Search Results - "Lesage, G"
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1
Cost minimization in a full-scale conventional wastewater treatment plant: associated costs of biological energy consumption versus sludge production
Published in Water science and technology (01-11-2017)“…Energy consumption and sludge production minimization represent rising challenges for wastewater treatment plants (WWTPs). The goal of this study is to…”
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2
Petrology and geochemistry of the Saga and Sangsang ophiolitic massifs, Yarlung Zangbo Suture Zone, Southern Tibet: Evidence for an arc–back-arc origin
Published in Lithos (01-11-2009)“…The Saga and Sangsang ophiolites are located about 600 and 450 km west of Lhasa and represent a western extention of the central portion of the Yarlung Zangbo…”
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3
Short-term effect of reclaimed wastewater quality gradient on soil microbiome during irrigation
Published in The Science of the total environment (25-11-2023)“…To investigate the effect of wastewater (WW) treatment on soil bacterial communities, water of different quality was used to irrigate eight lettuces per tank:…”
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4
The relative reinforcing efficacy of nicotine in an adolescent rat model of attention-deficit hyperactivity disorder
Published in Frontiers in psychiatry (15-05-2023)“…Attention-deficit/hyperactivity disorder (ADHD) is an independent risk factor for tobacco use disorder. Individuals with ADHD are more likely to begin smoking…”
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5
Pharmacokinetic correlates of the effects of a heroin vaccine on heroin self-administration in rats
Published in PloS one (23-12-2014)“…The purpose of this study was to evaluate the effects of a morphine-conjugate vaccine (M-KLH) on the acquisition, maintenance, and reinstatement of heroin…”
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6
Flavor-specific enhancement of electronic cigarette liquid consumption and preference in mice
Published in Drug and alcohol dependence (01-06-2020)“…•Fruit flavor, but not tobacco flavor, enhances e-liquid consumption and preference.•The nicotine-free flavored e-liquid is not preferred over nicotine…”
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7
Attenuating nicotine’s effects with high affinity human anti-nicotine monoclonal antibodies
Published in PloS one (30-07-2021)“…Use of nicotine-specific monoclonal antibodies (mAbs) to sequester and reduce nicotine distribution to brain has been proposed as a therapeutic approach to…”
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8
Magnitude and predictors of elasticity of demand for morphine are similar in male and female rats
Published in Frontiers in behavioral neuroscience (29-08-2024)“…Sex differences in vulnerability to opioid use disorder (OUD) have been reported in some clinical and preclinical studies, but findings are mixed and further…”
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Cigarette Smoke Extract, but Not Electronic Cigarette Aerosol Extract, Inhibits Monoamine Oxidase in vitro and Produces Greater Acute Aversive/Anhedonic Effects Than Nicotine Alone on Intracranial Self-Stimulation in Rats
Published in Frontiers in neuroscience (25-05-2022)“…Conventional tobacco cigarettes appear to have greater abuse liability than non-combusted products such as electronic cigarettes (ECs) and nicotine replacement…”
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10
Effects of an oxycodone conjugate vaccine on oxycodone self-administration and oxycodone-induced brain gene expression in rats
Published in PloS one (15-07-2014)“…Prescription opioid abuse is an increasing public health concern in the USA. A vaccine comprising a hapten (OXY) conjugated to the carrier protein keyhole…”
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11
Effects of nicotine and minor tobacco alkaloids on intracranial-self-stimulation in rats
Published in Drug and alcohol dependence (01-08-2015)“…Highlights • We tested effects of tobacco alkaloids on intracranial self-stimulation (ICSS). • Moderate nicotine doses reduced while high nicotine doses…”
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12
Nicotine self-administration in the rat: effects of hypocretin antagonists and changes in hypocretin mRNA
Published in Psychopharmacologia (01-04-2010)“…Rationale The hypocretin (hcrt) system has been implicated in addiction-relevant effects of several drugs, but its role in nicotine dependence has been little…”
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13
Brewery wastewater treatment using MBR coupled with nanofiltration or electrodialysis: biomass acclimation and treatment efficiency
Published in Water science and technology (01-06-2018)“…Breweries release significant amounts of wastewater loaded with various organic and mineral materials. Prior studies of membrane bioreactor (MBR) wastewater…”
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14
The anti-(+)-methamphetamine monoclonal antibody mAb7F9 attenuates acute (+)-methamphetamine effects on intracranial self-stimulation in rats
Published in PloS one (05-03-2015)“…Passive immunization with monoclonal antibodies (mAbs) against (+)-methamphetamine (METH) is being evaluated for the treatment of METH addiction. A human/mouse…”
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15
The nicotine-degrading enzyme NicA2 reduces nicotine levels in blood, nicotine distribution to brain, and nicotine discrimination and reinforcement in rats
Published in BMC biotechnology (24-07-2018)“…The bacterial nicotine-degrading enzyme NicA2 isolated from P. putida was studied to assess its potential use in the treatment of tobacco dependence. Rats were…”
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16
Pharmacological mechanisms underlying the efficacy of antibodies generated by a vaccine to treat oxycodone use disorder
Published in Neuropharmacology (01-09-2021)“…Therapeutic vaccines offer a viable strategy to treat opioid use disorders (OUD) complementary to current pharmacotherapies. The candidate Oxy(Gly)4-sKLH…”
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17
Fate and Toxicity of Carbamazepine and Its Degradation By-Products During Coupling of Ozonation and Nanofiltration for Urban Wastewater Reuse
Published in Frontiers in environmental chemistry (09-12-2021)“…Occurrence of emerging organic micropollutants in water bodies and their effects are a concern related to quality of reused water. Advanced oxidation processes…”
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18
A TLR7/8 agonist increases efficacy of anti-fentanyl vaccines in rodent and porcine models
Published in npj vaccines (24-07-2023)“…Opioid use disorders (OUD) and overdose are public health threats worldwide. Widespread access to highly potent illicit synthetic opioids such as fentanyl is…”
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19
Dynamic modeling of biodegradation and volatilization of hazardous aromatic substances in aerobic bioreactor
Published in Water research (Oxford) (15-10-2012)“…The aerobic biological process is one of the best technologies available for removing hazardous organic substances from industrial wastewaters. But in the case…”
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20
Locomotor activity does not predict individual differences in morphine self-administration in rats
Published in Pharmacology, biochemistry and behavior (01-03-2018)“…Understanding factors contributing to individual differences in opioid addiction vulnerability is essential for developing more effective preventions and…”
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