Search Results - "Letícia Maria Castro"

NF-κB Signaling Pathway Inhibitors as Anticancer Drug Candidates by de Castro Barbosa, Maria Letícia, da Conceicao, Raissa Alves, Fraga, Aline Guerra Manssour, Camarinha, Barbara Dias, de Carvalho Silva, Gabriela Cristina, Lima, Antonio Gilcler Ferreira, Cardoso, Elisama Azevedo, de Oliveira Freitas Lione, Viviane

“…Cancer incidence represents an important public health problem worldwide. Nuclear factor kappa B (NF- κB) transcription factor plays a pivotal role in the…”
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Synthesis and pharmacological evaluation of novel phenyl sulfonamide derivatives designed as modulators of pulmonary inflammatory response by Barbosa, Maria Letícia de Castro, Ramos, Thiago José Figueira, de Arantes, Ana Carolina Santos, Martins, Marco Aurélio, Silva, Patrícia Machado Rodrigues E, Barreiro, Eliezer J, Lima, Lídia Moreira

“…In this paper we report the design, synthesis and pharmacological evaluation of a new series of phenyl sulfonamide derivatives 2a-h and 3-8 planned by…”
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Synthesis and pharmacological evaluation of pyrazine N-acylhydrazone derivatives designed as novel analgesic and anti-inflammatory drug candidates by Silva, Yolanda Karla Cupertino da, Augusto, Cristina Villarinho, Barbosa, Maria Letícia de Castro, Melo, Gabriela Muniz de Albuquerque, Queiroz, Aline Cavalcanti de, Dias, Thays de Lima Matos Freire, Júnior, Walfrido Bispo, Barreiro, Eliezer J., Lima, Lídia Moreira, Alexandre-Moreira, Magna Suzana

“…In this paper, we report the design, synthesis and pharmacological evaluation of a series of pyrazine N-acylhydrazone (NAH) derivatives (2a–s), planned by…”
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Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors by Barbosa, Maria Letícia de Castro, Lima, Lídia Moreira, Tesch, Roberta, Sant'Anna, Carlos Mauricio R., Totzke, Frank, Kubbutat, Michael H.G., Schächtele, Christoph, Laufer, Stefan A., Barreiro, Eliezer J.

“…Novel 2-chloro-4-anilino-quinazolines designed as EGFR and VEGFR-2 dual inhibitors were synthesized and evaluated for inhibitory effects. EGFR and VEGFR-2 are…”
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Therapeutic approaches for tumor necrosis factor inhibition by Barbosa, Maria Letícia de Castro, Fumian, Milla Machado, Miranda, Ana Luísa Palhares de, Barreiro, Eliezer J., Lima, Lídia Moreira

“…Tumor necrosis factor (TNF) consists of an inflammatory cytokine essential for homeostasis and organism defense. Despite its physiological relevance, both…”
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Synthesis and pharmacological evaluation of N-phenyl-acetamide sulfonamides designed as novel non-hepatotoxic analgesic candidates by de Castro Barbosa, Maria Letícia, de Albuquerque Melo, Gabriela Muniz, da Silva, Yolanda Karla Cupertino, de Oliveira Lopes, Raquel, de Souza, Everton Tenório, de Queiroz, Aline Cavalcanti, Smaniotto, Salete, Alexandre-Moreira, Magna Suzana, Barreiro, Eliezer J., Lima, Lídia Moreira

“…In this paper we report the design, synthesis and pharmacological evaluation of a series of N-phenyl-acetamide sulfonamide derivatives ( 5a– g), planned by…”
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Production and morphological characteristics of Tanzania grass under different grazing heights by Rondineli Pavezzi Barbero, Marco Aurélio Alves de Freitas Barbosa, Letícia Maria de Castro, Edson Luis de Azambuja Ribeiro, Ivone Yurika Mizubuti, Valter Harry Bumbieris Júnior, Leandro das Dores Ferreira da Silva

“…The objective of this study was to determine the best height of the Tanzania grass under grazing, assessing morphological and productive characteristics of the…”
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SUPLEMENTAÇÃO COM FONTES PROTEICAS NA TERMINAÇÃO DE NOVILHAS DE CORTE: ESTUDO BIOECONÔMICO by Barbero, Rondineli Pavezzi, Barbosa, Marco Aurélio Alves de Freitas, Fortaleza, Ana Paula de Souza, Massaro Júnior, Fernando Luiz, Silva, Leandro das Dores Ferreira da, Castro, Letícia Maria de

“…Resumo O objetivo deste trabalho foi avaliar biológica e economicamente a utilização de três fontes proteicas (farelo de soja (FS), caroço de algodão (CA) ou…”
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High Dose Ascorbate Causes Both Genotoxic and Metabolic Stress in Glioma Cells by Castro, Maria Leticia, Carson, Georgia M, McConnell, Melanie J, Herst, Patries M

“…We have previously shown that exposure to high dose ascorbate causes double stranded breaks (DSBs) and a build-up in S-phase in glioblastoma (GBM) cell lines…”
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Synthesis, in silico, and in vitro evaluation of 7-chloro-quinolines designed as myeloperoxidase inhibitors by Pereira, Gabriel Rodrigues Coutinho, Fraga, Letícia de Souza, de Jesus, Romulo Pereira, Queiroz, Rafael Compan, Leite, Beatriz de Frias, Alves, Marina Amaral, de Mesquita, Joelma Freire, de Souza, Alessandra Mendonça Teles, da Silva, Leandro Louback, Rodrigues, Carlos Rangel, Cabral, Lucio Mendes, Abrahim-Vieira, Barbara de Azevedo, Barbosa, Maria Leticia de Castro

“…•Synthesis, in silico & in vitro evaluation of 7‑chloro-quinolines as MPO inhibitors.•Derivatives 13k, 13l, and 14 emerged as the most potent MPO…”
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Brazilian national production of active pharmaceutical ingredients: regulatory and strategic framework by Tonini, Marlon Daniel L, Lopes, Raquel O, Barbosa, Maria Letícia C

“…Active Pharmaceutical Ingredient (API) is any component of the final pharmaceutical product that serves as the active ingredient. The goal of the API…”
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Performance of beef cattle on pasture of Brachiaria brizantha cv. Xaraés maintained at different sward heights by Marco Aurélio Alves de Freitas Barbosa, Letícia Maria Castro, Rondineli Pavezzi Barbero, Vinicius Campachi Brito, Renan Lucas Miorin, Leandro das Dores Ferreira da Silva, Edson Luis de Azambuja Ribeiro, Ivone Yurika Mizubuti

“…The production of grazing cattle has been very interesting, due to the low cost to produce fodder, compared to other sources of forage used to feed these…”
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Forage production and structural composition of pastures of Xaraés grass managed in different grazing heights by Letícia Maria Castro, Marco Aurélio Alves de Freitas Barbosa, Rondineli Pavezzi Barbero, Vinicius Campachi Brito, Rafael Mantegazza Saad, Edson Luis de Azambuja Ribeiro, Ivone Yurika Mizubuti, Ana Maria Bridi

“…The objective of this study was to analyze the production of dry mass, forage accumulation rate and the structural composition of Brachiaria brizantha cv…”
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Sodium-glucose cotransporter 2 (SGLT-2) inhibitors: a new antidiabetic drug class by da Silva, Paula Nogueira, da Conceição, Raissa Alves, do Couto Maia, Rodolfo, de Castro Barbosa, Maria Leticia

“…Diabetes mellitus is a chronic, complex and multifactorial disease associated characteristically with hyperglycemia. One of the most recently approved…”
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Ingestive behavior of cattle kept in Brachiaria brizantha cv. Xaraés grass managed under different grazing heights by Marco Aurélio Alves de Freitas Barbosa, Letícia Maria Castro, Rondineli Pavezzi Barbero, Vinicius Campachi Brito, Renan Lucas Miorin, Rafael Mantegazza Saad, Edson Luis de Azambuja Ribeiro, Valter Harry Bumbieris Junior

“…This experiment was conducted to evaluate the effect of grazing heights on daytime behavioral activities of Nellore beef cattle in the rainy season. The…”
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SUPLEMENTAÇÃO COM FONTES PROTEICAS NA TERMINAÇÃO DE NOVILHAS DE CORTE: ESTUDO BIOECONÔMICO by Barbero, Rondineli Pavezzi, Barbosa, Marco Aurélio Alves de Freitas, Fortaleza, Ana Paula de Souza, Massaro Júnior, Fernando Luiz, Silva, Leandro das Dores Ferreira da, Castro, Letícia Maria de

“…Resumo O objetivo deste trabalho foi avaliar biológica e economicamente a utilização de três fontes proteicas (farelo de soja (FS), caroço de algodão (CA) ou…”
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Características produtivas e morfológicas do capim Tanzânia em diferentes intensidades de pastejo by Barbero, Rondineli Pavezzi, Barbosa, Marco Aurélio Alves de Freitas, Castro, Letícia Maria de, Ribeiro, Edson Luis De Azambuja, Mizubuti, Ivone Yurika, Bumbieris Júnior, Valter Harry, Silva, Leandro das Dores Ferreira da

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Produção de forragem e composição estrutural de pastos de Brachiaria brizantha cv. Xaraés manejados em diferentes alturas de pastejo by Castro, Letícia Maria, Barbosa, Marco Aurélio Alves de Freitas, Barbero, Rondineli Pavezzi, Brito, Vinicius Campachi, Saad, Rafael Mantegazza, Ribeiro, Edson Luis de Azambuja, Mizubuti, Ivone Yurika, Bridi, Ana Maria

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Desempenho de bovinos de corte em pastos de Brachiaria brizantha cv. Xaraés manejados em diferentes alturas de pastejo by Barbosa, Marco Aurélio Alves de Freitas, Castro, Letícia Maria, Barbero, Rondineli Pavezzi, Brito, Vinicius Campachi, Miorin, Renan Lucas, Silva, Leandro Das Dores Ferreira da, Ribeiro, Edson Luis de Azambuja, Mizubuti, Ivone Yurika

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SUPPLEMENTATION WITH PROTEIN SOURCES IN THE FINISHING STAGE OF BEEF HEIFERS: A BIOECONOMICAL STUDY by Rondineli Pavezzi Barbero, Marco Aurélio Alves de Freitas Barbosa, Ana Paula de Souza Fortaleza, Fernando Luiz Massaro Júnior, Leandro das Dores Ferreira da Silva, Letícia Maria de Castro

“…The purpose of this study was to evaluate biological and economically the use of three protein sources (soybean meal (SM), cottonseed (CS) or turnip cake…”
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