Search Results - "Leuchtmann, Aurel B"
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The Role of the Skeletal Muscle Secretome in Mediating Endurance and Resistance Training Adaptations
Published in Frontiers in physiology (12-08-2021)“…Exercise, in the form of endurance or resistance training, leads to specific molecular and cellular adaptions not only in skeletal muscles, but also in many…”
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Resistance training preserves high-intensity interval training induced improvements in skeletal muscle capillarization of healthy old men: a randomized controlled trial
Published in Scientific reports (20-04-2020)“…Skeletal muscle capillarization is a determining factor in gas and metabolite exchange, while its impairments may contribute to the development of sarcopenia…”
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Effects of high‐resistance wheel running on hallmarks of endurance and resistance training adaptations in mice
Published in Physiological reports (01-06-2023)“…Exercise effectively promotes and preserves cardiorespiratory, neuromuscular, metabolic, and cognitive functions throughout life. The molecular mechanisms…”
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Interleukin‐6 potentiates endurance training adaptation and improves functional capacity in old mice
Published in Journal of cachexia, sarcopenia and muscle (01-04-2022)“…Background Interventions to preserve functional capacities at advanced age are becoming increasingly important. So far, exercise provides the only means to…”
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Author Correction: Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle
Published in Nature communications (27-04-2022)Get full text
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Pharmacological targeting of age-related changes in skeletal muscle tissue
Published in Pharmacological research (01-04-2020)“…[Display omitted] Sarcopenia, the age-related loss of skeletal muscle mass and function, increases the risk of developing chronic diseases in older individuals…”
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Impaired age-associated mitochondrial translation is mitigated by exercise and PGC-1α
Published in Proceedings of the National Academy of Sciences - PNAS (05-09-2023)“…Sarcopenia, the age-related loss of skeletal muscle mass and function, can dramatically impinge on quality of life and mortality. While mitochondrial…”
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Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle
Published in Nature communications (19-04-2022)“…Preserving skeletal muscle function is essential to maintain life quality at high age. Calorie restriction (CR) potently extends health and lifespan, but is…”
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RNA-bound PGC-1α controls gene expression in liquid-like nuclear condensates
Published in Proceedings of the National Academy of Sciences - PNAS (07-09-2021)“…Plasticity of cells, tissues, and organs is controlled by the coordinated transcription of biological programs. However, the mechanisms orchestrating such…”
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