Search Results - "Leslie, Kevin W"

Development and Scale-Up of an Asymmetric Synthesis of AZD8186 Using the Fukuyama Modification of the Mitsunobu Reaction by Moore, Peter R, Muir, James C, Dubiez, Jerome, Leslie, Kevin W, Tomlin, Paula, McCormick, Marc, Janbon, Sophie L, Cornwall, Philip, Ryberg, Per, Berg, Robert

“…A large-scale asymmetric synthesis has been developed for the kilo-lab manufacture of AZD8186. The process initially employs a regioselective Heck coupling in…”
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Rapid virtual screening of enantioselective catalysts using CatVS by Rosales, Anthony R., Wahlers, Jessica, Limé, Elaine, Meadows, Rebecca E., Leslie, Kevin W., Savin, Rhona, Bell, Fiona, Hansen, Eric, Helquist, Paul, Munday, Rachel H., Wiest, Olaf, Norrby, Per-Ola

“…The development of computational tools to support organic synthesis, including the prediction of reaction pathways, optimization and selectivity, is a topic of…”
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Synthetic Route Design of AZD4635, an A2AR Antagonist by Littleson, Mairi M, Campbell, Andrew D, Clarke, Adam, Dow, Mark, Ensor, Gareth, Evans, Matthew C, Herring, Adam, Jackson, Bethany A, Jackson, Lucinda V, Karlsson, Staffan, Klauber, David J, Legg, Danny H, Leslie, Kevin W, Moravčík, Štefan, Parsons, Chris D, Ronson, Thomas O, Meadows, Rebecca E

“…The AstraZeneca approach to synthetic Route Design is exemplified through our AZD4635 chemical development program. The identification of possible new route…”
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Synthetic Route Design of AZD4635, an A 2A R Antagonist by Littleson, Mairi M., Campbell, Andrew D., Clarke, Adam, Dow, Mark, Ensor, Gareth, Evans, Matthew C., Herring, Adam, Jackson, Bethany A., Jackson, Lucinda V., Karlsson, Staffan, Klauber, David J., Legg, Danny H., Leslie, Kevin W., Moravčík, Štefan, Parsons, Chris D., Ronson, Thomas O., Meadows, Rebecca E.

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