Search Results - "Leserer, Saskia"
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Time series clustering of T cell subsets dissects heterogeneity in immune reconstitution and clinical outcomes among MUD-HCT patients receiving ATG or PTCy
Published in Frontiers in immunology (20-03-2023)“…Anti-T-lymphocyte globulin (ATG) or post-transplant cyclophosphamide (PTCy) prevent graft-versus-host disease (GVHD) after hematopoietic cell transplantation…”
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Impact of CMV reactivation on relapse of acute myeloid leukemia after HCT is dependent on disease stage and ATG
Published in Blood advances (11-01-2022)“…Cytomegalovirus (CMV) reactivation is a frequent complication after allogeneic hematopoietic cell transplantation (HCT), whose impact on clinical outcome, in…”
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Combined Analysis of Early CD4 + T Cell Counts and CMV Serostatus May Improve CMV Risk Assessment after Allogeneic Hematopoietic Cell Transplantation
Published in Cells (Basel, Switzerland) (26-11-2021)“…The incidence and severity of viral complications after cellular therapy are highly variable. Recent publications describe relevant interactions between the…”
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Immune Reconstitution after Allogeneic Hematopoietic Cell Transplantation: Comparing Post-Transplant Cyclophosphamide Versus Anti-T-Lymphocyte Globulin As Graft-Versus-Host Disease Prophylaxis in a Retrospective Cohort Study
Published in Blood (13-11-2019)“…Introduction: Both post-transplant cyclophosphamide (PT-Cy) and anti-T-lymphocyte globulin (ATLG) eliminate proliferating allo-reactive T cells after…”
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Cytomegalovirus kinetics after hematopoietic cell transplantation reveal peak titers with differential impact on mortality, relapse and immune reconstitution
Published in American journal of hematology (01-04-2021)“…Even in the era of PCR‐based monitoring, prophylaxis, and preemptive therapy, Cytomegalovirus (CMV) viremia remains a relevant cause of non‐relapse mortality…”
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Early Cytomegalovirus Reactivation and Donor Constellation Reduce Early and Late Relapse Incidence of Acute Myeloid Leukemia in a Long-Term Study
Published in Blood (29-11-2018)“…Introduction After allogeneic cell transplantation (HCT) for acute myeloid leukemia (AML) relapse remains the main cause of morbidity and mortality. Relapse…”
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Optimizing anti‐T‐lymphocyte globulin dosing to improve long‐term outcome after unrelated hematopoietic cell transplantation for hematologic malignancies
Published in American journal of transplantation (01-03-2020)“…Prophylaxis of graft‐versus‐host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HCT) remains challenging. Because prospective…”
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