Search Results - "Leskov, Ilya"

Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis by Novershtern, Noa, Subramanian, Aravind, Lawton, Lee N., Mak, Raymond H., Haining, W. Nicholas, McConkey, Marie E., Habib, Naomi, Yosef, Nir, Chang, Cindy Y., Shay, Tal, Frampton, Garrett M., Drake, Adam C.B., Leskov, Ilya, Nilsson, Bjorn, Preffer, Fred, Dombkowski, David, Evans, John W., Liefeld, Ted, Smutko, John S., Chen, Jianzhu, Friedman, Nir, Young, Richard A., Golub, Todd R., Regev, Aviv, Ebert, Benjamin L.

“…Though many individual transcription factors are known to regulate hematopoietic differentiation, major aspects of the global architecture of hematopoiesis…”
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Sensitizing Protective Tumor Microenvironments to Antibody-Mediated Therapy by Pallasch, Christian P., Leskov, Ilya, Braun, Christian J., Vorholt, Daniela, Drake, Adam, Soto-Feliciano, Yadira M., Bent, Eric H., Schwamb, Janine, Iliopoulou, Bettina, Kutsch, Nadine, van Rooijen, Nico, Frenzel, Lukas P., Wendtner, Clemens M., Heukamp, Lukas, Kreuzer, Karl Anton, Hallek, Michael, Chen, Jianzhu, Hemann, Michael T.

“…Therapy-resistant microenvironments represent a major barrier toward effective elimination of disseminated malignancies. Here, we show that select…”
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Urrets-Zavalia syndrome following placement of scleral-sutured intraocular lens by Sylla, Mohamed M., Gelnick, Samuel, Leskov, Ilya

“…To report a novel case of Urrets-Zavalia syndrome (UZS). A 59-year-old man underwent removal of a dislocated intraocular lens and placement of a…”
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Human CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID Il2rγ-/- (NSG) mice by Drake, Adam C, Khoury, Maroun, Leskov, Ilya, Iliopoulou, Bettina P, Fragoso, Maria, Lodish, Harvey, Chen, Jianzhu

“…Increasing demand for human hematopoietic stem cells (HSCs) in clinical and research applications necessitates expansion of HSCs in vitro. Before these cells…”
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Antigen-bearing dendritic cells regulate the diverse pattern of memory CD8 T-cell development in different tissues by Shen, Ching-Hung, Talay, Oezcan, Mahajan, Vinay S., Leskov, Ilya B., Eisen, Herman N., Chen, Jianzhu

“…Memory T cells of the effector type (T EM ) account for the characteristic rapidity of memory T-cell responses, whereas memory T cells of the central type (T…”
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Phosducin facilitates light-driven transducin translocation in rod photoreceptors. Evidence from the phosducin knockout mouse by Sokolov, Maxim, Strissel, Katherine J, Leskov, Ilya B, Michaud, Norman A, Govardovskii, Viktor I, Arshavsky, Vadim Y

“…Phosducin is a photoreceptor-specific protein known to interact with the beta gamma subunits of G proteins. In pursuit of the function of phosducin, we tested…”
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The DEP Domain Determines Subcellular Targeting of the GTPase Activating Protein RGS9 In Vivo by Martemyanov, Kirill A, Lishko, Polina V, Calero, Nidia, Keresztes, Gabor, Sokolov, Maxim, Strissel, Katherine J, Leskov, Ilya B, Hopp, Johnathan A, Kolesnikov, Alexander V, Chen, Ching-Kang, Lem, Janis, Heller, Stefan, Burns, Marie E, Arshavsky, Vadim Y

“…DEP (for Disheveled, EGL-10, Pleckstrin) homology domains are present in numerous signaling proteins, including many in the nervous system, but their function…”
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Homeostasis of T Cell Diversity by Mahajan, Vinay S, Leskov, Ilya B, Chen, Jian Zhu

“…T cell homeostasis commonly refers to the maintenance of relatively stable T cell numbers in the peripheral lymphoid organs. Among the large numbers of T cells…”
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Diffuse Uveal Melanocytic Proliferation With Primary Vitreoretinal Lymphoma by Leskov, Ilya, Lyon, Alice T, Jampol, Lee M

“…Bilateral diffuse uveal melanocytic proliferation is a rare sign of several systemic malignant neoplasms. A patient presenting with uveal melanocytic…”
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SEROUS MACULAR DETACHMENT ASSOCIATED WITH WALDENSTROM MACROGLOBULINEMIA MANAGED WITH IBRUTINIB: A CASE REPORT AND NEW INSIGHTS INTO PATHOGENESIS by Leskov, Ilya, Knezevic, Alexander, Gill, Manjot K.

“…To report a case of serous macular detachment in a patient with Waldenstrom macroglobulinemia treated with ibrutinib. The patient underwent a complete…”
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Laser Therapy Versus Anti-VEGF Agents for Treatment of Retinopathy of Prematurity by Leskov, Ilya, Mukai, Shizuo

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Age-Related Differences in Ocular Features of a Naturalistic Free-Ranging Population of Rhesus Macaques by Fernandes, Arthur G, Alexopoulos, Palaiologos, Burgos-Rodriguez, Armando, Martinez, Melween I, Ghassibi, Mark, Leskov, Ilya, Brent, Lauren J N, Snyder-Mackler, Noah, Danias, John, Wollstein, Gadi, Higham, James P, Melin, Amanda D

“…Rhesus macaques (Macaca mulatta) are the premier nonhuman primate model for studying human health and disease. We investigated if age was associated with…”
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Phage Immunoprecipitation Sequencing of Autoantigens in Autoimmune Retinopathy by Davoudi, Samaneh, Ahmadi, Tina, Papavasilieou, Evangelia, Leskov, Ilya, Sobrin, Lucia

“…To identify autoantigens in autoimmune retinopathy patients by phage immunoprecipitation sequencing (PhIP-Seq), a new technique for autoantigen discovery…”
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Hypometabolic Lateral Recti Due to Bilateral Cranial Nerve VI Palsy by Leskov, Ilya, Rasool, Nailyn, Cestari, Dean M

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The Proteome of Preretinal Tissue in Proliferative Vitreoretinopathy by Miller, Charles G, Henderson, Matthew, Mantopoulos, Dimosthenis, Leskov, Ilya, Greco, Todd, Schwarzbauer, Jean E, Prenner, Jonathan L

“…Proliferative vitreoretinopathy (PVR) is the leading cause of retinal detachment repair failure. However, the molecular pathogenesis remains incompletely…”
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A NOVEL APPROACH TO SCLERAL FIXATION OF POSTERIOR CHAMBER INTRAOCULAR LENSES AND CAPSULAR TENSION RINGS AND SEGMENTS IN DEEP-SET EYES by Miller, Charles G., Minkus, Caroline, Lyon, Alice T., Basti, Surendra, Leskov, Ilya

“…To demonstrate a novel approach to scleral fixation of posterior chamber intraocular lenses and capsular tension rings and segments in deep-set eyes using the…”
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Phosducin Facilitates Light-driven Transducin Translocation in Rod Photoreceptors by Sokolov, Maxim, Strissel, Katherine J., Leskov, Ilya B., Michaud, Norman A., Govardovskii, Viktor I., Arshavsky, Vadim Y.

“…Phosducin is a photoreceptor-specific protein known to interact with the βγ subunits of G proteins. In pursuit of the function of phosducin, we tested the…”
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Mesenchymal stem cells secreting angiopoietin-like-5 support efficient expansion of human hematopoietic stem cells without compromising their repopulating potential by Khoury, Maroun, Drake, Adam, Chen, Qingfeng, Dong, Di, Leskov, Ilya, Fragoso, Maria F, Li, Yan, Iliopoulou, Bettina P, Hwang, William, Lodish, Harvey F, Chen, Jianzhu

“…Clinical and preclinical applications of human hematopoietic stem cells (HSCs) are often limited by scarcity of cells. Expanding human HSCs to increase their…”
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Clinical Presentation and Bacteriology of Eyebrow Infections: The Massachusetts Eye and Ear Infirmary Experience (2008-2015) by Carniciu, Anaïs L, Chou, Jonathan, Leskov, Ilya, Freitag, Suzanne K

“…This study retrospectively reviews preseptal cellulitis and abscesses involving the eyebrow to elucidate the bacteriology and potential causative factors. A…”
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Rapid generation of human B-cell lymphomas via combined expression of Myc and Bcl2 and their use as a preclinical model for biological therapies by Leskov, I, Pallasch, C P, Drake, A, Iliopoulou, B P, Souza, A, Shen, C-H, Schweighofer, C D, Abruzzo, L, Frenzel, L P, Wendtner, C M, Hemann, M T, Chen, J

“…Although numerous mouse models of B-cell malignancy have been developed via the enforced expression of defined oncogenic lesions, the feasibility of generating…”
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