Search Results - "Lesniewski, Richard R."

A potent erythropoietin-mimicking human antibody interacts through a novel binding site by Liu, Zhihong, Stoll, Vincent S., DeVries, Peter J., Jakob, Clarissa G., Xie, Nancy, Simmer, Robert L., Lacy, Susan E., Egan, David A., Harlan, John E., Lesniewski, Richard R., Reilly, Edward B.

“…Recombinant human erythropoietin (rHu-EPO) is used to treat anemia by activating the erythropoietin receptor (EPOR) in erythroid progenitor cells, leading to…”
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The Potency of Erythropoietin-Mimic Antibodies Correlates Inversely with Affinity by Lacy, Susan E, DeVries, Peter J, Xie, Nancy, Fung, Emma, Lesniewski, Richard R, Reilly, Edward B

“…Preclinical animal studies have shown that Ab12.6, an agonistic human Ab targeting the erythropoietin receptor (EPOR), exhibits several potential dosing and…”
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Thrombospondin-1 Mimetic Peptide Inhibitors of Angiogenesis and Tumor Growth:  Design, Synthesis, and Optimization of Pharmacokinetics and Biological Activities by Haviv, Fortuna, Bradley, Michael F, Kalvin, Douglas M, Schneider, Andrew J, Davidson, Donald J, Majest, Sandra M, McKay, Laura M, Haskell, Catherine J, Bell, Randy L, Nguyen, Bach, Marsh, Kennan C, Surber, Bruce W, Uchic, John T, Ferrero, James, Wang, Yi-Chun, Leal, Juan, Record, Rae D, Hodde, Jason, Badylak, Stephen F, Lesniewski, Richard R, Henkin, Jack

“…The heptapeptide 1, NAc-Gly-Val-DIle-Thr-Arg-Ile-ArgNHEt, a structurally modified fragment derived from the second type-1 repeat of thrombospondin-1 (TSP-1),…”
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Lack of Protective Immunity Against Reinfection with Hepatitis C Virus by Farci, Patrizia, Alter, Harvey J., Govindarajan, Sugantha, Wong, Doris C., Engle, Ronald, Lesniewski, Richard R., Mushahwar, Isa K., Desai, Suresh M., Miller, Roger H., Ogata, Norio, Purcell, Robert H.

“…Some individuals infected with hepatitis C virus (HCV) experience multiple episodes of acute hepatitis. It is unclear whether these episodes are due to…”
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Persistent hepatitis C virus infection after liver transplantation: clinical and virological features by Gretch, D R, Bacchi, C E, Corey, L, dela Rosa, C, Lesniewski, R R, Kowdley, K, Gown, A, Frank, I, Perkins, J D, Carithers, Jr, R L

“…We report a prospective clinical and virological study of 18 patients undergoing orthotopic liver transplantation, selected because of hepatitis C virus (HCV)…”
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Detection and distribution of hepatitis C-specific antigens in naturally infected liver by Blight, K, Lesniewski, R R, LaBrooy, J T, Gowans, E J

“…Hepatitis C virus antigen expression was examined using peptide antibodies in liver tissue taken at biopsy from four chronic carriers of hepatitis C virus…”
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Significance of anti-E2 in the diagnosis of HCV infection in patients on maintenance hemodialysis: anti-E2 is frequently detected among anti-HCV antibody-negative patients by Lee, D S, Lesniewski, R R, Sung, Y C, Min, W K, Park, S G, Lee, K H, Kim, H S

“…A routine screening test used in the diagnosis of hepatitis C virus (HCV) infection is the anti-HCV antibody (anti-HCV) test containing core, NS3, NS4, and NS5…”
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Immunohistochemical detection of the NS4 antigen of hepatitis C virus and its relation to histopathology by Blight, K, Rowland, R, Hall, PD, Lesniewski, RR, Trowbridge, R, LaBrooy, JT, Gowans, EJ

“…The immunohistochemical localization of the hepatitis C virus (HCV) nonstructural antigen 4 (NS4) was investigated in formalin-fixed human liver biopsy samples…”
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Hypervariable 5'-terminus of hepatitis C virus E2/NS1 encodes antigenically distinct variants by Lesniewski, R R, Boardway, K M, Casey, J M, Desai, S M, Devare, S G, Leung, T K, Mushahwar, I K

“…Synthetic peptides representing sequences encoded at the 5'-terminus of E2/NS1 in hepatitis C virus (HCV) were constructed. Peptides synthesized based on the…”
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IgM-antibody response to hepatitis C virus antigens in acute and chronic post-transfusion non-A, non-B hepatitis by Chau, K H, Dawson, G J, Mushahwar, I K, Gutierrez, R A, Johnson, R G, Lesniewski, R R, Mattsson, L, Weiland, O

“…A specific IgM solid-phase enzyme-linked immunoassay for the diagnosis of a recent infection by hepatitis C virus (HCV) was developed. The assay utilizes a…”
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Risk of liver disease in HCV-seropositive kidney transplant recipients by Rohr, M S, Lesniewski, R R, Rubin, C A, Johnson, R G, Heise, E R, McDonald, J C, Adams, P L

“…This study determined whether renal allograft recipients with antibodies to hepatitis C virus (HCV) at the time of transplantation experienced increased…”
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Purine nucleoside and purine base concentrations in bovine thyroid and plasma by McMahon, K K, Lesniewski, R R, Fischer, A G

“…Concentrations of eight purine nucleosides and bases in bovine thyroid and plasma were determined by high pressure liquid chromatography. Plasma purines were…”
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