Search Results - "Letondal, Patricia"

CD4 T cells target colorectal cancer antigens upregulated by oxaliplatin by Galaine, Jeanne, Turco, Célia, Vauchy, Charline, Royer, Bernard, Mercier‐Letondal, Patricia, Queiroz, Lise, Loyon, Romain, Mouget, Virginie, Boidot, Romain, Laheurte, Caroline, Lakkis, Zaher, Jary, Marine, Adotévi, Olivier, Borg, Christophe, Godet, Yann

“…Immune checkpoint blockade has proven its efficacy in hypermutated subtypes of metastatic colorectal cancers (mCRC). Immunogenic potential can also be observed…”
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Validation of a method evaluating T cell metabolic potential in compliance with ICH Q2 (R1) by Mercier-Letondal, Patricia, Marton, Chrystel, Godet, Yann, Galaine, Jeanne

“…Metabolic cell features are able to give reliable information on cell functional state. Thus, metabolic potential assessment of T cells in malignancy setting…”
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Responsible scientific research at Inserm: a field study by Estienne, Monique, Chevalier, Catherine, Fagard, Catherine, Letondal, Patricia, Giesen, Eva

“…In France, Inserm (National Institute of Health And Medical Research) puts considerable effort into scientific integrity and quality management since more than…”
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Characterization of atypical T cells generated during ex vivo expansion process for T cell-based adoptive immunotherapy by Mercier-Letondal, Patricia, Kumar, Abhishek, Marton, Chrystel, Bonnefoy, Francis, Fredon, Maxime, Boullerot, Laura, Dehecq, Barbara, Adotévi, Olivier, Godet, Yann, Galaine, Jeanne

“…Engineered T cell-based adoptive immunotherapies met promising success for the treatment of hematological malignancies. Nevertheless, major hurdles remain to…”
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Regulatory T-cell expansion and function do not account for the impaired alloreactivity of ex vivo-expanded T cells by Montcuquet, Nicolas, Mercier-Letondal, Patricia, Perruche, Sylvain, Duperrier, Anne, Couturier, Mélanie, Bouchekioua, Abdelghani, Bonyhadi, Mark, Ferrand, Christophe, Tiberghien, Pierre, Robinet, Eric

“…CD3- and CD28-activated T cells expanded for 12 days ex vivo to produce suicide gene-modified T cells are hyporesponsive to alloantigens. To investigate…”
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SALL4 oncogene is an immunogenic antigen presented in various HLA-DR contexts by Kroemer, Marie, Spehner, Laurie, Mercier-Letondal, Patricia, Boullerot, Laura, Kim, Stefano, Jary, Marine, Galaine, Jeanne, Picard, Emilie, Ferrand, Christophe, Nguyen, Thierry, Larosa, Fabrice, Adotévi, Olivier, Godet, Yann, Borg, Christophe

“…Purpose: To investigate the immunoprevalence of SALL4-derived peptides in healthy volunteers and cancer patients. Experimental Design: A multistep approach…”
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An unmet need: Harmonization of IL-7 and IL-15 combination for the ex vivo generation of minimally differentiated T cells by Marton, Chrystel, Mercier-Letondal, Patricia, Galaine, Jeanne, Godet, Yann

“…•Cytokine mass concentration does not correlate with biological activity.•Universal reporting of cytokine activity against calibrated standards is…”
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Homeostatic cytokines tune naivety and stemness of cord blood-derived transgenic T cells by Marton, Chrystel, Mercier-Letondal, Patricia, Loyon, Romain, Adotévi, Olivier, Borg, Christophe, Galaine, Jeanne, Godet, Yann

“…Engineered T-cell therapies have proven to be successful in cancer and their clinical effectiveness is directly correlated with the infused T-cell…”
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IL-21-Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor-Dependent Manner by Loyon, Romain, Picard, Emilie, Mauvais, Olivier, Queiroz, Lise, Mougey, Virginie, Pallandre, Jean-René, Galaine, Jeanne, Mercier-Letondal, Patricia, Kellerman, Guillaume, Chaput, Nathalie, Wijdenes, John, Adotévi, Olivier, Ferrand, Christophe, Romero, Pedro, Godet, Yann, Borg, Christophe

“…NK cells are critical for innate immunity-mediated protection. The main roles of NK cells rely on their cytotoxic functions or depend on the tuning of Th1…”
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Personalized identification of tumor-associated immunogenic neoepitopes in hepatocellular carcinoma in complete remission after sorafenib treatment by Vrecko, Sindy, Guenat, David, Mercier-Letondal, Patricia, Faucheu, Hugues, Dosset, Magalie, Royer, Bernard, Galaine, Jeanne, Boidot, Romain, Kim, Stefano, Jary, Marine, Adotévi, Olivier, Borg, Christophe, Godet, Yann

“…Sorafenib, a multi-targeted kinase inhibitor, is the current standard systemic treatment for advanced hepatocellular carcinoma. Sorafenib has anti-angiogenic…”
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CD3+CD20+ cells may be an artifact of flow cytometry: Comment on the article by Wilk et al by Henry, Carole, Ramadan, Abdulraouf, Montcuquet, Nicolas, Pallandre, Jean‐René, Mercier‐Letondal, Patricia, Deschamps, Marina, Tiberghien, Pierre, Ferrand, Christophe, Robinet, Eric

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Early immune response against retrovirally transduced herpes simplex virus thymidine kinase-expressing gene-modified T cells coinfused with a T cell-depleted marrow graft: an altered immune response? by Mercier-Letondal, Patricia, Deschamps, Marina, Sauce, Delphine, Certoux, Jean Marie, Milpied, Noël, Lioure, Bruno, Cahn, Jean-Yves, Deconinck, Eric, Ferrand, Christophe, Tiberghien, Pierre, Robinet, Eric

“…Administration of herpes simplex thymidine kinase (HSV-tk)-expressing, gene-modified T cells (GMCs) with T cell-depleted bone marrow transplantation (TCD-BMT)…”
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Alloreactivity of ex vivo -expanded T cells is correlated with expansion and CD4/CD8 ratio by Mercier-Letondal, P, Montcuquet, N, Sauce, D, Certoux, J.-M, Jeanningros, S, Ferrand, C, Bonyhadi, M, Tiberghien, P, Robinet, E., PhD

“…Background We have demonstrated previously that retroviral-mediated transfer of a suicide gene into bone marrow (BM) donor T cells allows an efficient control…”
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CD3+ CD20+ cells may be an artifact of flow cytometry by Henry, Carole, Ramadan, Abdulraouf, Montcuquet, Nicolas, Pallandre, Jean-René, Mercier-Letondal, Patricia, Deschamps, Marina, Tiberghien, Pierre, Ferrand, Christophe, Robinet, Eric

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