Search Results - "Lettieri‐Barbato, Daniele"
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Soybean Oil‐Based 3D Printed Mesh Designed for Guided Bone Regeneration (GBR) in Oral Surgery
Published in Macromolecular bioscience (01-05-2024)“…This study aims to obtain a cyto‐compatible 3D printable bio‐resin for the manufacturing of meshes designed from acquired real patients’ bone defect to be used…”
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Frataxin deficiency induces lipid accumulation and affects thermogenesis in brown adipose tissue
Published in Cell death & disease (23-01-2020)“…Decreased expression of mitochondrial frataxin (FXN) causes Friedreich’s ataxia (FRDA), a neurodegenerative disease with type 2 diabetes (T2D) as severe…”
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Glutathione Decrement Drives Thermogenic Program In Adipose Cells
Published in Scientific reports (11-08-2015)“…Adipose tissue metabolically adapts to external stimuli. We demonstrate that the induction of the thermogenic program in white adipocytes, through cold…”
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Protocol for detecting mitochondria extracellular vesicles of brown adipose tissue in mice
Published in STAR protocols (20-09-2024)“…Brown adipose tissue (BAT) is mitochondria rich, enabling high oxidative metabolism for non-shivering thermogenesis. The release of large/small extracellular…”
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Metformin protects skeletal muscle from cardiotoxin induced degeneration
Published in PloS one (02-12-2014)“…The skeletal muscle tissue has a remarkable capacity to regenerate upon injury. Recent studies have suggested that this regenerative process is improved when…”
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Glutathione transferase P silencing promotes neuronal differentiation of retinal R28 cells
Published in Journal of cellular physiology (01-09-2019)“…Glutathione transferases (GSTs) play an important role in retinal pathophysiology. Within this family, the GSTP isoform is known as an endogenous regulator of…”
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Molecular and histological traits of reduced lysosomal acid lipase activity in the fatty liver
Published in Cell death & disease (18-11-2021)“…Recent studies demonstrated reduced blood lysosomal acid lipase (LAL) activity in patients with nonalcoholic fatty liver disease (NAFLD). We aimed to verify…”
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Adipocyte metabolism is improved by TNF receptor-targeting small RNAs identified from dried nuts
Published in Communications biology (21-08-2019)“…There is a growing interest in therapeutically targeting the inflammatory response that underlies age-related chronic diseases including obesity and type 2…”
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Inhibition of Age-Related Cytokines Production by ATGL: A Mechanism Linked to the Anti-Inflammatory Effect of Resveratrol
Published in Mediators of Inflammation (01-01-2014)“…Ageing is characterized by the expansion and the decreased vascularization of visceral adipose tissue (vAT), disruption of metabolic activities, and decline of…”
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Redox control of non-shivering thermogenesis
Published in Molecular metabolism (Germany) (01-07-2019)“…Thermogenic adipocytes reorganize their metabolism during cold exposure. Metabolic reprogramming requires readily available bioenergetics substrates, such as…”
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The multifaceted role of nitric oxide synthases in mitochondrial biogenesis and cell differentiation
Published in Communicative & integrative biology (01-03-2015)“…Nitric oxide (NO) is physiologically synthetized by a family of enzymes called NO synthases (NOSs). NO is a pleiotropic second messenger having a fundamental…”
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Pushing the Limits of Cancer Therapy: The Nutrient Game
Published in Frontiers in oncology (08-05-2018)“…The standard cancer treatments include chemotherapy, radiotherapy, or their combination, which are generally associated with a multitude of side effects…”
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Feast and Famine: Adipose Tissue Adaptations for Healthy Aging
Published in Ageing research reviews (01-07-2016)“…Highlights • Time-controlled fasting improves mitochondrial metabolism of fat cells. • Mitochondrial flexibility maintains adipose tissue functionality. •…”
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The role of nNOS and PGC-1α in skeletal muscle cells
Published in Journal of cell science (15-11-2014)“…Neuronal nitric oxide synthase (nNOS) and peroxisome proliferator activated receptor γ co-activator 1α (PGC-1α) are two fundamental factors involved in the…”
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The Nrf2 induction prevents ferroptosis in Friedreich's Ataxia
Published in Redox biology (01-01-2021)“…Ferroptosis is an iron-dependent cell death caused by impaired glutathione metabolism, lipid peroxidation and mitochondrial failure. Emerging evidences report…”
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Time-controlled fasting prevents aging-like mitochondrial changes induced by persistent dietary fat overload in skeletal muscle
Published in PloS one (09-05-2018)“…A large body of evidence suggests that persistent dietary fat overload causes mitochondrial dysfunction and systemic metabolic gridlock. Mitochondrial and…”
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Lipophagy Impairment Is Associated With Disease Progression in NAFLD
Published in Frontiers in physiology (17-07-2020)“…Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in Western countries and is associated with aging and features of…”
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Editorial: Advances in metabolic mechanisms of aging and its related diseases, Volume II
Published in Frontiers in physiology (24-01-2023)Get full text
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Managing lipid metabolism in proliferating cells: New perspective for metformin usage in cancer therapy
Published in Biochimica et biophysica acta (01-04-2014)“…Cancer cells metabolically adapt to undergo cellular proliferation. Lipids, besides their well-known role as energy storage, represent the major building…”
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FoxO1 at the nexus between fat catabolism and longevity pathways
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-10-2014)“…Adipose tissue should not be considered a simple fat sink but a specialized system that promptly and dynamically responds to variations of nutrients, to fulfil…”
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