Search Results - "Letizia Leocani"

Apparatus design and behavioural testing protocol for the evaluation of spatial working memory in mice through the spontaneous alternation T-maze by d’Isa, Raffaele, Comi, Giancarlo, Leocani, Letizia

“…Spatial working memory can be assessed in mice through the spontaneous alternation T-maze test. The T-maze is a T-shaped apparatus featuring a stem (start arm)…”
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Dementia care and COVID-19 pandemic: a necessary digital revolution by Cuffaro, Luca, Di Lorenzo, Francesco, Bonavita, Simona, Tedeschi, Gioacchino, Leocani, Letizia, Lavorgna, Luigi

“…Due to the COVID-19 pandemic, most memory clinics have had to suspend their activities. On the other hand, international dementia experts have recommended to…”
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Telemedicine and the challenge of epilepsy management at the time of COVID-19 pandemic by Brigo, Francesco, Bonavita, Simona, Leocani, Letizia, Tedeschi, Gioacchino, Lavorgna, Luigi

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Functional and morphological changes of the retinal vessels in Alzheimer’s disease and mild cognitive impairment by Querques, Giuseppe, Borrelli, Enrico, Sacconi, Riccardo, De Vitis, Luigi, Leocani, Letizia, Santangelo, Roberto, Magnani, Giuseppe, Comi, Giancarlo, Bandello, Francesco

“…Imaging and histopathological studies have demonstrated that structural changes of the retina affect subjects with Alzheimer’s disease (AD) or mild cognitive…”
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Beyond rehabilitation in MS: Insights from non-invasive brain stimulation by Leocani, Letizia, Chieffo, Raffaella, Gentile, Antonietta, Centonze, Diego

“…Although the number of disease-modifying treatments for people with multiple sclerosis (pwMS) has meaningfully increased in the past years, targeting repair or…”
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Subclinical neurodegeneration in multiple sclerosis and neuromyelitis optica spectrum disorder revealed by optical coherence tomography by Pisa, Marco, Ratti, Francesco, Vabanesi, Marco, Radaelli, Marta, Guerrieri, Simone, Moiola, Lucia, Martinelli, Vittorio, Comi, Giancarlo, Leocani, Letizia

“…Background: Neuroretinal atrophy is associated with whole-brain atrophy and disease activity in multiple sclerosis (MS). Recent findings support that…”
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dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice by Colasante, Gaia, Lignani, Gabriele, Brusco, Simone, Di Berardino, Claudia, Carpenter, Jenna, Giannelli, Serena, Valassina, Nicholas, Bido, Simone, Ricci, Raffaele, Castoldi, Valerio, Marenna, Silvia, Church, Timothy, Massimino, Luca, Morabito, Giuseppe, Benfenati, Fabio, Schorge, Stephanie, Leocani, Letizia, Kullmann, Dimitri M., Broccoli, Vania

“…Dravet syndrome (DS) is a severe epileptic encephalopathy caused mainly by heterozygous loss-of-function mutations of the SCN1A gene, indicating…”
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Cas9/sgRNA selective targeting of the P23H Rhodopsin mutant allele for treating retinitis pigmentosa by intravitreal AAV9.PHP.B-based delivery by Giannelli, Serena G, Luoni, Mirko, Castoldi, Valerio, Massimino, Luca, Cabassi, Tommaso, Angeloni, Debora, Demontis, Gian Carlo, Leocani, Letizia, Andreazzoli, Massimiliano, Broccoli, Vania

“…Abstract P23H is the most common mutation in the RHODOPSIN (RHO) gene leading to a dominant form of retinitis pigmentosa (RP), a rod photoreceptor degeneration…”
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Optical Coherence Tomography and Visual Evoked Potentials as Prognostic and Monitoring Tools in Progressive Multiple Sclerosis by Guerrieri, Simone, Comi, Giancarlo, Leocani, Letizia

“…Understanding the mechanisms underlying progression and developing new treatments for progressive multiple sclerosis (PMS) are among the major challenges in…”
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Stroke and digital technology: a wake-up call from COVID-19 pandemic by Iodice, Francesco, Romoli, Michele, Giometto, Bruno, Clerico, Marinella, Tedeschi, Gioacchino, Bonavita, Simona, Leocani, Letizia, Lavorgna, Luigi

“…Introduction The pandemic has implemented the need for new digital technologies as useful tools during the emergency and the long recovery phase that will…”
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Using Smartphones and Wearable Devices to Monitor Behavioral Changes During COVID-19 by Sun, Shaoxiong, Folarin, Amos A, Ranjan, Yatharth, Rashid, Zulqarnain, Conde, Pauline, Stewart, Callum, Cummins, Nicholas, Matcham, Faith, Dalla Costa, Gloria, Simblett, Sara, Leocani, Letizia, Lamers, Femke, Sørensen, Per Soelberg, Buron, Mathias, Zabalza, Ana, Guerrero Pérez, Ana Isabel, Penninx, Brenda Wjh, Siddi, Sara, Haro, Josep Maria, Myin-Germeys, Inez, Rintala, Aki, Wykes, Til, Narayan, Vaibhav A, Comi, Giancarlo, Hotopf, Matthew, Dobson, Richard Jb

“…In the absence of a vaccine or effective treatment for COVID-19, countries have adopted nonpharmaceutical interventions (NPIs) such as social distancing and…”
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Fifteen Years of Wireless Sensors for Balance Assessment in Neurological Disorders by Zampogna, Alessandro, Mileti, Ilaria, Palermo, Eduardo, Celletti, Claudia, Paoloni, Marco, Manoni, Alessandro, Mazzetta, Ivan, Dalla Costa, Gloria, Pérez-López, Carlos, Camerota, Filippo, Leocani, Letizia, Cabestany, Joan, Irrera, Fernanda, Suppa, Antonio

“…Balance impairment is a major mechanism behind falling along with environmental hazards. Under physiological conditions, ageing leads to a progressive decline…”
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Assessing disability and relapses in multiple sclerosis on tele-neurology by Moccia, Marcello, Lanzillo, Roberta, Brescia Morra, Vincenzo, Bonavita, Simona, Tedeschi, Gioacchino, Leocani, Letizia, Lavorgna, Luigi

“…Background As a consequence of the coronavirus disease 2019 (COVID-19) pandemic, a large amount of consultations will be delivered through tele-medicine,…”
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AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy by Morabito, Giuseppe, Giannelli, Serena G., Ordazzo, Gabriele, Bido, Simone, Castoldi, Valerio, Indrigo, Marzia, Cabassi, Tommaso, Cattaneo, Stefano, Luoni, Mirko, Cancellieri, Cinzia, Sessa, Alessandro, Bacigaluppi, Marco, Taverna, Stefano, Leocani, Letizia, Lanciego, José L., Broccoli, Vania

“…The lack of technology for direct global-scale targeting of the adult mouse nervous system has hindered research on brain processing and dysfunctions…”
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In vivo structural and functional assessment of optic nerve damage in neuromyelitis optica spectrum disorders and multiple sclerosis by Vabanesi, Marco, Pisa, Marco, Guerrieri, Simone, Moiola, Lucia, Radaelli, Marta, Medaglini, Stefania, Martinelli, Vittorio, Comi, Giancarlo, Leocani, Letizia

“…Early detection of neuromyelitis optica spectrum disorders (NMOSD), especially after optic neuritis, a presenting manifestation commonly observed also in…”
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e-Health and multiple sclerosis: An update by Lavorgna, Luigi, Brigo, Francesco, Moccia, Marcello, Leocani, Letizia, Lanzillo, Roberta, Clerico, Marinella, Abbadessa, Gianmarco, Schmierer, Klaus, Solaro, Claudio, Prosperini, Luca, Tedeschi, Gioacchino, Giovannoni, Gavin, Bonavita, Simona

“…e-Health (or digital healthcare) is becoming increasingly relevant in multiple sclerosis (MS) clinical management. We aim to review and discuss current status…”
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Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions by Magri, Laura, Cambiaghi, Marco, Cominelli, Manuela, Alfaro-Cervello, Clara, Cursi, Marco, Pala, Mauro, Bulfone, Alessandro, Garcìa-Verdugo, Jose Manuel, Leocani, Letizia, Minicucci, Fabio, Poliani, Pietro Luigi, Galli, Rossella

“…Tuberous Sclerosis Complex (TSC) is a multisystem genetic disorder characterized by hamartomatous neurological lesions that exhibit abnormal cell proliferation…”
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The hypometabolic state: a good predictor of a better prognosis in amyotrophic lateral sclerosis by Cattaneo, Marina, Jesus, Pierre, Lizio, Andrea, Fayemendy, Philippe, Guanziroli, Nicoletta, Corradi, Ettore, Sansone, Valeria, Leocani, Letizia, Filippi, Massimo, Riva, Nilo, Corcia, Philippe, Couratier, Philippe, Lunetta, Christian

“…BackgroundMalnutrition and weight loss are negative prognostic factors for survival in patients with amyotrophic lateral sclerosis (ALS). However, energy…”
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Training in the practice of noninvasive brain stimulation: Recommendations from an IFCN committee by Fried, Peter J., Santarnecchi, Emiliano, Antal, Andrea, Bartres-Faz, David, Bestmann, Sven, Carpenter, Linda L., Celnik, Pablo, Edwards, Dylan, Farzan, Faranak, Fecteau, Shirley, George, Mark S., He, Bin, Kim, Yun-Hee, Leocani, Letizia, Lisanby, Sarah H., Loo, Colleen, Luber, Bruce, Nitsche, Michael A., Paulus, Walter, Rossi, Simone, Rossini, Paolo M., Rothwell, John, Sack, Alexander T., Thut, Gregor, Ugawa, Yoshikazu, Ziemann, Ulf, Hallett, Mark, Pascual-Leone, Alvaro

“…•The field of NIBS is expanding and adequate training for all NIBS practitioners is needed.•Training should be matched to the responsibilities of Technicians,…”
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Serum phosphorylated neurofilament heavy-chain levels reflect phenotypic heterogeneity and are an independent predictor of survival in motor neuron disease by Falzone, Yuri Matteo, Domi, Teuta, Agosta, Federica, Pozzi, Laura, Schito, Paride, Fazio, Raffaella, Del Carro, Ubaldo, Barbieri, Alessandra, Comola, Mauro, Leocani, Letizia, Comi, Giancarlo, Carrera, Paola, Filippi, Massimo, Quattrini, Angelo, Riva, Nilo

“…To investigate the prognostic role and the major determinants of serum phosphorylated neurofilament heavy -chain (pNfH) concentration across a large cohort of…”
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