Search Results - "Leroyer, Aurélie"

Mast cells drive pathologic vascular lesions in Takayasu arteritis by Le Joncour, Alexandre, Desbois, Anne-Claire, Leroyer, Aurélie S., Tellier, Edwige, Régnier, Paul, Maciejewski-Duval, Anna, Comarmond, Cloé, Barete, Stéphane, Arock, Michel, Bruneval, Patrick, Launay, Jean-Marie, Fouret, Pierre, Blank, Ulrich, Rosenzwajg, Michelle, Klatzmann, David, Jarraya, Mohamed, Chiche, Laurent, Koskas, Fabien, Cacoub, Patrice, Kaplanski, Gilles, Saadoun, David

“…Takayasu arteritis (TAK) is a large vessel vasculitis resulting in artery wall remodeling with segmental stenosis and/or aneurysm formation. Mast cells (MCs)…”
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Soluble CD146 as a Potential Target for Preventing Triple Negative Breast Cancer MDA-MB-231 Cell Growth and Dissemination by Sharma, Akshita, Joshkon, Ahmad, Ladjimi, Aymen, Traboulsi, Waël, Bachelier, Richard, Robert, Stéphane, Foucault-Bertaud, Alexandrine, Leroyer, Aurélie S, Bardin, Nathalie, Somasundaram, Indumathi, Blot-Chabaud, Marcel

“…Triple Negative Breast Cancers (TNBC) are the most aggressive breast cancers and lead to poor prognoses. This is due to a high resistance to therapies, mainly…”
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Endothelial-derived microparticles: Biological conveyors at the crossroad of inflammation, thrombosis and angiogenesis by Leroyer, Aurélie S, Anfosso, Francine, Lacroix, Romaric, Sabatier, Florence, Simoncini, Stéphanie, Njock, Sébastien M, Jourde, Noémie, Brunet, Philippe, Camoin-Jau, Laurence, Sampol, José, Dignat-George, Françoise

“…Endothelial microparticles (EMP) are complex vesicular structures that can be shed by activated or apoptotic endothelial cells. EMP are composed of a…”
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Involvement of Multiple Variants of Soluble CD146 in Systemic Sclerosis: Identification of a Novel Profibrotic Factor by Nollet, Marie, Bachelier, Richard, Joshkon, Ahmad, Traboulsi, Waël, Mahieux, Amandine, Moyon, Anais, Muller, Alexandre, Somasundaram, Indumathi, Simoncini, Stéphanie, Peiretti, Franck, Leroyer, Aurélie S., Guillet, Benjamin, Granel, Brigitte, Dignat‐George, Françoise, Bardin, Nathalie, Foucault‐Bertaud, Alexandrine, Blot‐Chabaud, Marcel

“…Objective Systemic sclerosis (SSc) is an autoimmune disorder characterized by excessive fibrosis, immune dysfunction, and vascular damage, in which the…”
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Endothelial-Specific Deletion of CD146 Protects Against Experimental Glomerulonephritis in Mice by Abed, Ahmed, Leroyer, Aurélie S., Kavvadas, Panagiotis, Authier, Florence, Bachelier, Richard, Foucault-Bertaud, Alexandrine, Bardin, Nathalie, Cohen, Clemens D., Lindenmeyer, Maja T., Genest, Magali, Joshkon, Ahmad, Jourde-Chiche, Noémie, Burtey, Stéphane, Blot-Chabaud, Marcel, Dignat-George, Françoise, Chadjichristos, Christos E.

“…CD146 is an endothelial junctional adhesion molecule, which expression is increased in human glomerular diseases. However, the pathological significance of…”
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Vascular endothelial-cadherin is involved in endothelial cell detachment during thrombotic thrombocytopenic purpura by Cauchois, Raphael, Lagarde, Marie, Muller, Romain, Faccini, Julien, Leroyer, Aurélie, Arnaud, Laurent, Poullin, Pascale, Dignat-George, Françoise, Kaplanski, Gilles, Tellier, Edwige

“…Immune thrombotic thrombocytopenic purpura (i-TTP) is a life-threatening thrombotic microangiopathy linked to ADAMTS-13 deficiency. It has long been assumed…”
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Circulating microvesicles correlate with radiation proctitis complication after radiotherapy by Ribault, Alexandre, Benadjaoud, Mohamed Amine, Squiban, Claire, Arnaud, Laurent, Judicone, Coralie, Leroyer, Aurélie S., Rousseau, Alexandra, Huet, Christelle, Guha, Chandan, Benderitter, Marc, Lacroix, Romaric, Flamant, Stephane, Chen, Emily I., Simon, Jean-Marc, Tamarat, Radia

“…In a large retrospective study, we assessed the putative use of circulating microvesicles (MVs), as innovative biomarkers of radiation toxicity in a cohort of…”
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CD40 Ligand+ Microparticles From Human Atherosclerotic Plaques Stimulate Endothelial Proliferation and Angiogenesis by Leroyer, Aurélie S., PhD, Rautou, Pierre-Emmanuel, MD, Silvestre, Jean-Sébastien, PhD, Castier, Yves, MD, PhD, Lesèche, Guy, MD, PhD, Devue, Cécile, BSc, Duriez, Micheline, BSc, Brandes, Ralf P., MD, PhD, Lutgens, Esther, MD, PhD, Tedgui, Alain, PhD, Boulanger, Chantal M., PhD

“…Objectives Our goal was to demonstrate that microparticles (MPs) are the endogenous signal leading to neovessel formation through CD40 ligation in human…”
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Randomized controlled trial protocol to investigate the antiplatelet therapy effect on extracellular vesicles (AFFECT EV) in acute myocardial infarction by Gasecka, Aleksandra, Nieuwland, Rienk, Budnik, Monika, Dignat-George, Françoise, Eyileten, Ceren, Harrison, Paul, Huczek, Zenon, Kapłon-Cieślicka, Agnieszka, Lacroix, Romaric, Opolski, Grzegorz, Pluta, Kinga, van der Pol, Edwin, Postuła, Marek, Leroyer, Aurélie, Siljander, Pia, Sturk, Auguste, Filipiak, Krzysztof J.

“…Activated platelets contribute to thrombosis and inflammation by the release of extracellular vesicles (EVs) exposing P-selectin, phosphatidylserine (PS) and…”
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Soluble CD146, an innovative and non-invasive biomarker of embryo selection for in vitro fertilization by Bouvier, Sylvie, Paulmyer-Lacroix, Odile, Molinari, Nicolas, Bertaud, Alexandrine, Paci, Marine, Leroyer, Aurélie, Robert, Stéphane, Dignat George, Françoise, Blot-Chabaud, Marcel, Bardin, Nathalie

“…Although progress was made in in vitro fertilization (IVF) techniques, the majority of embryos transferred fail to implant. Morphology embryo scoring is the…”
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Immunomodulatory role of Interleukin-33 in large vessel vasculitis by Desbois, Anne-Claire, Cacoub, Patrice, Leroyer, Aurélie S., Tellier, Edwige, Garrido, Marlène, Maciejewski-Duval, Anna, Comarmond, Cloé, Barete, Stéphane, Arock, Michel, Bruneval, Patrick, Launay, Jean-Marie, Fouret, Pierre, Blank, Ulrich, Rosenzwajg, Michelle, Klatzmann, David, Jarraya, Mohamed, Cluzel, Philippe, Koskas, Fabien, Kaplanski, Gilles, Saadoun, David

“…The mechanisms regulating inflammation in large vessels vasculitis (LVV) are poorly understood. Interleukin 33 (IL-33) has been shown to license innate and…”
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Macrophage IL-1β-positive microvesicles exhibit thrombo-inflammatory properties and are detectable in patients with active juvenile idiopathic arthritis by Cambon, Audrey, Rebelle, Charlotte, Bachelier, Richard, Arnaud, Laurent, Robert, Stéphane, Lagarde, Marie, Muller, Romain, Tellier, Edwige, Kara, Yéter, Leroyer, Aurélie, Farnarier, Catherine, Vallier, Loris, Chareyre, Corinne, Retornaz, Karine, Jurquet, Anne-Laure, Tran, Tu-Anh, Lacroix, Romaric, Dignat-George, Françoise, Kaplanski, Gilles

“…IL-1β is a leaderless cytokine with poorly known secretory mechanisms that is barely detectable in serum of patients, including those with an IL-1β-mediated…”
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CD146/sCD146 in the Pathogenesis and Monitoring of Angiogenic and Inflammatory Diseases by Heim, Xavier, Joshkon, Ahmad, Bermudez, Julien, Bachelier, Richard, Dubrou, Cléa, Boucraut, José, Foucault-Bertaud, Alexandrine, Leroyer, Aurélie S, Dignat-George, Francoise, Blot-Chabaud, Marcel, Bardin, Nathalie

“…CD146 is a cell adhesion molecule expressed on endothelial cells, as well as on other cells such as mesenchymal stem cells and Th17 lymphocytes. This protein…”
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Sera From Patients With Minimal Change Disease Increase Endothelial Permeability to Sodium by Daviet, Florence, Blin, Muriel G., Fallague, Karim, Bachelier, Richard, Laforêt, Manon, Carré, Manon, Poitevin, Stéphane, Dignat-George, Françoise, Blot-Chabaud, Marcel, Bardin, Nathalie, Burtey, Stéphane, Jourde-Chiche, Noémie, Leroyer, Aurélie S.

“…E dema is the main symptom of nephrotic syndrome associated to minimal change disease (MCD). Besides the increase in glomerular permeability, possibly induced…”
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Multifaceted role of extracellular vesicles in atherosclerosis by Konkoth, Akhil, Saraswat, Ronald, Dubrou, Cléa, Sabatier, Florence, Leroyer, Aurélie S., Lacroix, Romaric, Duchez, Anne-Claire, Dignat-George, Francoise

“…Extracellular vesicles (EVs) are small vesicles released by the majority of cells in response to cell activation or death stimuli. They are grouped as small…”
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Signaling Pathways and Potential Therapeutic Strategies in Cardiac Fibrosis by Bertaud, Alexandrine, Joshkon, Ahmad, Heim, Xavier, Bachelier, Richard, Bardin, Nathalie, Leroyer, Aurélie S, Blot-Chabaud, Marcel

“…Cardiac fibrosis constitutes irreversible necrosis of the heart muscle as a consequence of different acute (myocardial infarction) or chronic (diabetes,…”
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Microparticles From Human Atherosclerotic Plaques Promote Endothelial ICAM-1–Dependent Monocyte Adhesion and Transendothelial Migration by Rautou, Pierre-Emmanuel, Leroyer, Aurélie S, Ramkhelawon, Bhama, Devue, Cécile, Duflaut, Dominique, Vion, Anne-Clémence, Nalbone, Gilles, Castier, Yves, Leseche, Guy, Lehoux, Stéphanie, Tedgui, Alain, Boulanger, Chantal M

“…RATIONALE AND OBJECTIVE:Membrane-shed submicron microparticles (MPs) released following cell activation or apoptosis accumulate in atherosclerotic plaques,…”
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CD146 (Cluster of Differentiation 146): An Adhesion Molecule Involved in Vessel Homeostasis by Leroyer, Aurélie S, Blin, Muriel G, Bachelier, Richard, Bardin, Nathalie, Blot-Chabaud, Marcel, Dignat-George, Françoise

“…CD146 (cluster of differentiation 146) is an adhesion molecule that is expressed by different cells constituting vessels, particularly endothelial cells. The…”
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Cellular Origins and Thrombogenic Activity of Microparticles Isolated From Human Atherosclerotic Plaques by Leroyer, Aurélie S., BSc, Isobe, Hirotaka, PhD, Lesèche, Guy, MD, PhD, Castier, Yves, MD, PhD, Wassef, Michel, PhD, Mallat, Ziad, MD, PhD, Binder, Bernd R., MD, PhD, Tedgui, Alain, PhD, Boulanger, Chantal M., PhD

“…Cellular Origins and Thrombogenic Activity of Microparticles Isolated From Human Atherosclerotic Plaques Aurélie S. Leroyer, Hirotaka Isobe, Guy Leséche, Yves…”
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CD146 mediates VEGF-induced permeability and promotes melanoma metastasis in vivo by Jouve, Nathalie, Bachelier, Richard, Matinzadeh, Maryam Khalili, Despoix, Nicolas, Vely, Frédéric, Dignat-George, Françoise, Leroyer, Aurélie S

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