Search Results - "Letendre, Scott L"

Time of Day Influences Concentrations of Total Protein and Albumin in Cerebrospinal Fluid in HIV by Kakarla, Visesha, Letendre, Scott L, Ellis, Ronald J

“…The accumulation of soluble proteins and metabolites during wakefulness and their clearance during sleep via the glymphatic system occurs in healthy adults and…”
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Increased Intrathecal Immune Activation in Virally Suppressed HIV-1 Infected Patients with Neurocognitive Impairment by Edén, Arvid, Marcotte, Thomas D, Heaton, Robert K, Nilsson, Staffan, Zetterberg, Henrik, Fuchs, Dietmar, Franklin, Donald, Price, Richard W, Grant, Igor, Letendre, Scott L, Gisslén, Magnus

“…Although milder forms of HIV-associated neurocognitive disorder (HAND) remain prevalent, a correlation to neuronal injury has not been established in patients…”
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The identification of intact HIV proviral DNA from human cerebrospinal fluid by Zhang, Zhan, Reece, Monica D., Roa, Sebastian, Tyor, William, Franklin, Donald R., Letendre, Scott L., Marconi, Vincent C., Anderson, Albert M., Gavegnano, Christina

“…We evaluated the HIV-1 DNA reservoir in peripheral blood mononuclear cells (PBMC) and cerebrospinal fluid (CSF) in people with HIV (PWH) and associations to…”
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Elevated Biomarkers of Inflammation and Vascular Dysfunction Are Associated with Distal Sensory Polyneuropathy in People with HIV by Andalibi, Mohammadsobhan Sheikh, Fields, Jerel Adam, Iudicello, Jennifer E, Diaz, Monica M, Tang, Bin, Letendre, Scott L, Ellis, Ronald J

“…Distal sensory polyneuropathy (DSP) is a disabling, chronic condition in people with HIV (PWH), even those with viral suppression of antiretroviral therapy…”
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Associations between Cognition, Gender and Monocyte Activation among HIV Infected Individuals in Nigeria by Royal, 3rd, Walter, Cherner, Mariana, Burdo, Tricia H, Umlauf, Anya, Letendre, Scott L, Jumare, Jibreel, Abimiku, Alash'le, Alabi, Peter, Alkali, Nura, Bwala, Sunday, Okwuasaba, Kanayo, Eyzaguirre, Lindsay M, Akolo, Christopher, Guo, Ming, Williams, Kenneth C, Blattner, William A

“…The potential role of gender in the occurrence of HIV-related neurocognitive impairment (NCI) and associations with markers of HIV-related immune activity has…”
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Cannabis use may attenuate neurocognitive performance deficits resulting from methamphetamine use disorder by Rogers, Jeffrey M, Grant, Igor, Marcondes, Maria Cecilia G, Morgan, Erin E, Cherner, Mariana, Ellis, Ronald J, Letendre, Scott L, Heaton, Robert K, Iudicello, Jennifer E

“…Methamphetamine and cannabis are two widely used, and frequently co-used, substances with possibly opposing effects on the central nervous system. Evidence of…”
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Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations by Oliveira, Michelli F, Chaillon, Antoine, Nakazawa, Masato, Vargas, Milenka, Letendre, Scott L, Strain, Matthew C, Ellis, Ronald J, Morris, Sheldon, Little, Susan J, Smith, Davey M, Gianella, Sara

“…Even when antiretroviral therapy (ART) is started early after infection, HIV DNA might persist in the central nervous system (CNS), possibly contributing to…”
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Switching to Tenofovir Alafenamide in Elvitegravir-Based Regimens: Pharmacokinetics and Antiviral Activity in Cerebrospinal Fluid by Ma, Qing, Ocque, Andrew J, Morse, Gene D, Sanders, Chelsea, Burgi, Alina, Little, Susan J, Letendre, Scott L

“…Abstract Background Tenofovir alafenamide fumarate (TAF) co-formulated with elvitegravir (EVG; E), cobicistat (C), and emtricitabine (F), a recommended…”
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Beyond the Syndemic of Opioid Use Disorders and HIV: The Impact of Opioids on Viral Reservoirs by Trunfio, Mattia, Chaillon, Antoine, Beliakova-Bethell, Nadejda, Deiss, Robert, Letendre, Scott L, Riggs, Patricia K, Higgins, Niamh, Gianella, Sara

“…People with HIV are more likely to have opioid use disorder and to be prescribed opioids for chronic pain than the general population; however, the effects of…”
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Increasing Neuroinflammation Relates to Increasing Neurodegeneration in People with HIV by Tavasoli, Azin, Gelman, Benjamin B, Marra, Christina M, Clifford, David B, Iudicello, Jennifer E, Rubin, Leah H, Letendre, Scott L, Tang, Bin, Ellis, Ronald J

“…HIV infection causes neuroinflammation and immune activation (NIIA) and systemic inflammation and immune activation (SIIA), which in turn drive…”
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Effects of Opioid Withdrawal on Psychobiology in People Living with HIV by Grant, Igor, Krupitsky, Evgeny, Vetrova, Marina, Umlauf, Anya, Heaton, Robert K, Hauger, Richard L, Toussova, Olga, Franklin, Donald R, Letendre, Scott L, Woody, George, Blokhina, Elena, Lioznov, Dmitry, Zvartau, Edwin

“…Many persons with opioid use disorders (OUDs) have HIV disease and experience clinically significant stress after they enroll in abstinence-based treatment and…”
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The Combined Effects of Cannabis, Methamphetamine, and HIV on Neurocognition by Rogers, Jeffrey M, Iudicello, Jennifer E, Marcondes, Maria Cecilia G, Morgan, Erin E, Cherner, Mariana, Ellis, Ronald J, Letendre, Scott L, Heaton, Robert K, Grant, Igor

“…Methamphetamine and cannabis are two widely used substances among people living with HIV (PLWH). Whereas methamphetamine use has been found to worsen…”
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Reply to Augello, P.A.; Wu, J. Comment on "Rogers et al. The Combined Effects of Cannabis, Methamphetamine, and HIV on Neurocognition. Viruses 2023, 15 , 674" by Rogers, Jeffrey M, Iudicello, Jennifer E, Marcondes, Maria Cecilia G, Morgan, Erin E, Cherner, Mariana, Ellis, Ronald J, Letendre, Scott L, Heaton, Robert K, Grant, Igor

“…We thank Augello and Wu [...]…”
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Elevated Plasma Protein Carbonyl Concentration Is Associated with More Abnormal White Matter in People with HIV by Riggs, Patricia K, Anderson, Albert M, Tang, Bin, Rubin, Leah H, Morgello, Susan, Marra, Christina M, Gelman, Benjamin B, Clifford, David B, Franklin, Donald, Heaton, Robert K, Ellis, Ronald J, Fennema-Notestine, Christine, Letendre, Scott L

“…Structural brain abnormalities, including those in white matter (WM), remain common in people with HIV (PWH). Their pathogenesis is uncertain and may reflect…”
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Current Challenges and Solutions for Clinical Management and Care of People with HIV: Findings from the 12th Annual International HIV and Aging Workshop by Yu, Xiaoying, Lobo, Judith D, Sundermann, Erin, Baker, Darren J, Tracy, Russell P, Kuchel, George A, Stephenson, Kathryn E, Letendre, Scott L, Brew, Bruce, Cysique, Lucette A, Dale, Sannisha K, Wallen, Chelsie, Kunisaki, Ken M, Guaraldi, Giovanni, Milic, Jovana, Winston, Alan, Moore, David J, Margolick, Joseph B, Erlandson, Kristine M

“…People with HIV on combination antiretroviral therapy (ART) have longer life expectancy and are increasingly experiencing age-related comorbidities. Thus,…”
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Cannabis Use and Cannabidiol Modulate HIV-Induced Alterations in TREM2 Expression: Implications for Age-Related Neuropathogenesis by Avalos, Bryant, Kulbe, Jacqueline R, Ford, Mary K, Laird, Anna Elizabeth, Walter, Kyle, Mante, Michael, Florio, Jazmin B, Boustani, Ali, Chaillon, Antoine, Schlachetzki, Johannes C M, Sundermann, Erin E, Volsky, David J, Rissman, Robert A, Ellis, Ronald J, Letendre, Scott L, Iudicello, Jennifer, Fields, Jerel Adam

“…Triggering receptor expressed on myeloid cells 2 (TREM2) is involved in neuroinflammation and HIV-associated neurocognitive impairment (NCI). People with HIV…”
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A Haptoglobin Exon Copy Number Variant Associates With HIV-Associated Neurocognitive Impairment in European and African-Descent Populations by Bai, Haimeng, Kaur, Harpreet, Kallianpur, Asha R, Hulgan, Todd, Franklin, Jr, Donald R, Letendre, Scott L, Ellis, Ronald J, Bush, William S

“…A common two-exon deletion distinguishes the gene encoding the free hemoglobin capturing protein-haptoglobin (HP)-into two alleles: and . To evaluate the…”
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Plasma biomarkers of vascular dysfunction uniquely relate to a vascular-risk profile of neurocognitive deficits in virally-suppressed adults with HIV by Saloner, Rowan, Sun-Suslow, Ni, Morgan, Erin E., Lobo, Judith, Cherner, Mariana, Ellis, Ronald J., Heaton, Robert K., Grant, Igor, Letendre, Scott L., Iudicello, Jennifer E.

“…Chronic inflammation and vascular dysfunction (e.g., chronic endothelial activation) are related yet dissociable mechanisms of HIV-associated neurocognitive…”
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Identification of an abbreviated test battery for detection of HIV-associated neurocognitive impairment in an early-managed HIV-infected cohort by Moore, David J, Roediger, Mollie J P, Eberly, Lynn E, Blackstone, Kaitlin, Hale, Braden, Weintrob, Amy, Ganesan, Anuradha, Agan, Brian K, Letendre, Scott L, Crum-Cianflone, Nancy F

“…HIV-associated neurocognitive disorders (HAND) remain prevalent despite improved antiretroviral treatment (ART), and it is essential to have a sensitive and…”
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Cross-sectional characterization of HIV-1 env compartmentalization in cerebrospinal fluid over the full disease course by HARRINGTON, Patrick R, SCHNELL, Gretja, PRICE, Richard W, SWANSTROM, Ronald, LETENDRE, Scott L, RITOLA, Kimberly, ROBERTSON, Kevin, HALL, Colin, BURCH, Christina L, JABARA, Cassandra B, MOORE, Dominic T, ELLIS, Ronald J

“…To characterize HIV-1 env compartmentalization between cerebrospinal fluid (CSF) and peripheral blood plasma over all stages of the HIV-1 disease course, and…”
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