Search Results - "Lesperance, Mary L"

A statistical model for calibration and computation of detection and quantification limits for low copy number environmental DNA samples by Lesperance, Mary L., Allison, Michael J., Bergman, Lauren C., Hocking, Morgan D., Helbing, Caren C.

“…Environmental DNA (eDNA) has been increasingly utilized by academic, industry, and government groups for environmental monitoring due to its efficiency in…”
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Intervals Longer Than 20 Weeks From Breast-Conserving Surgery to Radiation Therapy Are Associated With Inferior Outcome for Women With Early-Stage Breast Cancer Who Are Not Receiving Chemotherapy by OLIVOTTO, Ivo A, LESPERANCE, Mary L, KWAN, Winkle, KENNECKE, Hagen, TRUONG, Pauline T, NICHOL, Alan, BERRANG, Tanya, TYLDESLEY, Scott, GERMAIN, Francois, SPEERS, Caroline, WAI, Elaine, HOLLOWAY, Caroline

“…To determine the interval from breast-conserving surgery (BCS) to radiation therapy (RT) that affects local control or survival. The 10-year Kaplan-Meier (KM)…”
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Effect of radiotherapy boost and hypofractionation on outcomes in ductal carcinoma in situ by Wai, Elaine S., Lesperance, Mary L., Alexander, Cheryl S., Truong, Pauline T., Culp, Matthew, Moccia, Patricia, Lindquist, Jennifer F., Olivotto, Ivo A.

“…BACKGROUND: Boost radiotherapy (RT) improves outcomes for patients with invasive breast cancer, but whether this is applicable to patients with pure ductal…”
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Systolic blood pressure as a predictor of transient ischemic attack/minor stroke in emergency department patients under age 80: a prospective cohort study by Penn, Andrew M, Croteau, Nicole S, Votova, Kristine, Sedgwick, Colin, Balshaw, Robert F, Coutts, Shelagh B, Penn, Melanie, Blackwood, Kaitlin, Bibok, Maximilian B, Saly, Viera, Hegedus, Janka, Yu, Amy Y X, Zerna, Charlotte, Klourfeld, Evgenia, Lesperance, Mary L

“…Elevated blood pressure (BP) at emergency department (ED) presentation and advancing age have been associated with risk of ischemic stroke; however, the…”
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Establishing the Signal above the Noise: Accounting for an Environmental Background in the Detection and Quantification of Salmonid Environmental DNA by Hocking, Morgan D., MacAdams, Jeffrey C., Allison, Michael J., Bergman, Lauren C., Sneiderman, Robert, Koop, Ben F., Starzomski, Brian M., Lesperance, Mary L., Helbing, Caren C.

“…A current challenge for environmental DNA (eDNA) applications is how to account for an environmental (or false-positive) background in surveys. We performed…”
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Reducing time-to-unit among patients referred to an outpatient stroke assessment unit with a novel triage process: a prospective cohort study by Bibok, Maximilian B, Votova, Kristine, Balshaw, Robert F, Lesperance, Mary L, Croteau, Nicole S, Trivedi, Anurag, Morrison, Jaclyn, Sedgwick, Colin, Penn, Andrew M

“…To evaluate the performance of a novel triage system for Transient Ischemic Attack (TIA) units built upon an existent clinical prediction rule (CPR) to reduce…”
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Simultaneous prediction of multiple outcomes using revised stacking algorithms by Xing, Li, Lesperance, Mary L, Zhang, Xuekui

“…Abstract Motivation HIV is difficult to treat because its virus mutates at a high rate and mutated viruses easily develop resistance to existing drugs. If the…”
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Piecewise Regression: A Tool for Identifying Ecological Thresholds by Toms, Judith D., Lesperance, Mary L.

“…We demonstrate the use of piecewise regression as a statistical technique to model ecological thresholds. Recommended procedures for analysis are illustrated…”
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Comparison of transcriptome responses of the liver, tail fin, and olfactory epithelium of Rana [Lithobates] catesbeiana tadpoles disrupted by thyroid hormones and estrogen by Jackman, Shireen H., Evans, Ellis P., Kuecks-Winger, Haley N., Corrie, Lorissa M., Imbery, Jacob J., Miliano, Rachel C., Robert, Bonnie J., Thompson, Vanessa C., Thambirajah, Anita A., Lesperance, Mary L., Pyle, Gregory G., van Aggelen, Graham, Helbing, Caren C.

“…•Thyroid hormones (THs) are important in vertebrates and are contaminant targets.•Estradiol (E2) may crosstalk with thyroxine (T4) and triiodothyronine…”
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White Matter Hyperintensity Volume Influences Symptoms in Patients Presenting With Minor Neurological Deficits by Zerna, Charlotte, Yu, Amy Y.X., Hong, Zachary M., Penn, Andrew M., Lesperance, Mary L., Croteau, Nicole S., Balshaw, Robert F., Votova, Kristine, Bibok, Maximilian B., Saly, Viera, Modi, Jayesh, Hegedus, Janka, Klourfeld, Evgenia, Coutts, Shelagh B.

“…BACKGROUND AND PURPOSE—Acute minor neurological deficits are a common complaint in the emergency department and differentiation of transient ischemic…”
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Verification of a proteomic biomarker panel to diagnose minor stroke and transient ischaemic attack: phase 1 of SpecTRA, a large scale translational study by Penn, Andrew M., Bibok, Maximilian B., Saly, Viera K., Coutts, Shelagh B., Lesperance, Mary L., Balshaw, Robert F., Votova, Kristine, Croteau, Nicole S., Trivedi, Anurag, Jackson, Angela M., Hegedus, Janka, Klourfeld, Evgenia, Yu, Amy Y. X., Zerna, Charlotte, Borchers, Christoph H.

“…Objective: To derive a plasma biomarker protein panel from a list of 141 candidate proteins which can differentiate transient ischaemic attack (TIA)/minor…”
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Validation of a proteomic biomarker panel to diagnose minor-stroke and transient ischaemic attack: phase 2 of SpecTRA, a large scale translational study by Penn, Andrew M., Bibok, Maximilian B., Saly, Viera K., Coutts, Shelagh B., Lesperance, Mary L., Balshaw, Robert F., Votova, Kristine, Croteau, Nicole S., Trivedi, Anurag, Jackson, Angela M., Hegedus, Janka, Klourfeld, Evgenia, Yu, Amy Y. X., Zerna, Charlotte, Modi, Jayesh, Barber, Philip A., Hoag, Gordon, Borchers, Christoph H.

“…OBJECTIVE: To validate our previously developed 16 plasma-protein biomarker panel to differentiate between transient ischaemic attack (TIA) and…”
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In the absence of cancer registry data, is it sensible to assess incidence using hospital separation records? by Brackley, Moyra E, Penning, Margaret J, Lesperance, Mary L

“…Within the health literature, a major goal is to understand distribution of service utilisation by social location. Given equivalent access, differential…”
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Predictors of Local Recurrence in a Population-Based Cohort of Women with Ductal Carcinoma In Situ Treated with Breast Conserving Surgery Alone by Wai, Elaine S., Lesperance, Mary L., Alexander, Cheryl S., Truong, Pauline T., Moccia, Patrizia, Culp, Matthew, Lindquist, Jennifer, Olivotto, Ivo A.

“…Background To identify prognostic indicators of local recurrence (LR) in patients with ductal carcinoma in situ (DCIS) of the breast treated with breast…”
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Time to stop progesterone receptor testing in breast cancer management by Olivotto, Ivo A, Truong, Pauline T, Speers, Caroline H, Bernstein, Vanessa, Allan, Sharon J, Kelly, Seamus J, Lesperance, Mary L

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An Algorithm for Computing the Nonparametric MLE of a Mixing Distribution by Lesperance, Mary L., Kalbfleisch, John D.

“…A fast algorithm for calculating the nonparametric maximum likelihood estimate (MLE) of a mixing distribution, G(·). in a mixture model is discussed. The…”
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PIECEWISE REGRESSION: A TOOL FOR IDENTIFYING ECOLOGICAL THRESHOLDS by Toms, Judith D., Lesperance, Mary L.

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Abstract P2-14-02: Complications of breast reconstruction in a provincial population of breast cancer survivors by Wai, Elaine S, Lu, Ling Hong, Alexander, Cheryl, Lesperance, Mary L, McBride, Mary L, Tyldesley, Scott, Taylor, Chris

“…Abstract Background: Breast cancer is the most prevalent cancer in women in Canada. There are varying reports of the use of breast reconstruction in various…”
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Abstract TMP95: Large Centralized TIA Assessment Unit Associated With Reduction of Recurrent Stroke by up to 70 by Penn, Andrew M, Maclure, Malcolm, Lu, Linghong, Bibok, Maximilian B, Morrison, Jaclyn L, Votova, Kristine, Penn, Melanie, Balshaw, Robert, Lesperance, Mary L

“…Abstract only Introduction: Transient neurological symptoms are a common presentation in emergency departments (ED). Access to stroke specialists and advanced…”
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Discussion on A. Desmond's paper: Optimal estimating functions, quasi-likelihood and statistical modelling by Lesperance, Mary L.

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