Search Results - "Leung, B P"

Sex-specific differences in risk factors for sarcopenia amongst community-dwelling older adults by Tay, L., Ding, Y. Y., Leung, B. P., Ismail, N. H., Yeo, A., Yew, S., Tay, K. S., Tan, C. H., Chong, M. S.

“…With considerable variation including potential sex-specific differential rate of skeletal muscle loss, identifying modifiable factors for sarcopenia will be…”
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Interleukin 27 attenuates collagen-induced arthritis by Niedbala, W, Cai, B, Wei, X, Patakas, A, Leung, B P, McInnes, I B, Liew, F Y

“…To investigate the potential role of interleukin (IL) 27 in rheumatoid arthritis (RA) by examining the expression of IL27 in the articular joints of patients…”
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Enhanced expression of interferon-inducible protein-10 correlates with disease activity and clinical manifestations in systemic lupus erythematosus by Kong, K.O, Tan, A.W, Thong, B.Y.H, Lian, T.Y, Cheng, Y.K, Teh, C.L, Koh, E.T, Chng, H.H, Law, W.G, Lau, T.C, Leong, K.P, Leung, B.P, Howe, H.S

“…Our objective was to investigate the serum levels of interferon-inducible protein-10 (IP-10) in systemic lupus erythematosus (SLE) and their correlation with…”
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A Role for IL-18 in Neutrophil Activation by Leung, Bernard P, Culshaw, Shauna, Gracie, J. Alastair, Hunter, David, Canetti, Claudio A, Campbell, Carol, Cunha, Fernando, Liew, Foo Y, McInnes, Iain B

“…IL-18 expression and functional activity has been identified in several autoimmune and infectious diseases. To clarify the potential role of IL-18 during early…”
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Serum Myostatin and IGF-1 as Gender-Specific Biomarkers of Frailty and Low Muscle Mass in Community-Dwelling Older Adults by Chew, Justin, Tay, L., Lim, J. P., Leung, B. P., Yeo, A., Yew, S., Ding, Y. Y., Lim, W. S.

“…Objectives To investigate serum myostatin (absolute and normalized for total body lean mass (TBLM)) and IGF-1 as biomarkers of frailty and low relative…”
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Shigella sonnei utilises colicins during inter-bacterial competition by Leung, P B, Matanza, X M, Roche, B, Ha, K P, Cheung, H C, Appleyard, S, Collins, T, Flanagan, O, Marteyn, B S, Clements, A

“…The mammalian colon is one of the most densely populated habitats currently recognised, with 10 -10 commensal bacteria per gram of colonic contents. Enteric…”
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Reduced Incidence and Severity of Collagen-Induced Arthritis in Mice Lacking IL-18 by Wei, Xiao-qing, Leung, Bernard P, Arthur, Helen M. L, McInnes, Iain B, Liew, Foo Y

“…We have recently reported the presence and a potential proinflammatory role of IL-18 in the synovium of patients with rheumatoid arthritis. To obtain direct…”
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Thymosin β 4 sulfoxide is an anti-inflammatory agent generated by monocytes in the presence of glucocorticoids by Lawrence, A.J, Young, J.D, MacLean, A.G, Leung, B.P, McInnes, I.B, Canas, B, Pappin, D.J.C, Stevenson, R.D

“…The possibility that glucocorticoids upregulate the expression of anti-inflammatory mediators is an exciting prospect for therapy in inflammatory diseases,…”
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Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients by McInnes, I B, Leung, B P, Field, M, Wei, X Q, Huang, F P, Sturrock, R D, Kinninmonth, A, Weidner, J, Mumford, R, Liew, F Y

“…We have demonstrated spontaneous nitric oxide (NO) production by primary synovial cultures from rheumatoid (RA) and osteoarthritis patients. Increased NO…”
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Transforming growth factor beta-1 and gene polymorphisms in oriental ankylosing spondylitis by Howe, H. S., Cheung, P. L., Kong, K. O., Badsha, H., Thong, B. Y. H., Leong, K. P., Koh, E. T., Lian, T. Y., Cheng, Y. K., Lam, S., Teo, D., Lau, T. C., Leung, B. P.

“…Objectives. To study serum levels of transforming growth factor beta-1 (TGFβ1) and the expression of TGFβ1 in in vitro peripheral blood mononuclear cell (PBMC)…”
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The Sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo by Wei Xq, Orchardson, M, Gracie, J A, Leung, B P, Gao Bm, Guan, H, Niedbala, W, Paterson, G K, McInnes, I B, Liew, F Y

“…IL-15 is a pleiotropic cytokine that plays important roles in both innate and adaptive immunity. It is associated with a range of immunopathology, including…”
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Association of nutrition and immune-endocrine dysfunction with muscle mass and performance in cognitively impaired older adults by Tay, L., Leung, B.P., Wee, S., Tay, K.S., Ali, N., Chan, M., Lim, W.S.

“…•Muscle quality beyond muscle mass impacts on functional performance in cognitively impaired older adults.•Malnutrition is associated with both pre-sarcopenia…”
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Bilateral obstacle optimal control for a quasilinear elliptic variational inequality with a source term by Ye, Yuquan, Chan, Chi Kin, Leung, B.P.K., Chen, Q.

“…In this paper we consider an obstacle control problem where the state satisfies a quasilinear elliptic variational inequality with a source term and the…”
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Enhancing product development through a dynamic information interchange approach by Lee, C. K. M., Lau, H. C. W., Leung, B. P. K., Ho, G. T. S., Choy, K. L.

“…In today's increasingly competitive environment, firms are experiencing growing pressure to reduce the product development lead time to meet market…”
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Associations of B cell‐activating factor (BAFF) and anti‐BAFF autoantibodies with disease activity in multi‐ethnic Asian systemic lupus erythematosus patients in Singapore by Howe, H. S., Thong, B. Y. H., Kong, K. O., Chng, H. H., Lian, T. Y., Chia, F. L., Tay, K. S. S., Lau, T. C., Law, W. G., Koh, E. T., Leung, B. P.

“…Summary To measure the levels of B cell‐activating factor (BAFF) and endogenous anti‐BAFF autoantibodies in a cohort of multi‐ethnic Asian systemic lupus…”
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P1683: PERSISTENT HYPERCOAGULABILITY, ENDOTHELIOPATHY AND INFLAMMATION IN COVID‐19 PATIENTS APPROXIMATING 1 YEAR AFTER RECOVERY by Fan, B. E., Wong, S. W., Sum, C. L. L., Lim, G. H., Leung, B. P., Dalan, R., Young, B. E., Lye, D. C., Cheung, C., Ramanathan, K., Tan, C. W., Yap, E. S., Chia, Y. W.

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A Novel Anti-Inflammatory Role of Simvastatin in a Murine Model of Allergic Asthma by McKay, Anne, Leung, Bernard P, McInnes, Iain B, Thomson, Neil C, Liew, Foo Y

“…Statins, the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, are effective serum cholesterol-lowering agents in clinical practice, and they may also have…”
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The effect of nerve mobilization exercise in patients with rheumatoid arthritis: a pilot study by Lo, C-N, Xia, G, Leung, B P

“…Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic inflammation of the joints. The neurogenic inflammatory mechanism plays an…”
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A Novel Anti-Inflammatory Role for Simvastatin in Inflammatory Arthritis by Leung, Bernard P, Sattar, Naveed, Crilly, Anne, Prach, Morag, McCarey, David W, Payne, Helen, Madhok, Rajan, Campbell, Carol, Gracie, J. Alastair, Liew, Foo Y, McInnes, Iain B

“…3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors (statins) exert favorable effects on lipoprotein metabolism, but may also possess anti-inflammatory…”
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A Novel Therapeutic Approach Targeting Articular Inflammation Using the Filarial Nematode-Derived Phosphorylcholine-Containing Glycoprotein ES-62 by McInnes, Iain B, Leung, Bernard P, Harnett, Margaret, Gracie, J. Alastair, Liew, Foo Y, Harnett, William

“…Understanding modulation of the host immune system by pathogens offers rich therapeutic potential. Parasitic filarial nematodes are often tolerated in human…”
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