Search Results - "Lessard, Michel"

Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) by Akasaka, Takashi, Balasas, Theodore, Russell, Lisa J., Sugimoto, Kei-ji, Majid, Aneela, Walewska, Renata, Karran, E. Loraine, Brown, David G., Cain, Kelvin, Harder, Lana, Gesk, Stefan, Martin-Subero, Jose Ignacio, Atherton, Mark G., Brüggemann, Monika, Calasanz, María José, Davies, Teresa, Haas, Oskar A., Hagemeijer, Anne, Kempski, Helena, Lessard, Michel, Lillington, Debra M., Moore, Sarah, Nguyen-Khac, Florence, Radford-Weiss, Isabelle, Schoch, Claudia, Struski, Stéphanie, Talley, Polly, Welham, Melanie J., Worley, Helen, Strefford, Jon C., Harrison, Christine J., Siebert, Reiner, Dyer, Martin J.S.

“…CCAAT enhancer-binding protein (CEBP) transcription factors play pivotal roles in proliferation and differentiation, including suppression of myeloid…”
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Identification of Distinct Molecular Phenotypes in Acute Megakaryoblastic Leukemia by Gene Expression Profiling by Bourquin, Jean-Pierre, Subramanian, Aravind, Langebrake, Claudia, Reinhardt, Dirk, Bernard, Olivier, Ballerini, Paola, Baruchel, André, Cavé, Hélène, Dastugue, Nicole, Hasle, Henrik, Kaspers, Gertjan L., Lessard, Michel, Michaux, Lucienne, Vyas, Paresh, van Wering, Elisabeth, Zwaan, Christian M., Golub, Todd R., Orkin, Stuart H.

“…Individuals with Down syndrome (DS) are predisposed to develop acute megakaryoblastic leukemia (AMKL), characterized by expression of truncated GATA1…”
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Non-traumatic hypertrophic callus of the fibula mimicking osteosarcoma in osteogenesis imperfecta type V: a case report by Radu, Arnold, Kanza, Rene Epunza, Barabas, Dezso, Lessard, Michel, Berube, Michel

“…We report a case of hyperplastic callus mimicking osteosarcoma in the fibula of a patient with osteogenesis imperfecta type V. Among the various imaging…”
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ETV6-NCOA2: A Novel Fusion Gene in Acute Leukemia Associated with Coexpression of T-Lymphoid and Myeloid Markers and Frequent NOTCH1 Mutations by STREHL, Sabine, NEBRAL, Karin, HAAS, Oskar A, IZRAELI, Shai, KÖNIG, Margit, HARBOTT, Jochen, STROBL, Herbert, RATEI, Richard, STRUSKI, Stephanie, BIELORAI, Bella, LESSARD, Michel, ZIMMERMANN, Martin

“…Purpose: The ETV6 gene has been reported to be fused to a multitude of partner genes in various hematologic malignancies with 12p13 aberrations. Cytogenetic…”
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Endotoxin-induced heart dysfunction in rats: Assessment of myocardial perfusion and permeability and the role of fluid resuscitation by Chagnon, Frederic, Bentourkia, M’hamed, Lecomte, Roger, Lessard, Michel, Lesur, Olivier

“…OBJECTIVE:The pathophysiology of sepsis-induced myocardial dysfunction is still controversial. Whether microcirculatory hypoperfusion together with capillary…”
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ETV6/GOT1 fusion in a case of t(10;12)(q24;p13)-positive myelodysplastic syndrome by Struski, Stephanie, Mauvieux, Laurent, Gervais, Carine, Helias, Catherine, Liu, Kun Lun, Lessard, Michel

“…1 Laboratoire d’Hématologie, Hôpital de Hautepierre, Avenue Molière, Strasbourg 2 Département d’Hématologie et d’Oncologie, Hôpital de Hautepierre, Strasbourg,…”
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A TEL-JAK2 Fusion Protein with Constitutive Kinase Activity in Human Leukemia by Lacronique, Virginie, Boureux, Anthony, Della Valle, Véronique, Poirel, Helene, Quang, Christine Tran, Mauchauffé, Martine, Berthou, Christian, Lessard, Michel, Berger, Roland, Ghysdael, Jacques, Bernard, Olivier A.

“…The Janus family of tyrosine kinases (JAK) plays an essential role in development and in coupling cytokine receptors to downstream intracellular signaling…”
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Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the European Working Party by Grimwade, David, Biondi, Andrea, Mozziconacci, Marie-Joëlle, Hagemeijer, Anne, Berger, Roland, Neat, Michael, Howe, Kathy, Dastugue, Nicole, Jansen, Joop, Radford-Weiss, Isabelle, Coco, Francesco Lo, Lessard, Michel, Hernandez, Jesus-Maria, Delabesse, Eric, Head, David, Liso, Vincenzo, Sainty, Danielle, Flandrin, Georges, Solomon, Ellen, Birg, Françoise, Lafage-Pochitaloff, Marina

“…Acute promyelocytic leukemia (APL) is typified by the t(15;17), generating the PML-RARα fusion and predicting a beneficial response to retinoids. However, a…”
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Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951 by Cavé, Hélène, Suciu, Stefan, Preudhomme, Claude, Poppe, Bruce, Robert, Alain, Uyttebroeck, Anne, Malet, Michèle, Boutard, Patrick, Benoit, Yves, Mauvieux, Laurent, Lutz, Patrick, Méchinaud, Françoise, Grardel, Nathalie, Mazingue, Françoise, Dupont, Madeleine, Margueritte, Geneviève, Pages, Marie-Pierre, Bertrand, Yves, Plouvier, Emmanuel, Brunie, Ghislaine, Bastard, Christian, Plantaz, Dominique, Velde, Isabel Vande, Hagemeijer, Anne, Speleman, Frank, Lessard, Michel, Otten, Jacques, Vilmer, Etienne, Dastugue, Nicole

“…In a series of 153 children with T-cell malignancies enrolled in 2 consecutive European Organization for Research and Treatment of Cancer (EORTC) trials, we…”
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Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia by Chapiro, Elise, Russell, Lisa, Radford-Weiss, Isabelle, Bastard, Christian, Lessard, Michel, Struski, Stephanie, Cave, Helene, Fert-Ferrer, Sandra, Barin, Carole, Maarek, Odile, Della-Valle, Veronique, Strefford, Jonathan C., Berger, Roland, Harrison, Christine J., Bernard, Olivier A., Nguyen-Khac, Florence, the Groupe Francophone de Cytogénétique Hématologique

“…Subtle variation in the expression or function of a small group of transcription factors can drive leukemogenesis. The CEBPA protein is known to regulate the…”
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HOX11L2/TLX3 is transcriptionally activated through T-cell regulatory elements downstream of BCL11B as a result of the t(5;14)(q35;q32) by Su, Xin-Ying, Della-Valle, Véronique, Andre-Schmutz, Isabelle, Lemercier, Claudie, Radford-Weiss, Isabelle, Ballerini, Paola, Lessard, Michel, Lafage-Pochitaloff, Marina, Mugneret, Francine, Berger, Roland, Romana, Serge P., Bernard, Olivier A., Penard-Lacronique, Virginie

“…The t(5;14)(q35;q32) chromosomal translocation is specifically observed in up to 20% of childhood T-cell acute lymphoblastic leukemia (T-ALL). It affects the…”
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Cytogenetic profile of childhood and adult megakaryoblastic leukemia (M7): a study of the Groupe Français de Cytogénétique Hématologique (GFCH) by Dastugue, Nicole, Lafage-Pochitaloff, Marina, Pagès, Marie-Pierre, Radford, Isabelle, Bastard, Christian, Talmant, Pascaline, Mozziconacci, Marie Joelle, Léonard, Claude, Bilhou-Nabéra, Christelle, Cabrol, Christine, Capodano, Anne-Marie, Cornillet-Lefebvre, Pascale, Lessard, Michel, Mugneret, Francine, Pérot, Christine, Taviaux, Sylvie, Fenneteaux, Odile, Duchayne, Eliane, Berger, Roland

“…To draw the cytogenetic profile of childhood and adult acute megakaryoblastic leukemia (M7), the Groupe Français de Cytogénétique Hématologique collected 53…”
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ETV6/GOT1 fusion in a case of t(10;12)(q24;p13)-positive myelodysplastic syndrome. Authors' Reply by STRUSKI, Stephanie, MAUVIEUX, Laurent, CERVAIS, Carine, HELIAS, Catherine, KUN LUN LIU, LESSARD, Michel

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Effect of section width and casting rate on variations of formwork pressure of self-consolidating concrete by KHAYAT, K, ASSAAD, J, MESBAH, H, LESSARD, M

“…The influence of formwork dimensions and rate of casting of self-consolidating concrete (SCC) on the development and variations of lateral pressure were…”
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Circulating cell-derived microparticles in Crohn's disease by CHAMOUARD, Patrick, DESPREZ, Dominique, HUGEL, Bénédicte, KUNZELMANN, Corinne, GIDON-JEANGIRARD, Carole, LESSARD, Michel, BAUMANN, René, FREYSSINET, Jean-Marie, GRUNEBAUM, Lélia

“…Procoagulant membrane microparticles can be released from activated or apoptotic cells in response to various environmental stimuli. The aim of this study was…”
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A new translocation t(9;11)(q34;p15) fuses NUP98 to a novel homeobox partner gene, PRRX2, in a therapy-related acute myeloid leukemia by Gervais, C, Mauvieux, L, Perrusson, N, Hélias, C, Struski, S, Leymarie, V, Lioure, B, Lessard, M

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Evaluation of ETF1/eRF1, mapping to 5q31, as a candidate myeloid tumor suppressor gene by Dubourg, Christèle, Toutain, Bertrand, Hélias, Catherine, Henry, Catherine, Lessard, Michel, Le Gall, Jean-Yves, Le Treut, André, Guenet, Lucienne

“…Interstitial deletion of the long arm of chromosome 5 is a recurrent abnormality, mainly associated with myelodysplastic syndromes (MDS) and acute myeloid…”
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NUP98 Is Fused to PRRX2, a New Homeobox Partner Gene in t(9;11)(q34;p15), in a Therapy-Related Acute Myeloid Leukemia by Gervais, Carine, Mauvieux, Laurent, Perrusson, Nathalie, Helias, Catherine, Struski, Stephanie, Leymarie, Vincent, Lioure, Bruno, Lessard, Michel

“…The nucleoporin gene NUP98 is known to be rearranged in several recurrent translocations occurring in de novo and therapy-related myelodysplastic syndrome and…”
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The t(14;19)(q32;q13) Translocation in B Lymphoproliferative Disorders: A Continuum from Chronic Lymphocytic Leukemia (CLL) to Marginal Zone Lymphoma (MZL)? by Nguyen-Khac, Florence, Chapiro, Elise, Radford-Weiss, Isabelle, Bastard, Christian, Dominique, Leroux, Callet-Bauchu, Evelyne, Talmant, Pascaline, Luquet, Isabelle, Marie-Joelle, Mozziconacci, Michel, Lessard, Sophie, Raynaud D., Davi, Frederic, Merle-Beral, Helene, Berger, Francoise, Berger, Roland

“…Translocation t(14;19)(q32;q13) juxtaposing BCL3 in 19q13 with IGH in 14q32, is a rare recurrent event found in patients with B-cell malignancies. So far, a…”
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ETV6 (TEL) gene amplification in a myelodysplastic syndrome with excess of blasts by MAUVIEUX, L, HELIAS, C, PERRUSSON, N, LIOURE, B, SOREL, N, BRIZARD, F, LESSARD, M

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