Search Results - "Lesser, David R."
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The Energetic Basis of Specificity in the Eco RI Endonuclease-DNA Interaction
Published in Science (American Association for the Advancement of Science) (09-11-1990)“…High sequence selectivity in DNA-protein interactions was analyzed by measuring discrimination by Eco RI endonuclease between the recognition site GAATTC and…”
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Facilitated Distortion of the DNA Site Enhances EcoRI Endonuclease-DNA Recognition
Published in Proceedings of the National Academy of Sciences - PNAS (15-08-1993)“…We have measured the binding of EcoRI endonuclease to a complete set of purine-base analogue sites, each of which deletes one functional group that forms a…”
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Loss of THCCOOH from Urine Specimens Stored in Polypropylene and Polyethylene Containers at Different Temperatures
Published in Journal of analytical toxicology (01-10-2000)“…The loss of Δ9-tetrahydrocannabinol (THCCOOH) from urine specimens stored in polypropylene and polyethylene containers at 4°C and 25°C was examined. All…”
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Structural adaptations in the interaction of EcoRI endonuclease with methylated GAATTC sites
Published in The EMBO journal (03-06-1996)“…We have studied the interaction of EcoRI endonuclease with oligonucleotides containing GAATTC sites bearing one or two adenine‐N6‐methyl groups, which would be…”
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Stereoselective interaction with chiral phosphorothioates at the central DNA kink of the EcoRI endonuclease-GAATTC complex
Published in The Journal of biological chemistry (05-12-1992)“…We have probed the contacts between EcoRI endonuclease and the central phosphate of its recognition site GAApTTC, using synthetic oligonucleotides containing…”
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