Search Results - "Lesan, Vadim"

Liver stiffness as surrogate parameter in emergency assessment for inpatient health care utilization by Kaddu-Mulindwa, Dominic, von Martial, Marius, Thiel-Bodenstaff, Angela, Lesan, Vadim, Ewen, Sebastian, Mahfoud, Felix, Lammert, Frank, Krawczyk, Marcin

“…Transient elastography (TE) allows non-invasive quantification of liver stiffness (LSM) and steatosis (controlled attenuation parameter, CAP). Here we test the…”
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A single center retrospective study on real world CAR T-cell therapy: focus on early hematological toxicity by Lesan, Vadim, Christofyllakis, Konstantinos, Bewarder, Moritz, Thurner, Lorenz, Bittenbring, Jörg

“…Patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL), mantle cell lymphoma (MCL) and multiple myeloma have poor outcomes. CAR-T completely…”
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Impact of vincristine dose reduction on outcomes of patients with aggressive B-cell lymphoma treated with (R) - CHOP by Bewarder, Moritz, Kaddu-Mulindwa, Dominic, Kos, Igor Age, Lesan, Vadim, Held, Gerhard, Poeschel, Viola, Thurner, Lorenz, Bittenbring, Joerg Thomas, Schmitz, Norbert, Truemper, Lorenz, Pfreundschuh, Michael, Christofyllakis, Konstantinos, Loeffler, Markus, Altmann, Bettina, Ziepert, Marita

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Vitamin D Enhances Immune Effector Pathways of NK Cells Thus Providing a Mechanistic Explanation for the Increased Effectiveness of Therapeutic Monoclonal Antibodies by Christofyllakis, Konstantinos, Neumann, Frank, Bewarder, Moritz, Thurner, Lorenz, Kaddu-Mulindwa, Dominic, Kos, Igor Age, Lesan, Vadim, Bittenbring, Joerg Thomas

“…Patients with diffuse large cell lymphoma who have an adequate vitamin D supply derive significantly more benefit from immuno-chemotherapy with rituximab than…”
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Insertion site of central venous catheter correlates with catheter-related infectious events in patients undergoing intensive chemotherapy by Rixecker, Torben, Lesan, Vadim, Ahlgrimm, Manfred, Thurner, Lorenz, Bewarder, Moritz, Murawski, Niels, Christofyllakis, Konstantinos, Altmeyer, Sarah, Bick, Angelika, Stilgenbauer, Stephan, Bittenbring, Joerg Thomas, Kaddu-Mulindwa, Dominic

“…Patients undergoing intensive chemotherapy are usually in need for central venous catheters (CVC). Due to contradictory study results, relation of insertion…”
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Successful treatment of refractory donor‐specific‐human leukocyte antigen‐antibody‐induced primary graft‐failure with daratumumab: A case report by Lesan, Vadim, Melivadze, Ketevani, Hein, Johannes, Ahlgrimm, Manfred, Schunk, Stefan, Bewarder, Moritz, Christofyllakis, Konstantinos, Bittenbring, Joerg Thomas, Thurner, Lorenz

“…Donor‐specific anti‐human leukocyte antigen (HLA) antibodies represent a main cause of primary graft failure specifically in the setting of haploidentical stem…”
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Killer immunoglobulin-like receptor 2DS5 is associated with recovery from coronavirus disease 2019 by Lesan, Vadim, Bewarder, Moritz, Metz, Carlos, Becker, André, Mang, Sebastian, Regitz, Evi, Thurner, Lorenz, Neumann, Frank, Kos, Igor, Christofyllakis, Konstantinos, Danziger, Guy, Stilgenbauer, Stephan, Bals, Robert, Lepper, Philipp M., Kaddu-Mulindwa, Dominic, Rixecker, Torben

“…Background Despite numerous advances in the identification of risk factors for the development of severe coronavirus disease 2019 (COVID-19), factors that…”
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Ars2‐containing bispecific, Fab‐ and IgG1‐format BAR‐bodies to target DLBCL cells by Kiefer, Maximilian, Thurner, Lorenz, Bock, Theresa, Cetin, Onur, Kos, Igor, Lesan, Vadim, Kaddu‐Mulindwa, Dominic, Bittenbring, Joerg Thomas, Fadle, Natalie, Regitz, Evi, Hoth, Markus, Neumann, Frank, Preuss, Klaus‐Dieter, Pfreundschuh, Michael, Christofyllakis, Konstantinos, Bewarder, Moritz

“…Despite recent advances in the therapy of diffuse large B‐cell lymphoma, not otherwise specified (DLBCL), around 30% of patients develop refractory disease or…”
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Indeterminate Dendritic Cell Tumor With Persistent Complete Metabolic Response to BRAF/MEK Inhibition by Thurner, Lorenz, Bewarder, Moritz, Rosar, Florian, Orth, Patrick, Meuter, Raoul Boris, Rixecker, Torben, Lesan, Vadim, Kohn, Dieter Michael, Schneider, Günther, Baumhoer, Daniel, Bohle, Rainer Maria, Veith, Christian, Bittenbring, Joerg Thomas

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Progression-free survival estimates are shaped by specific censoring rules: Implications for PFS as an endpoint in cancer randomized trials by Lesan, Vadim, Olivier, Timothée, Prasad, Vinay

“…Kaplan-Meier analysis hinges on the assumption that patients who are censored– lost to follow-up, or only recently enrolled on the study– are no different, on…”
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Monocyte Subpopulations and Their Expression of HLA-DR and CD300e after Allogeneic Stem Cell Transplantation in Patients with or without GvHD by Age Kos, Igor, Bittenbring, Jörg-Thomas, Cetin, Onur, Lesan, Vadim, Christofyllakis, Konstantinos, Neumann, Frank, Thurner, Lorenz, Bewarder, Moritz

“…Introduction: Graft versus host disease (GvHD) is a complex immune process that can affect up to 50% of patients undergoing allogeneic stem cell…”
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330 LIVER STIFFNESS MEASUREMENTS IN EMERGENCY TRIAGE PREDICT INPATIENT HEALTH CARE UTILIZATION by Kaddu-Mulindwa, Dominic, von Martial, Marius, Lesan, Vadim, Lammert, Frank, Krawczyk, Marcin

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An inherited genetic variant of the CEP72 gene is associated with the development of vincristine-induced peripheral neuropathy in female patients with aggressive B-cell lymphoma by Christofyllakis, Konstantinos, Kaddu-Mulindwa, Dominic, Lesan, Vadim, Rixecker, Torben, Kos, Igor Age, Held, Gerhard, Regitz, Evi, Pfreundschuh, Michael, Bittenbring, Joerg Thomas, Thurner, Lorenz, Poeschel, Viola, Ziepert, Marita, Altmann, Bettina, Bewarder, Moritz

“…Vincristine-induced peripheral neuropathy (VIPN) is an adverse effect of regimens used for the treatment of aggressive B-cell non-Hodgkin lymphoma (B-NHL). A…”
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Autoantibody mediated deficiency of IL-36-receptor antagonist in a subset of patients with psoriasis and psoriatic arthritis by Hoffmann, Marie-Christin, Fadle, Natalie, Regitz, Evi, Kos, Igor Age, Cetin, Onur, Lesan, Vadim, Preuss, Klaus-Dieter, Zaks, Marina, Stöger, Elisabeth, Zimmer, Vincent, Klemm, Philipp, Assmann, Gunter, Pfeifer, Jochen, Bittenbring, Joerg Thomas, Bewarder, Moritz, Vogt, Thomas, Pföhler, Claudia, Thurner, Bernhard, Kessel, Christoph, Thurner, Lorenz

“…•Autoantibodies targeting the IL-36 receptor antagonist (IL-36Ra) occured in subgroups of patients with PsA and Pso.•IL-36Ra-autoantibodies depleted IL-36Ra…”
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A Randomized, Open-Label, Phase 3 Study of Acalabrutinib in Combination with Rituximab and Reduced Dose CHOP (R-miniCHOP) in Older Adults with Untreated Diffuse Large B-Cell Lymphoma (ARCHED / GLA 2022-1) by Christofyllakis, Konstantinos, Poeschel, Viola, Altmann, Bettina, Maurer, Stephanie, Lesan, Vadim, Bittenbring, Jörg, Age Kos, Igor, Kaddu-Mulindwa, Dominic, Abdi, Zanir, Fleser, Octavian, Altmeyer, Sarah, Neuendorff, Nina Rosa, Nickelsen, Maike, Held, Gerhard, Dreyling, Martin, Zettl, Florian, Buske, Christian, Lenz, Georg, Glass, Bertram, Chapuy, Bjoern, Schmitz, Norbert, Vassilakopoulos, Theodoros, Ott, German, Siebert, Reiner, Viardot, Andreas, Scherer, Florian, Schmitz, Roland, Rosenwald, Andreas, Hellwig, Dirk, Loeffler, Markus, Stilgenbauer, Stephan, Thurner, Lorenz, Bewarder, Moritz, Ziepert, Marita

“…Background Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma subtype, and its incidence increases with age. Approximately 40% of patients with…”
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Increased B‐cell activity with consumption of activated monocytes in severe COVID‐19 patients by Kos, Igor, Balensiefer, Benedikt, Lesan, Vadim, Kaddu‐Mulindwa, Dominic, Thurner, Lorenz, Christofyllakis, Konstantin, Bittenbring, Joerg Thomas, Ahlgrimm, Manfred, Seiffert, Martina, Wagenpfeil, Stefan, Bewarder, Yvonne, Neumann, Frank, Rixecker, Torben, Smola, Sigrun, Link, Andreas, Krawczyk, Marcin, Lammert, Frank, Lepper, Philipp M., Bals, Robert, Stilgenbauer, Stephan, Bewarder, Moritz

“…The pathogenesis of autoimmune complications triggered by SARS‐CoV2 has not been completely elucidated. Here, we performed an analysis of the cellular immune…”
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IgG seroprevalence of COVID‐19 among people living with HIV or at high risk of HIV in south‐west Germany: A seroprevalence study by Kaddu‐Mulindwa, Dominic, Keuser, Lukas, Lesan, Vadim, Rissland, Jürgen, Smola, Sigrun, Werdecker, Victoria, Stilgenbauer, Stephan, Christofyllakis, Konstantinos, Thurner, Lorenz, Bewarder, Moritz, Lohr, Benedikt, Lutz, Jens, Lohse, Stefan, Rieke, Ansgar

“…Objectives Seroprevalence studies of SARS‐CoV‐2 have shown that there is a high number of undiagnosed missing cases. Seroprevalence of SARS‐CoV‐2 in people…”
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Spontaneous regression of a plasmablastic lymphoma with MYC rearrangement by Yordanova, Krista, Stilgenbauer, Stephan, Bohle, Rainer M., Lesan, Vadim, Thurner, Lorenz, Kaddu‐Mulindwa, Dominic, Bittenbring, Jörg T., Scharberger, Matthias, Aßmann, Gunter, Bewarder, Moritz

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Significant reduced loss of bone mineral density after four vs. six cycles of R-CHOP: an analysis of the FLYER-trial by Kaddu-Mulindwa, Dominic, Lesan, Vadim, Berdel, Christian, Stilgenbauer, Stephan, Bewarder, Moritz, Thurner, Lorenz, Witzens-Harig, Mathias, Viardot, Andreas, Soekler, Martin, Keller, Ulrich, Truemper, Lorenz, Christofyllakis, Konstantinos, Fleser, Octavian, Bittenbring, Joerg Thomas, Poeschel, Viola, Held, Gerhard, Jagoda, Philippe

“…Patients with diffuse large B-cell lymphoma (DLBCL) treated with the R-CHOP regime receive a high cumulative dose of prednisone. We used computer…”
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KIR2DS1–HLA-C status as a predictive marker for benefit from rituximab: a post-hoc analysis of the RICOVER-60 and CLL8 trials by Kaddu-Mulindwa, Dominic, Altmann, Bettina, Robrecht, Sandra, Ziepert, Marita, Regitz, Evi, Tausch, Eugen, Held, Gerhard, Poeschel, Viola, Lesan, Vadim, Bittenbring, Joerg Thomas, Thurner, Lorenz, Pfreundschuh, Michael, Christofyllakis, Konstantinos, Truemper, Lorenz, Loeffler, Markus, Schmitz, Norbert, Hoth, Markus, Hallek, Michael, Fischer, Kirsten, Stilgenbauer, Stephan, Bewarder, Moritz, Rixecker, Torben Millard

“…The addition of rituximab to chemotherapy has substantially improved outcomes for patients with B-cell malignancies. The mechanisms of action of rituximab…”
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