Search Results - "Letko Khait, Nitzan"

Therapy-Educated Mesenchymal Stem Cells Enrich for Tumor-Initiating Cells by Timaner, Michael, Letko-Khait, Nitzan, Kotsofruk, Ruslana, Benguigui, Madeleine, Beyar-Katz, Ofrat, Rachman-Tzemah, Chen, Raviv, Ziv, Bronshtein, Tomer, Machluf, Marcelle, Shaked, Yuval

“…Stromal cells residing in the tumor microenvironment contribute to the development of therapy resistance. Here we show that chemotherapy-educated mesenchymal…”
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Wielding the Double‐Edged Sword of Inflammation: Building Biomaterial‐Based Strategies for Immunomodulation in Ischemic Stroke Treatment by Letko Khait, Nitzan, Ho, Eric, Shoichet, Molly S.

“…Stroke is a leading cause of disability with no current treatment to regenerate lost brain tissue. Innovative preclinical and clinical trials have attempted to…”
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Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain by Letko Khait, Nitzan, Zuccaro, Sabrina, Abdo, Dhana, Cui, Hong, Siu, Ricky, Ho, Eric, Morshead, Cindi M., Shoichet, Molly S.

“…Injuries to the central nervous system, such as stroke and traumatic spinal cord injury, result in an aggregate scar that both limits tissue degeneration and…”
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Nanoghosts as a Novel Natural Nonviral Gene Delivery Platform Safely Targeting Multiple Cancers by Kaneti, Limor, Bronshtein, Tomer, Malkah Dayan, Natali, Kovregina, Inna, Letko Khait, Nitzan, Lupu-Haber, Yael, Fliman, Miguel, Schoen, Beth W, Kaneti, Galoz, Machluf, Marcelle

“…Nanoghosts derived from mesenchymal stem cells and retaining their unique surface-associated tumor-targeting capabilities were redesigned as a selective and…”
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Nano-Ghosts: Biomimetic membranal vesicles, technology and characterization by Oieni, Jacopo, Levy, Lior, Letko Khait, Nitzan, Yosef, Liat, Schoen, Beth, Fliman, Miguel, Shalom-Luxenburg, Hagit, Malkah Dayan, Natali, D'Atri, Domenico, Cohen Anavy, Noa, Machluf, Marcelle

“…•Investigation of Nano-Ghosts manufacturing-process robustness.•Examination of post-production shelf-life through stability and storage studies.•Demonstration…”
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Radiolabeling of cell membrane-based nano-vesicles with 14C-linoleic acid for robust and sensitive quantification of their biodistribution by Letko Khait, Nitzan, Malkah, Natali, Kaneti, Galoz, Fried, Lital, Cohen Anavy, Noa, Bronshtein, Tomer, Machluf, Marcelle

“…The rapid development of biomimetic cell membrane-based nanoparticles is still overshadowed by many practical challenges, one of which is the difficulty to…”
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Reengineering biocatalysts: Computational redesign of chondroitinase ABC improves efficacy and stability by Hettiaratchi, Marian H, O'Meara, Matthew J, O'Meara, Teresa R, Pickering, Andrew J, Letko-Khait, Nitzan, Shoichet, Molly S

“…Maintaining biocatalyst stability and activity is a critical challenge. Chondroitinase ABC (ChABC) has shown promise in central nervous system (CNS)…”
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Radiolabeling of cell membrane-based nano-vesicles with 14 C-linoleic acid for robust and sensitive quantification of their biodistribution by Letko Khait, Nitzan, Malkah, Natali, Kaneti, Galoz, Fried, Lital, Cohen Anavy, Noa, Bronshtein, Tomer, Machluf, Marcelle

“…The rapid development of biomimetic cell membrane-based nanoparticles is still overshadowed by many practical challenges, one of which is the difficulty to…”
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