Search Results - "Lesk, Mark R"
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1
Denoising OCT videos based on temporal redundancy
Published in Scientific reports (19-03-2024)“…The identification of eye diseases and their progression often relies on a clear visualization of the anatomy and on different metrics extracted from Optical…”
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2
Non-invasive in vivo measurement of ocular rigidity: Clinical validation, repeatability and method improvement
Published in Experimental eye research (01-01-2020)“…Ocular rigidity (OR) is thought to play a role in the pathogenesis of glaucoma, but the lack of reliable non-invasive measurements has been a major technical…”
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3
Transplantation of Mesenchymal Stem Cells Promotes Tissue Regeneration in a Glaucoma Model Through Laser‐Induced Paracrine Factor Secretion and Progenitor Cell Recruitment
Published in Stem cells (Dayton, Ohio) (01-06-2013)“…Among bone marrow cells, hematopoietic and mesenchymal components can contribute to repair damaged organs. Such cells are usually used in acute diseases but…”
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4
The Association between the Pulsatile Choroidal Volume Change and Ocular Rigidity
Published in Ophthalmology science (Online) (01-11-2024)“…To assess the relationship between the pulsatile choroidal volume change (ΔV) and ocular rigidity (OR), an important biomechanical property of the eye. This is…”
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5
Optic Nerve Head Pulsatile Displacement in Open-Angle Glaucoma after Intraocular Pressure Reduction Measured by Optical Coherence Tomography: A Pilot Study
Published in Bioengineering (Basel) (01-05-2024)“…This study investigated the effect of intraocular pressure (IOP) reduction on pulsatile displacement within the optic nerve head (ONH) in primary open-angle…”
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6
Determinants of Adherence to Glaucoma Medical Therapy in a Long-term Patient Population
Published in Journal of glaucoma (01-03-2009)“…PURPOSEEstimate patient adherence to glaucoma medications and identify potential determinants of nonadherence. DESIGNDescriptive study. METHODSTwo hundred…”
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7
Ocular rigidity and choroidal thickness changes in response to microgravity: A case study
Published in American journal of ophthalmology case reports (01-12-2023)“…PurposeTo evaluate ocular rigidity and choroidal thickness changes in response to microgravity and the Valsalva maneuver in a private astronaut…”
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8
Mapping Pulsatile Optic Nerve Head Deformation Using OCT
Published in Ophthalmology science (Online) (01-12-2022)“…To develop a noninvasive technique to quantitatively assess the pulsatile deformation due to cardiac contractions of the optic nerve head (ONH). Evaluation of…”
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9
Postmenopausal hormone therapy increases retinal blood flow and protects the retinal nerve fiber layer
Published in Investigative ophthalmology & visual science (01-05-2010)“…To investigate whether postmenopausal hormone therapy (HT) increases retinal and ONH blood flow (BF) and protects ONH topography and the function of retinal…”
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10
Measurement of ocular fundus pulsation in healthy subjects using a novel Fourier-domain optical coherence tomography
Published in Investigative ophthalmology & visual science (21-11-2011)“…Anomalies in the pulsatility of the eye have been associated with many types of ocular pathology. Estimation of ocular pulsatility is usually obtained by…”
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11
The heritability of glaucoma-related traits corneal hysteresis, central corneal thickness, intraocular pressure, and choroidal blood flow pulsatility
Published in PloS one (30-01-2013)“…The purpose of this work was to investigate the heritability of potential glaucoma endophenotypes. We estimated for the first time the heritability of the…”
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12
Analysis of pulsatile retinal movements by spectral-domain low-coherence interferometry: influence of age and glaucoma on the pulse wave
Published in PloS one (30-01-2013)“…Recent studies have shown that ocular hemodynamics and eye tissue biomechanical properties play an important role in the pathophysiology of glaucoma…”
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13
Patch graft using collagen matrix (Ologen) for glaucoma drainage device exposure in a patient with Boston Keratoprosthesis type 1
Published in American journal of ophthalmology case reports (01-12-2018)“…To report the first successfully treated case of recurrent tube exposure in a patient with the Boston Keratoprosthesis type 1 with a collagen matrix patch…”
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14
Baseline Factors Predictive of SLT Response: A Prospective Study
Published in Journal of Ophthalmology (01-01-2012)“…Purpose. To study the response to Selective Laser Trabeculoplasty (SLT) according to baseline medical treatment, angle pigmentation, age, diagnosis (open-angle…”
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15
The Association Between Ocular Rigidity and Neuroretinal Damage in Glaucoma
Published in Investigative ophthalmology & visual science (05-11-2020)“…Ocular rigidity (OR) is an important biomechanical property, thought to be relevant in the pathophysiology of open-angle glaucoma (OAG). This study aims to…”
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16
Quantification of Hypotony Maculopathy Using Spectral-Domain Optical Coherence Tomography
Published in Journal of glaucoma (01-04-2023)“…We provide a free-to-use, open-source algorithm to quantify macular hypotony based on optical coherence tomography (OCT) images. This numerical approach…”
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17
Ocular Rigidity and Current Therapy
Published in Current eye research (01-02-2023)“…Purpose: Ocular rigidity (OR) is an important biomechanical parameter of the eye accounting for the material and geometrical properties of the corneoscleral…”
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18
Evaluation of optic nerve head and peripapillary retinal blood flow in glaucoma patients, ocular hypertensives, and normal subjects
Published in American journal of ophthalmology (01-12-2003)“…To compare optic nerve head (ONH) and peripapillary retinal blood flow in subjects with open-angle glaucoma (OAG), ocular hypertension (OHT), and normal eyes…”
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19
Surgical Outcome of Replacing a Failed Ahmed Glaucoma Valve by a Baerveldt Glaucoma Implant in the Same Quadrant in Refractory Glaucoma
Published in Journal of glaucoma (01-05-2018)“…PURPOSE:To describe the surgical technique and outcomes in eyes that underwent surgery to replace a failed Ahmed valve by a Baerveldt glaucoma implant in the…”
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20
Ocular rigidity and neuroretinal damage in patients with vasospasticity: a pilot study
Published in Canadian journal of ophthalmology (01-08-2023)“…Evidence suggests that ocular blood flow dysregulation in patients with vasospasticity could occur in response to biomechanical stimuli, contributing to optic…”
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