Search Results - "Lertratanangkoon, K"

O- and S-methylated bromothiocatechols by Lertratanangkoon, K

“…Bromobenzene is metabolized by the Hartley guinea pig to two different bromothiocatechols, 4-bromo-2-hydroxythiophenol and 5-bromo-2-hydroxythiophenol. Both…”
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Glutathione Depletion-Induced Thymidylate Insufficiency for DNA Repair Synthesis by Lertratanangkoon, Khingkan, Savaraj, Niramol, Scimeca, Joseph M., Thomas, Mary L.

“…Dietary methionine (Met) deficiency is known to divert folate away from de novo biosyntheses of purines and the pyrimidine, thymidylate, to the resynthesis of…”
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Metabolism of carbamazepine by Lertratanangkoon, K, Horning, M G

“…Thirty-two metabolites of carbamazepine, in addition to the 10,11-epoxide, have been isolated from enzymatically hydrolyzed urine by HPLC and identified by…”
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Bromobenzene metabolism in the rat and guinea pig by Lertratanangkoon, K, Horning, M G

“…The metabolism of bromobenzene was studied in the rat and guinea pig with respect to three considerations: the dose and species dependence of 3-bromophenol…”
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Conversion of bromobenzene to 3-bromophenol. A route to 3- and 4-bromophenol through sulfur-series intermediates derived from the 3,4-oxide by Lertratanangkoon, K, Horning, E C, Horning, M G

“…Premercapturic acids derived from bromobenzene 3,4-oxide were found to act as precursors of 3- and 4-bromophenol in the rat and guinea pig. The 4-S- and 3-S-…”
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Use of saliva in therapeutic drug monitoring by Horning, M G, Brown, L, Nowlin, J, Lertratanangkoon, K, Kellaway, P, Zion, T E

“…We measured the concentrations of phenobarbital, phenytoin, primidone, ethosuximide, antipyrine, and caffeine in paired samples of saliva and plasma by gas…”
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Urinary bivalent sulfur metabolites of phenanthrene excreted by the rat and guinea pig by Lertratanangkoon, K, Horning, M G, Middleditch, B S, Tsang, W S, Griffin, G W

“…After the administration of phenanthrene (50 mg/kg, ip) to young adult male rats and guinea pigs, a series of bivalent sulfur urinary metabolites were isolated…”
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Metabolism of bromobenzene. Analytical chemical and structural problems associated with studies of the metabolism of a model aromatic compound by Horning, E C, Lertratanangkoon, K, Horning, M G

“…Our studies of bromobenzene metabolism have shown that the 3,4-oxide is metabolized to 3- and 4-bromophenol through an extended glutathione pathway. The…”
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Analytical methods for the study of urinary thioether metabolites in the rat and guinea pig by Horning, M G, Sheng, L S, Nowlin, J G, Lertratanangkoon, K, Horning, E C

“…Methods are described for the isolation and identification of three classes of bivalent sulfur metabolites characterized as neutral methylthio ethers, ethyl…”
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High-performance liquid chromatographic separation of carbamazepine metabolites excreted in rat urine by Horning, M G, Lertratanangkoon, K

“…A procedure for the separation and isolation of the urinary metabolites of carbamazepine by reversed-phase high-performance liquid chromatography is described…”
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Isolation of drugs and drug metabolites from biological fluids by use of salt-solvent pairs by Horning, M G, Gregory, P, Nowlin, J, Stafford, M, Lertratanangkoon, K, Butler, C, Stillwell, W G, Hill, R M

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Alterations of DNA methylation by glutathione depletion by Lertratanangkoon, Khingkan, Wu, Chun J, Savaraj, Niramol, Thomas, Mary L

“…One of the most consistent findings in cancer cells is an overall decrease of 5-methylcytosine content in DNA. The causes that lead to this alteration are not…”
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Pathways of formation of 2-, 3- and 4-bromophenol from bromobenzene. Proposed mechanism for C-S lyase reactions of cysteine conjugates by Lertratanangkoon, K, Horning, E C, Horning, M G

“…Bromobenzene is metabolized by the rat and guinea pig to 2-, 3- and 4-bromophenol. 3-Bromophenol is formed through the sulfur-series pathway to phenols. This…”
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Use of stable isotopes in measuring low concentrations of drugs and drug metabolites by GC-MS-COM procedures by Horning, M G, Nowlin, J, Lertratanangkoon, K, Stillwell, R N, Stillwell, W G, Hill, R M

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The use of gas chromatographic-mass spectrometric-computer systems in pharmacokinetic studies by Horning, M G, Nowlin, J, Stafford, M, Lertratanangkoon, K, Sommer, K R, Hill, R M, Stillwell, R N

“…Pharmacokinetic studies involving plasma, urine, breast milk, saliva and liver homogenates have been carried out by selective ion detection with a gas…”
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The use of stable isotopes in gas chromatography-mass spectrometric studies of drug metabolism by Horning, M G, Stillwell, W G, Nowlin, J, Lertratanangkoon, K, Carroll, D, Dzidic, I, Stillwell, R N, Horning, E C, Hill, R M

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Anticonvulsant drug monitoring by GC-MS-COM techniques by Horning, M G, Lertratanangkoon, K, Nowlin, J, Stillwell, W G, Stillwell, R N, Zion, T E, Kellaway, P, Hill, R M

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Methyl-donor deficiency due to chemically induced glutathione depletion by KHINGKAN LERTRATANANGKOON, ORKISZEWSKI, R. S, SCIMECA, J. M

“…Dietary deficiency of methionine (Met) is known to deplete cellular Met and cause DNA hypomethylation, but depletion of Met and impairment in methylation due…”
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Inhibition of glutathione synthesis with propargylglycine enhances N-acetylmethionine protection and methylation in bromobenzene-treated Syrian hamsters by Lertratanangkoon, K, Scimeca, J M, Wei, J N

“…The finding that liver necrosis caused by the environmental glutathione (GSH)-depleting chemical, bromobenzene (BB) is associated with marked impairment in O-…”
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Formation of phenol and thiocatechol metabolites from bromobenzene premercapturic acids through pyridoxal phosphate-dependent C-S lyase activity by Lertratanangkoon, K, Denney, D

“…When N-acetyl-S-(2-hydroxy-4-bromocyclohexa-3,5-dienyl)-L-cystein e (4-S-premercapturic acid) and N-acetyl-S-(2-hydroxy-5-bromocyclohexa-3,5-dienyl)-L-cystein…”
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