Search Results - "Lesley, Jayne"

Hyaluronan Binding by Cell Surface CD44 by Lesley, J.

“…CD44 is the primary cell surface receptor for the extracellular matrix glycosaminoglycan hyaluronan. Here we determined the relative avidities of unlabeled…”
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TSG-6 Modulates the Interaction between Hyaluronan and Cell Surface CD44 by Lesley, Jayne, Gál, István, Mahoney, David J., Cordell, Martin R., Rugg, Marilyn S., Hyman, Robert, Day, Anthony J., Mikecz, Katalin

“…Interactions between CD44 and hyaluronan are implicated in the primary adhesion of lymphocytes to endothelium at inflammatory locations. Here we show that…”
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Targeting rat anti-mouse transferrin receptor monoclonal antibodies through blood-brain barrier in mouse by Lee, H J, Engelhardt, B, Lesley, J, Bickel, U, Pardridge, W M

“…Drug targeting through the brain capillary endothelium, which forms the blood-brain barrier (BBB) in vivo, may be achieved with peptidomimetic monoclonal…”
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Hyaluronan Binding Properties of a CD44 Chimera Containing the Link Module of TSG-6 by Lesley, Jayne, English, Nicole M., Gál, István, Mikecz, Katalin, Day, Anthony J., Hyman, Robert

“…CD44, a cell-surface receptor for the extracellular matrix glycosaminoglycan hyaluronan, can mediate leukocyte rolling on hyaluronan substrates and has been…”
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Site-specific De-N-glycosylation of CD44 can activate hyaluronan binding, and CD44 activation states show distinct threshold densities for hyaluronan binding by ENGLISH, N. M, LESLEY, J. F, HYMAN, R

“…CD44 is a cell surface receptor for the glycosaminoglycan hyaluronan (HA). Not all CD44-positive cells bind HA, and binding ability is strictly regulated…”
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Role of the Extracellular and Cytoplasmic Domains of CD44 in the Rolling Interaction of Lymphoid Cells with Hyaluronan under Physiologic Flow by Gal, Istvan, Lesley, Jayne, Ko, Wendy, Gonda, Andrea, Stoop, Reinout, Hyman, Robert, Mikecz, Katalin

“…CD44 can function as an adhesion receptor that mediates leukocyte rolling on hyaluronan (HA). To study the contributions of different domains of the standard…”
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Binding of hyaluronic acid to lymphoid cell lines is inhibited by monoclonal antibodies against Pgp-1 by Lesley, J, Schulte, R, Hyman, R

“…Recent biochemical and sequence data suggest a possible relationship between Pgp-1 (identical to CD44/Hermes 1/p85) and a hyaluronic acid-binding function…”
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Role of CD44 cytoplasmic domain in hyaluronan binding by Perschl, A, Lesley, J, English, N, Trowbridge, I, Hyman, R

“…The hyaluronan (HA) binding activity of mutant CD44 constructs expressed in AKR1 T-lymphoma cells was evaluated by flow cytometry using fluorescein-conjugated…”
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Transmembrane domain of CD44 is required for its detergent insolubility in fibroblasts by Perschl, A, Lesley, J, English, N, Hyman, R, Trowbridge, I S

“…The hyaluronan receptor CD44 is an abundant glycoprotein expressed on a variety of different cell types. In fibroblasts a significant portion of receptor…”
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A study investigating the validity of an accelerometer in quantification of step count in adult hospital inpatients recovering from critical illness by Anderson, Jayne Lesley, Yoward, L Samantha, Green, Angela J

“…Objective: To determine the validity of the ActiGraph GT3X accelerometer in step count quantification when compared to observed step count in hospitalised…”
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An Exploration of Teacher Perceptions of Collective Teacher Efficacy Beliefs and the Enabling Conditions that Impact Collective Efficacy in High and Low Performing Schools by Machado, Lesley Jayne

“…This quantitative study was conducted to determine (a) if there was a difference in collective teacher efficacy beliefs of teachers who taught in…”
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Narrative review of lead poisoning in humans caused by industrial activities and measures compatible with sustainable industrial activities in Republic of Zambia by Nakata, Hokuto, Nakayama, Shouta M.M., Yabe, John, Muzandu, Kaampwe, Kataba, Andrew, Ikeda-Araki, Atsuko, Drisse, Marie-Noel Brune, Onyon, Lesley Jayne, Gorman, Julia, Kritika, Poudel, Fukunaga, Hisanori, Ikenaka, Yoshinori, Kishi, Reiko, Ishizuka, Mayumi

“…Lead (Pb) pollution and human exposure to Pb, is an important issue for the international community to address being associated with 0.90 million deaths from…”
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Hyaluronan binding by cell surface CD44 by Lesley, J, Hascall, V C, Tammi, M, Hyman, R

“…CD44 is the primary cell surface receptor for the extracellular matrix glycosaminoglycan hyaluronan. Here we determined the relative avidities of unlabeled…”
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Modulation of transferrin receptor expression and function by anti-transferrin receptor antibodies and antibody fragments by Lesley, J, Schulte, R, Woods, J

“…It has been suggested that effects of anti-transferrin receptor antibodies on cell growth and receptor expression are the result of varying degrees of receptor…”
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Biochemical characterization and cellular distribution of a polymorphic, murine cell-surface glycoprotein expressed on lymphoid tissues by Trowbridge, I S, Lesley, J, Schulte, R, Hyman, R, Trotter, J

“…A murine leukocyte surface glycoprotein (Mr = 95 000) has been defined by means of xenogeneic monoclonal antibodies. In normal hematopoietic tissues, the…”
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Validity of the actigraph gt3x accelerometer in identification of body position and step count in adult hospitalised patients recovering from critical illness by Anderson, Jayne Lesley

“…Purpose: Physical recovery from critical illness is complicated by neuromuscular weakness. Evidence suggests mobility commencing within the intensive care unit…”
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Expression of transferrin receptor on murine hematopoietic progenitors by Lesley, J, Hyman, R, Schulte, R, Trotter, J

“…We have used a monoclonal antibody against the murine transferrin receptor to study the expression of the transferrin receptor on the hematopoietic progenitor…”
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Use of formalin-fixed paraffin-embedded tumor tissue as a DNA source in molecular epidemiological studies of pediatric CNS tumors by Ferguson, Anthea Elizabeth, Cohn, Richard Julian, Ashton, Lesley Jayne

“…Formalin-fixed paraffin-embedded tissue (FFPET) samples are a potential source of DNA for molecular epidemiological studies. However, the use of FFPET samples…”
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CD44 and its interaction with extracellular matrix by Lesley, J, Hyman, R, Kincade, P W

“…It is now generally accepted that CD44 is a cell adhesion receptor and that hyaluronan is one of its ligands. Like many cell adhesion receptors, CD44 is…”
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Effects of monoclonal antibodies that block transferrin receptor function on the in vivo growth of a syngeneic murine leukemia by SAUVAGE, C. A, MENDELSOHN, J. C, LESLEY, J. F, TROWBRIDGE, I. S

“…The ability of monoclonal antibodies (MAbs) against the murine transferrin receptor to inhibit the growth of transplanted syngeneic AKR/J SL-2 leukemic cells…”
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