Search Results - "Lesniak, Maxine A."

New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut by Qiang, Xiaoling, Liotta, Anthony S., Shiloach, Joseph, Gutierrez, J. C., Wang, Haichao, Ochani, Mahendar, Ochani, Kanta, Yang, Huan, Rabin, Aviva, LeRoith, Derek, Lesniak, Maxine A., Böhm, Markus, Maaser, Christian, Kannengiesser, Klaus, Donowitz, Mark, Rabizadeh, Shervin, Czura, Christopher J., Tracey, Kevin J., Westlake, Mark, Zarfeshani, Aida, Mehdi, Syed F., Danoff, Ann, Ge, Xueliang, Sanyal, Suparna, Schwartz, Gary J., Roth, Jesse

“…E. coli releases a 33 amino acid peptide melanocortin-like peptide of E. coli (MECO-1) that is identical to the C-terminus of the E. coli elongation factor-G…”
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Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes by Haft, C R, de la Luz Sierra, M, Bafford, R, Lesniak, M A, Barr, V A, Taylor, S I

“…Sorting nexin (SNX) 1 and SNX2 are mammalian orthologs of Vps5p, a yeast protein that is a subunit of a large multimeric complex, termed the retromer complex,…”
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Specificity spillover at the hormone receptor--exploring its role in human disease by Fradkin, J E, Eastman, R C, Lesniak, M A, Roth, J

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Insulin Receptor Substrate-2 (IRS-2) Can Mediate the Action of Insulin to Stimulate Translocation of GLUT4 to the Cell Surface in Rat Adipose Cells by Zhou, Lixin, Chen, Hui, Lin, Chung H., Cong, Li-Na, McGibbon, Margaret A., Sciacchitano, Salvatore, Lesniak, Maxine A., Quon, Michael J., Taylor, Simeon I.

“…Insulin receptor substrates-1 and -2 (IRS-1 and -2) are important substrates of the insulin receptor tyrosine kinase. Previous studies have focused upon the…”
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Studies on binding and mitogenic effect of insulin and insulin-like growth factor I in glomerular mesangial cells by Conti, F G, Striker, L J, Lesniak, M A, MacKay, K, Roth, J, Striker, G E

“…The mesangial cells, as part of their smooth muscle cell function, are actively involved in regulating glomerular hemodynamics. Their overlying endothelium is…”
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The evolutionary origins of hormones, neurotransmitters, and other extracellular chemical messengers: implications for mammalian biology by Roth, J, LeRoith, D, Shiloach, J, Rosenzweig, J L, Lesniak, M A, Havrankova, J

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Normal coding sequence of insulin gene in Pima Indians and Nauruans, two groups with highest prevalence of type II diabetes by RABEN, N, BARBETTI, F, CAMA, A, LESNIAK, M. A, LILLIOJA, S, ZIMMET, P, SERJEANTSON, S. W, TAYLOR, S. I, ROTH, J

“…The nucleotide sequence of the insulin gene was determined in American Pima Indians and Micronesian Nauruans, two populations in whom the prevalence of…”
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The insulin receptors of chick embryo show tissue-specific structural differences which parallel those of the insulin-like growth factor I receptors by Bassas, L, de Pablo, F, Lesniak, M A, Roth, J

“…Since specific binding to receptors and biological effects of insulin and insulin-like growth factors (IGFs) are demonstrable soon after the neural tube closes…”
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Pituitary dwarfism in a patient with circulating abnormal growth hormone polymers by Valenta, L J, Sigel, M B, Lesniak, M A, Elias, A N, Lewis, U J, Friesen, H G, Kershnar, A K

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In vivo imaging of insulin receptors in monkeys using 18F-labeled insulin and positron emission tomography by EASTMAN, R. C, CARSON, R. E, LESNIAK, M. A, ROTH, J, JACOBSON, K. A, YECHIAL SHAI, CHANNING, M. A, DUNN, B. B, BACHER, J. D, BAAS, E, JONES, E, KIRK, K. L

“…We previously described a prosthetic group methodology for incorporating 18F into peptides and showed that 18F-labeled insulin (18F-insulin) binds to insulin…”
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Fluorine-18 labeled insulin: a prosthetic group methodology for incorporation of a positron emitter into peptides and proteins by Shai, Yechiel, Kirk, Kenneth L, Channing, Michael A, Dunn, Bonnie B, Lesniak, Maxine A, Eastman, Richard C, Finn, Ronald D, Roth, Jesse, Jacobson, Kenneth A

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Genetic differences in susceptibility of pancreatic β cells to virus-induced diabetes mellitus by YOON, JI-WON, LESNIAK, MAXINE A, FUSSGANGER, ROLF, LOUIS NOTKINS, ABNER

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Variant sequences of insulin receptor substrate-1 in patients with noninsulin-dependent diabetes mellitus by Imai, Y, Fusco, A, Suzuki, Y, Lesniak, M A, D'Alfonso, R, Sesti, G, Bertoli, A, Lauro, R, Accili, D, Taylor, S I

“…The pathophysiology of noninsulin-dependent diabetes mellitus (NIDDM) is characterized by insulin resistance and insulin deficiency. To search for genetic…”
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Water-soluble specific growth hormone binding sites from cultured human lymphocytes: preparation and partial characterization by McGuffin, Jr, W L, Gavin, 3rd, J R, Lesniak, M A, Gorden, P, Roth, J

“…Cultured human lymphocytes (IM-9 cell line) have specific binding sites or receptors for human growth hormone (hGH). Under appropriate conditions, this…”
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Insulin in brain and other extrapancreatic tissues of vertebrates and nonvertebrates by Le Roith, D, Hendricks, S A, Lesniak, M A, Rishi, S, Becker, K L, Havrankova, J, Rosenzweig, J L, Brownstein, M J, Roth, J

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Binding of 125I-Human Growth Hormone to Specific Receptors in Human Cultured Lymphocytes by Lesniak, Maxine A., Gorden, Phillip, Roth, Jesse, Gavin, James R.

“…The interaction of human growth hormone with human lymphocytes from an established culture (IM-9) was studied using 125I-human growth hormone. The binding of…”
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Human Growth Hormone Radioreceptor Assay using Cultured Human Lymphocytes by LESNIAK, MAXINE A, ROTH, JESSE, GORDEN, PHILLIP, GAVIN, JAMES R

“…RADIOMMUNOASSAY has been widely applied to the measurement of circulating growth hormone. Although sensitive and precise methods for measuring immunoreactive…”
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Receptors for insulin-like growth factors I and II: autoradiographic localization in rat brain and comparison to receptors for insulin by Lesniak, M A, Hill, J M, Kiess, W, Rojeski, M, Pert, C B, Roth, J

“…Receptors for insulin-like growth factor I (IGF-I) in rat brain were visualized using autoradiography with [125I]IGF-I. The binding of the labeled peptide was…”
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Ontogeny of receptors for insulin-like peptides in chick embryo tissues: early dominance of insulin-like growth factor over insulin receptors in brain by Bassas, L, de Pablo, F, Lesniak, M A, Roth, J

“…Recently, we confirmed early data showing deleterious effects of exogenous insulin on chick embryos at 2 days of development, although insulin receptors were…”
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Insulin and insulin-like growth factor I both stimulate metabolism, growth, and differentiation in the postneurula chick embryo by Girbau, M, Gomez, J A, Lesniak, M A, de Pablo, F

“…Chick embryos after 48 h of development (day 2) maintained in ovo provide an adequate model to study hormonal influences in early organogenesis in vertebrates…”
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