung cancer (NSCLC), but its efficacy and impact on the immune…”
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Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial
Published in Nature medicine (01-03-2023)“…Neoadjuvant ipilimumab + nivolumab (Ipi+Nivo) and nivolumab + chemotherapy (Nivo+CT) induce greater pathologic response rates than CT alone in patients with…”
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13
Breast and Lung Effusion Survival Score Models
Published in Chest (01-09-2021)“…Evidence-based guidelines recommend management strategies for malignant pleural effusions (MPEs) based on life expectancy. Existent risk-prediction rules do…”
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Abstract 3857: Characterization of immune cell biomarkers in undifferentiated pleomorphic sarcoma
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Background: Undifferentiated pleomorphic sarcoma (UPS) are genetically complex sarcomas often showing a relatively higher immune infiltration among…”
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