Search Results - "Lescoe, M K"

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer by Fishel, R, Lescoe, M K, Rao, M R, Copeland, N G, Jenkins, N A, Garber, J, Kane, M, Kolodner, R

“…We have identified a human homolog of the bacterial MutS and S. cerevisiae MSH proteins, called hMSH2. Expression of hMSH2 in E. coli causes a dominant mutator…”
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Purified human MSH2 protein binds to DNA containing mismatched nucleotides by FISHEL, R, EWEL, A, LESCOE, M. K

“…The human hMSH2 protein is a member of a highly conserved family of postreplication mismatch repair components found from bacteria to humans. Alterations of…”
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Differential cellular expression of the human MSH2 repair enzyme in small and large intestine by WILSON, T. M, EWEL, A, DUGUID, J. R, EBLE, J. N, LESCOE, M. K, FISHEL, R, KELLEY, M. R

“…The human MSH2 (hMSH2) protein is responsible for the initial recognition of mismatched nucleotides during the postreplication mismatch repair process. Loss of…”
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Binding of Mismatched Microsatellite DNA Sequences by the Human MSH2 Protein by Fishel, Richard, Ewel, Amy, Lee, Suman, Lescoe, Mary Kay, Griffith, Jack

“…Alteration of the human mismatch repair gene hMSH2 has been linked to the microsatellite DNA instability found in hereditary nonpolyposis colon cancer and…”
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Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer by BRONNER, C. E, BAKER, S. M, TANNERGÅRD, P, BOLLAG, R. J, GODWIN, A. R, WARD, D. C, NORDENSKJØLD, M, FISHEL, R, KOLODNER, R, LISKAY, R. M, MORRISON, P. T, WARREN, G, SMITH, L. G, LESCOE, M. K, KANE, M, EARABINO, C, LIPFORD, J, LINDBLOM, A

“…The human DNA mismatch repair gene homologue hMSH2, on chromosome 2p is involved in hereditary non-polyposis colon cancer (HNPCC). On the basis of linkage…”
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The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer by Fishel, R, Lescoe, M K, Rao, M R, Copeland, N G, Jenkins, N A, Garber, J, Kane, M, Kolodner, R

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A High-Throughput HERG Potassium Channel Function Assay: An Old Assay with a New Look by Cheng†, Charles S., Alderman†, Dawn, Kwash, Jennifer, Dessaint, John, Patel, Rita, Lescoe, Mary Kay, Kinrade, Michele Bennett, Yu, Weifeng

“…ABSTRACT In this paper, we describe an assay using radioactive rubidium (86Rb) efflux to screen functional human ether-a go-go-related gene (HERG) K + channels…”
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Binding of mismatched microsatellite DNA sequenes by the human MSH2 protein by FISHEL, R, EWEL, A, LEE, S, LESCOE, M. K, GIFFITH, J

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Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer by Bronner, CE, Baker, S M, Morrison, P T, Warren, G, Smith, L G, Lescoe, M K, Kane, M, Earabino, C, Lipford, J, Lindblom, A, Tannergaard, P, Bollag, R J, Godwin, A R, Ward, D C, Liskayy, R M

“…The human DNA mismatch repair gene homologue, hMSH2, on chromosome 2p is involved in hereditary non-polyposis colon cancer (HNPCC). On the basis of linkage…”
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