Search Results - "Lesh, Randy W."
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Existing and Emerging Biomarkers for Immune Checkpoint Immunotherapy in Solid Tumors
Published in Advances in therapy (01-10-2019)“…In the last few years, immunotherapy has transformed the way we treat solid tumors, including melanoma, lung, head neck, breast, renal, and bladder cancers…”
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Prevalence of pathogenic variants in DNA damage response and repair genes in patients undergoing cancer risk assessment and reporting a personal history of early-onset renal cancer
Published in Scientific reports (11-08-2020)“…Pathogenic variants (PVs) in multiple genes are known to increase the risk of early-onset renal cancer (eoRC). However, many eoRC patients lack PVs in…”
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Triological Best Practice: What is the Appropriate Objective Testing for Patients with Suspected Laryngopharyngeal Reflux?
Published in The Laryngoscope (01-04-2024)Get full text
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Operative technique: Pectoralis major flap with rib
Published in Head & neck (01-03-2024)“…The osteomyocutaneous pectoralis major flap was first described in 1980 and provides a single stage reconstructive option for poor free flap or pectoralis…”
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Therapeutic implications of germline vulnerabilities in DNA repair for precision oncology
Published in Cancer treatment reviews (01-03-2022)“…•Growing appreciation that germline variation in DNA repair predicts response to multiple therapeutic strategies.•Germline testing has identified clinically…”
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Abstract 349: Association of DNA damage response capacity with neoadjuvant chemoradiation response in locally advanced rectal cancer
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Background: Locally advanced rectal cancer (RC) cases are ~60% of newly diagnosed RCs, with neoadjuvant chemoradiation therapy (nCRT) followed by surgery as…”
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Predictors of and outcomes related to perioperative myocardial injury post‐tracheotomy
Published in World journal of otorhinolaryngology - head and neck surgery (24-10-2024)Get full text
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