Search Results - "Leuchs, Laura"
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The biological classification of mental disorders (BeCOME) study: a protocol for an observational deep-phenotyping study for the identification of biological subtypes
Published in BMC psychiatry (11-05-2020)“…A major research finding in the field of Biological Psychiatry is that symptom-based categories of mental disorders map poorly onto dysfunctions in brain…”
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Measuring the conditioned response: A comparison of pupillometry, skin conductance, and startle electromyography
Published in Psychophysiology (01-01-2019)“…In human fear conditioning studies, different physiological readouts can be used to track conditioned responding during fear learning. Commonly employed…”
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Disentangling reward anticipation with simultaneous pupillometry / fMRI
Published in NeuroImage (Orlando, Fla.) (01-09-2018)“…The reward system may provide an interesting intermediate phenotype for anhedonia in affective disorders. Reward anticipation is characterized by an increase…”
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Neural correlates of pupil dilation during human fear learning
Published in NeuroImage (Orlando, Fla.) (15-02-2017)“…Fear conditioning and extinction are prevailing experimental and etiological models for normal and pathological anxiety. Pupil dilations in response to…”
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Spontaneous pupil dilations during the resting state are associated with activation of the salience network
Published in NeuroImage (Orlando, Fla.) (01-10-2016)“…Resting state functional magnetic resonance imaging (rs-fMRI) is increasingly applied for the development of functional biomarkers in brain disorders. Recent…”
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No robust differences in fear conditioning between patients with fear-related disorders and healthy controls
Published in Behaviour research and therapy (01-06-2020)“…Fear conditioning and extinction serve as a dominant model for the development and maintenance of pathological anxiety, particularly for phasic fear to…”
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Multi-echo EPI of human fear conditioning reveals improved BOLD detection in ventromedial prefrontal cortex
Published in NeuroImage (Orlando, Fla.) (01-08-2017)“…Standard T2* weighted functional magnetic resonance imaging (fMRI) performed with echo-planar imaging (EPI) suffers from signal loss in the ventromedial…”
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Free-viewing gaze patterns reveal a mood-congruency bias in MDD during an affective fMRI/eye-tracking task
Published in European archives of psychiatry and clinical neuroscience (01-04-2024)“…Major depressive disorder (MDD) has been related to abnormal amygdala activity during emotional face processing. However, a recent large-scale study ( n =…”
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Data-Driven Pupil Response Profiles as Transdiagnostic Readouts for the Detection of Neurocognitive Functioning in Affective and Anxiety Disorders
Published in Biological psychiatry : cognitive neuroscience and neuroimaging (01-06-2024)“…Neurocognitive functioning is a relevant transdiagnostic dimension in psychiatry. As pupil size dynamics track cognitive load during a working memory task, we…”
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