Search Results - "Lessa, Lucília M. A."

Mechanisms mediating the diuretic and natriuretic actions of the incretin hormone glucagon-like peptide-1 by Crajoinas, Renato O, Oricchio, Felipe T, Pessoa, Thaissa D, Pacheco, Bruna P M, Lessa, Lucília M A, Malnic, Gerhard, Girardi, Adriana C C

“…Glucagon-like peptide-1 (GLP-1) is a gut incretin hormone considered a promising therapeutic agent for type 2 diabetes because it stimulates beta cell…”
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Renal upregulation of NCC counteracts empagliflozin-mediated NHE3 inhibition in normotensive but not in hypertensive male rat by Castro, Paulo C, Santos-Rios, Thiago M, Martins, Flavia L, Crajoinas, Renato O, Caetano, Marcos V, Lessa, Lucília M A, Luchi, Weverton M, McCormick, James A, Girardi, Adriana C C

“…Sodium-glucose cotransporter-2 inhibitors (SGLT2i) reduce blood pressure (BP) in patients with hypertension, yet the precise molecular mechanisms remain…”
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Mechanisms underlying the inhibitory effects of uroguanylin on NHE3 transport activity in renal proximal tubule by Lessa, Lucília M A, Carraro-Lacroix, Luciene R, Crajoinas, Renato O, Bezerra, Camila N, Dariolli, Rafael, Girardi, Adriana C C, Fonteles, Manassés C, Malnic, Gerhard

“…We previously demonstrated that uroguanylin (UGN) significantly inhibits Na(+)/H(+) exchanger (NHE)3-mediated bicarbonate reabsorption. In the present study,…”
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Posttranslational mechanisms associated with reduced NHE3 activity in adult vs. young prehypertensive SHR by Crajoinas, Renato O, Lessa, Lucília M A, Carraro-Lacroix, Luciene R, Davel, Ana Paula C, Pacheco, Bruna P M, Rossoni, Luciana V, Malnic, Gerhard, Girardi, Adriana C C

“…Abnormalities in renal proximal tubular (PT) sodium transport play an important role in the pathophysiology of essential hypertension. The Na(+)/H(+) exchanger…”
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Uroguanylin inhibits H-ATPase activity and surface expression in renal distal tubules by a PKG-dependent pathway by da Silva Lima, Vanessa, Crajoinas, Renato O, Carraro-Lacroix, Luciene R, Godinho, Alana N, Dias, João L G, Dariolli, Rafael, Girardi, Adriana C C, Fonteles, Manassés C, Malnic, Gerhard, Lessa, Lucília M A

“…Cumulative evidence suggests that guanylin peptides play an important role on electrolyte homeostasis. We have previously reported that uroguanylin (UGN)…”
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Terpinen-4-ol: mechanisms of relaxation on rabbit duodenum by Nascimento, Nilberto R. F., Leal-Cardoso, José H., Lessa, Lucília M. A., Roriz-Filho, Jarbas S., Cunha, Karina M. A., Fonteles, Manassés C.

“…The effect of terpinen‐4‐ol was studied on rabbit duodenum in‐vitro. Terpinen‐4‐ol induced relaxation of the basal tonus (IC50 170.2 (95% confidence interval,…”
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Effect of uroguanylin on potassium and bicarbonate transport in rat renal tubules by Amorim, José Benedito Oliveira, Musa-Aziz, Raif, Lessa, Lucilia M A, Malnic, Gerhard, Fonteles, Manassés Claudino

“…The effect of uroguanylin (UGN) on K+ and H+ secretion in the renal tubules of the rat kidney was studied using in vivo stationary microperfusion. For the…”
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Effects of cardiotonic steroids on isolated perfused kidney and NHE3 activity in renal proximal tubules by Godinho, Alana N., Costa, Graciana T., Oliveira, Nádia O., Cardi, Bruno A., Uchoa, Daniel Esdras A., Silveira, Edilberto R., Quintas, Luis Eduardo M., Noël, François G., Fonteles, Manassés C., Carvalho, Krishnamurti M., Santos, Cláudia F., Lessa, Lucília M.A., do Nascimento, Nilberto R.F.

“…Cardiotonic steroids (CS) are known as modulators of sodium and water homeostasis. These compounds contribute to the excretion of sodium under overload…”
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Role of CFTR and ClC-5 in Modulating Vacuolar H+-ATPase Activity in Kidney Proximal Tubule by Carraro-Lacroix, Luciene R., Lessa, Lucília M.A., Bezerra, Camila N.A., Pessoa, Thaíssa D., Souza-Menezes, Jackson, Morales, Marcelo M., Girardi, Adriana C.C., Malnic, Gerhard

“…Background/Aims: It has been widely accepted that chloride ions moving along chloride channels act to dissipate the electrical gradient established by the…”
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